Results 61 to 70 of about 5,777 (152)

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

Meningeal Lymphatic and Glymphatic Structures in a Pelagic Delphinid (Delphinus delphis)

Animals
The glymphatic system, an analog of the peripheral lymphatic system in the brain, and the meningeal lymphatic system are critical to central nervous system health.
Olivia N. Jackson, Tiffany F. Keenan, Nathan P. Nelson-Maney, Sentiel A. Rommel, William A. McLellan, D. Ann Pabst, Alexander M. Costidis, Kathleen M. Caron, Dawn N. Kernagis, David S. Rotstein, Victoria G. Thayer, Craig A. Harms, Marina A. Piscitelli-Doshkov, Paul Doshkov, Lorian E. Schweikert, Kara E. Yopak, Molly Braun, Michael S. Tift   +17 more
doaj   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Case report: meningeal lymphangiogenesis around ependymoma forming along the dura matter

Frontiers in Oncology
Recently, there has been growing interest in the presence and function of meningeal lymphatic vessels, with no direct evidence linking these vessels to primary brain tumors.
Utaro Hino, Ryota Tamura, Masahiro Yo, Yoshitaka Kase, Yoshitaka Kase, Noboru Tsuda, Tsubasa Miyauchi, Junki Sogano, Kosuke Karatsu, Tomoru Miwa, Masahiro Toda   +10 more
doaj   +1 more source

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain

eLife, 2022
The discovery of meningeal lymphatic vessels that drain the CNS has prompted new insights into how immune responses develop in the brain. In this study, we examined how T cell responses against CNS-derived antigen develop in the context of infection.
Michael A Kovacs, Maureen N Cowan, Isaac W Babcock, Lydia A Sibley, Katherine Still, Samantha J Batista, Sydney A Labuzan, Ish Sethi, Tajie H Harris   +8 more
doaj   +1 more source

Fascia, Eh. What Is It? What Is It Good for?

Clinical Anatomy, EarlyView.
ABSTRACT Opinions on the meaning of the term fascia appear to have been diverging for the past quarter century. In 1998, the definition of fascia in the international standard anatomical nomenclature was narrowed by removing the term fascia superficialis.
Paul E. Neumann, Heba Labib, Martin Lhuaire, Noel T. Boaz, Geoffroy P. J. C. Noel, Carlos Suárez‐Quian, Chernet Tessema, Peter J. Ward, Anthony J. Weinhaus, Mahindra K. Anand, Alan J. Detton   +10 more
wiley   +1 more source

Fluid dynamics in aging-related dementias

Neurobiology of Disease, 2023
Recent human and animal model experimental studies revealed novel pathways for fluid movement, immune cell trafficking and metabolic waste clearance in CNS.
Thierno M. Bah, Dominic A. Siler, Aseel H. Ibrahim, Justin S. Cetas, Nabil J. Alkayed   +4 more
doaj   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

Constipation Is Linked to Neuroinflammation in Early Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Constipation is a risk factor for the onset and accelerated progression of Parkinson's disease (PD), but the mechanisms underlying this association are unknown. Neuroinflammation in PD has been demonstrated in postmortem and neuroimaging studies; however, its relationship with constipation has not been investigated.
Marta Camacho, Julia C. Greenland, Alexander R.D. Peattie, Lennart R.B. Spindler, Jonathan Holbrook, Lakmini Kahanawita, Tim D. Fryer, Young T. Hong, Caroline H. Williams‐Gray   +8 more
wiley   +1 more source