Results 61 to 70 of about 6,015 (163)

Technology of the photobiostimulation of the brain’s drainage system during sleep for improvement of learning and memory in male mice [PDF]

, 2023
In this study on healthy male mice using confocal imaging of dye spreading in the brain and its further accumulation in the peripheral lymphatics, we demonstrate stronger effects of photobiomodulation (PBM) on the brain’s drainage system in sleeping vs ...
Adushkina, V, Ageev, V, Blokhina, I, Dmitrenko, A, Dubrovsky, A, Evsukova, A, Fedosov, I, Ilyukov, E, Krupnova, V, Kurths, J, Manzhaeva, M, Myagkov, D, Semyachkina-Glushkovskaya, O, Shirokov, A, Telnova, V, Terskov, A, Tsoy, M, Tuktarov, D, Zaikin, A, Zlatogorskaya, D   +19 more
core  

Aquaporin 4 modulation drives amyloid burden and cognitive abilities in an APPPS1 mouse model of Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Deficiency in the aquaporin‐4 (AQP4) water channel has been linked to impaired amyloid beta (Aβ) clearance. However, a detailed morphopathological analysis of amyloid deposition following AQP4 therapeutic modulation remains unexplored.
Marina Daniela Manescu, Bogdan Catalin, Ioana Baldea, Valentin Octavian Mateescu, Gabriela Camelia Rosu, Ianis Kevyn Stefan Boboc, Anca‐Maria Istrate‐Ofiteru, Ilona Mihaela Liliac, Costin Teodor Streba, Samir Kumar‐Singh, Daniel Pirici   +10 more
wiley   +1 more source

Necropsy Technique and Histological Characterisation of Organs From Neonatal Puppies: What Do We Know?

Veterinary Medicine and Science, Volume 11, Issue 3, May 2025.
The mortality rate of dogs during pregnancy is high. A postmortem examination allows the identification of possible causes of puppy mortality. Newborns present anatomical, physiological and histological characteristics. ABSTRACT Neonatal mortality in dogs is high, ranging from approximately 5% to 35%, yet investigations into its causes and risk factors
Victória Ghedin, Jéssica Cardia de Melo, Fernanda Barthelson Carvalho de Moura, Keylla Helena Nobre Pacífico Pereira, Carlos Mario Gonzalez Zambrano, Juliana Jurado Jiménez, Gabriela Abreu Botelho, Luíz Guilherme Decore Benevenuto, Reiner Silveira de Moraes, Fernando Carmona Dinau, Pedro Pol Ximenes, Ana Júlia Motta da Costa, Natália Freitas de Souza, Maria Clara Boni Raffi, Tatiana Pessoa Onuma, Natália Camargo Faraldo, Maria Lucia Gomes Lourenço, Sérgio Luis Felisbino, Tatiane Terumi Negrão Watanabe, Monica Barthelson Carvalho de Moura, Luis Mauricio Montoya‐Flórez, Francisco Pedraza‐Ordoñez, Noeme Sousa Rocha   +22 more
wiley   +1 more source

Single‐Cell Transcriptomes of Immune Cells from Multiple Compartments Redefine the Ontology of Myeloid Subtypes Post‐Stroke

Advanced Science, Volume 12, Issue 13, April 3, 2025.
Using single‐cell sequencing in a murine stroke model (p‐MCAO), three stroke‐specific subpopulations are identified: disease inflammatory macrophage (DIM), disease‐associated microglia (DAM), and CD14+ neutrophils (Neut_Cd14). Detailed analyses reveal that Neut_Cd14 and DIM subtypes are skull‐derived, whereas DAM likely originates from homeostatic ...
Mo Yang, Yixiang Li, Kaibin Shi, Xuezhu Wang, Xiangrong Liu, Xiang Huang, Fu‐Dong Shi, Shaojie Ma, Mingfeng Li, Yilong Wang   +9 more
wiley   +1 more source

Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation

Nature Neuroscience
AbstractPiezo1 regulates multiple aspects of the vascular system by converting mechanical signals generated by fluid flow into biological processes. Here, we find that Piezo1 is necessary for the proper development and function of meningeal lymphatic vessels and that activating Piezo1 through transgenic overexpression or treatment with the chemical ...
Dongwon Choi, Eunkyung Park, Joshua Choi, Renhao Lu, Jin Suh Yu, Chiyoon Kim, Luping Zhao, James Yu, Brandon Nakashima, Sunju Lee, Dhruv Singhal, Joshua P. Scallan, Bin Zhou, Chester J. Koh, Esak Lee, Young-Kwon Hong   +15 more
openaire   +2 more sources

Diagnostic pathology of equine intracranial neoplasms

Equine Veterinary Education, EarlyView.
H. G. Miller, A. Suarez‐Bonnet
wiley   +1 more source

Illustrator‐anatomist‐clinician triad based pedagogical model in anatomy education: An auxiliary resource amidst lack of hands‐on human dissection

Anatomical Sciences Education, Volume 18, Issue 4, Page 386-405, April 2025.
Abstract Adherence to the highest ethical standards is mandatory while handling precious human tissues received through the altruistic act of body donation. In 2019, misconduct at the Body Donation Center in Paris led to its closure. This adversely affected the hands‐on human dissection sessions within the anatomy education program at Université Paris ...
Maud Creze, Sanjib Kumar Ghosh
wiley   +1 more source

Meningeal Lymphatic Vessel Flow Runs Countercurrent to Venous Flow in the Superior Sagittal Sinus of the Human Brain

Tomography, 2018
The recent report of the existence of meningeal lymphatic vessels (MLVs) in human and nonhuman primates used both histology and magnetic resonance imaging (MRI). Many questions about the physiology and function of these lymphatic vessels remain unanswered.
Kuo, Phillip H., Stuehm, Carol, Squire, Scott, Johnson, Kevin   +3 more
openaire   +3 more sources

Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges [PDF]

, 2019
The vertebrate CNS is surrounded by the meninges, a protective barrier comprised of the outer dura mater and the inner leptomeninges, which includes the arachnoid and pial layers.
Barber, M, Benson, BC, Castellan, RFP, Correra, RM, Faro, A, Foti, SC, Goodman, JR, Grieg, A, Hawkins, TA, Iliff, JJ, Lashley, T, Rihel, J, Ruhrberg, C, Shibata-Germanos, S, Trivedi, CA, Weller, RO   +15 more
core  

Drug delivery pathways to the central nervous system via the brain glymphatic system circumventing the blood‐brain barrier

Exploration, Volume 5, Issue 2, April 2025.
The discovery of the glymphatic system has opened up a pathway for drug delivery to the brain by circumventing the blood‐brain barrier, which can effectively improve drug utilization. The methods of drug delivery through the glymphatic system include intrathecal injection, intranasal injection, and delivery through the meningeal lymphatic vessels.
Xiang Wang, Yue Yin, Huaijuan Zhou, Bowen Chi, Ling Guan, Pei Li, Jinhua Li, Yilong Wang   +7 more
wiley   +1 more source