Results 31 to 40 of about 710,495 (352)

Phospholipid-anchored and transmembrane versions of either decay-accelerating factor or membrane cofactor protein show equal efficiency in protection from complement-mediated cell damage. [PDF]

Journal of Experimental Medicine, 1991
Decay-accelerating factor (DAF) is a glycosyl-phosphatidylinositol (GPI)-anchored membrane protein that protects cells from complement- mediated damage by regulation of the C3 convertase.
Douglas M. Lublin, K E Coyne
openalex   +2 more sources

Atypical Hemolytic Uremic Syndrome Triggered by Acute Pancreatitis in a Patient with a Membrane Cofactor Protein (CD46) Genetic Variant. [PDF]

Intern Med
Mochizuki K, Toda N, Fujita M, Kurahashi S, Hirashima H, Yoshioka K, Kitagawa T, Ishii A, Komiya T.   +8 more
europepmc   +2 more sources

Export of functional Streptomyces coelicolor alditol oxidase to the periplasm or cell surface of Escherichia coli and its application in whole-cell biocatalysis [PDF]

, 2009
Streptomyces coelicolor A3(2) alditol oxidase (AldO) is a soluble monomeric flavoprotein in which the flavin cofactor is covalently linked to the polypeptide chain.
AJ Driessen, BJ Feilmeier, C Filip, CA Kumamoto, CF Schierle, CM Cho, CR Raetz, D Huber, D Schmid, D Tullman-Ercek, DP Heuts, E Brickman, E Frirdich, E Vrontou, EW van Hellemond, F Forneris, FJ Mergulhao, HC Jung, J Jose, J Luirink, J Zhou, JD Thomas, JS Lee, K Nakai, L Li, M Marrichi, M Shimazu, M Shimazu, MA Turner, MJ Casadaban, MJ Casadaban, ML Wu, MW Fraaije, NG Leferink, P Samuelson, PA Lee, PH Wu, R Federico, S Cristobal, SK Yim, SM Kang, SP Graether, SY Lee, T Baba, T Bruser   +44 more
core   +15 more sources

Microbial Protein Binding to gC1qR Drives PLA2G1B-Induced CD4 T-Cell Anergy

Frontiers in Immunology, 2022
The origin of the impaired CD4 T-cell response and immunodeficiency of HIV-infected patients is still only partially understood. We recently demonstrated that PLA2G1B phospholipase synergizes with the HIV gp41 envelope protein in HIV viremic plasma to ...
Julien Pothlichet, Annalisa Meola, Florence Bugault, Louise Jeammet, Anne G. Savitt, Berhane Ghebrehiwet, Lhousseine Touqui, Lhousseine Touqui, Philippe Pouletty, Frédéric Fiore, Alain Sauvanet, Jacques Thèze   +11 more
doaj   +1 more source

Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria [PDF]

Molecular Microbiology, 1997
Helena Källström, M. Kathryn Liszewski, John P. Atkinson, Ann‐Beth Jonsson   +3 more
openalex   +2 more sources

Cells determine cell density using a small protein bound to a unique tissue-specific phospholipid [PDF]

PeerJ, 2013
Cell density is the critical parameter controlling tendon morphogenesis. Knowing its neighbors allows a cell to regulate correctly its proliferation and collagen production.
Christopher J. Petzold, Richard I. Schwarz   +1 more
doaj   +2 more sources

A membrane‐bound [NiFe]‐hydrogenase large subunit precursor whose C‐terminal extension is not essential for cofactor incorporation but guarantees optimal maturation

MicrobiologyOpen, 2020
[NiFe]‐hydrogenases catalyze the reversible conversion of molecular hydrogen into protons end electrons. This reaction takes place at a NiFe(CN)2(CO) cofactor located in the large subunit of the bipartite hydrogenase module. The corresponding apo‐protein
Sven Hartmann, Stefan Frielingsdorf, Giorgio Caserta, Oliver Lenz   +3 more
doaj   +1 more source

Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity [PDF]

, 2009
Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates.
AG Barbour, AG Barbour, AG Barbour, AG Barbour, AS Coleman, C Neeleman, C Siegel, C Skerka, CA Brissette, Christiane Brenner, CS Brooks, D Raoult, David M. Ojcius, DJ Grab, E Rossmann, E Rossmann, GD Wieland, H Fuchs, J Bunikis, JA Gebbia, JC Scott, JC Setubal, JL Coleman, JV McDowell, K Hartmann, KM Hovis, KM Hovis, KO Sundnes, L Houhamdi, Markus M. Simon, MD Kramer, Melanie Schott, MK Pangburn, NM Ras, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Kraiczy, P Stewart, Peter F. Zipfel, Peter Kraiczy, PF Zipfel, PF Zipfel, PM Southern, RD Horstmann, Reinhard Wallich, S Hammerschmidt, S Kuhn, S Kuhn, S Poltermann, S Ram, Sally J. Cutler, SH Rooijakkers, SJ Cutler, Sonja Grosskinsky, T Meri, T Meri, WR Zuckert   +59 more
core   +13 more sources

Computational Analysis of CD46 Protein Interaction with SARS-CoV-2 Structural Proteins: Elucidating a Putative Viral Entry Mechanism into Human Cells

Viruses, 2023
This study examines an unexplored aspect of SARS-CoV-2 entry into host cells, which is widely understood to occur via the viral spike (S) protein’s interaction with human ACE2-associated proteins.
Pavel Vassiliev, Evgenii Gusev, Maria Komelkova, Andrey Kochetkov, Maria Dobrynina, Alexey Sarapultsev   +5 more
doaj   +1 more source

The Bacterial Photosynthetic Reaction Center as a Model for Membrane Proteins [PDF]

, 1989
Membrane proteins participate in many fundamental cellular processes. Until recently, an understanding of the function and properties of membrane proteins was hampered by an absence of structural information at the atomic level.
Allen, J. P., Feher, G., Komiya, H., Rees, D. C., Yeates, T. O.   +4 more
core   +1 more source