Results 71 to 80 of about 8,221 (187)

Meningeal T cells function in the central nervous system homeostasis and neurodegenerative diseases

Frontiers in Cellular Neuroscience, 2023
Recently, a rising interest is given to neuroimmune communication in physiological and neuropathological conditions. Meningeal immunity is a complex immune environment housing different types of immune cells. Here, we focus on meningeal T cells, possibly
Abdellatif Abbaoui, Abdellatif Abbaoui, Oluwaseun Fatoba, Oluwaseun Fatoba, Toshihide Yamashita, Toshihide Yamashita, Toshihide Yamashita, Toshihide Yamashita   +7 more
doaj   +1 more source

Computational Fluid Dynamic Model Prediction of Enhanced Glymphatic Clearance in Response to Focused Ultrasound‐Mediated Blood‐Brain Barrier Opening

Advanced Science, EarlyView.
Focused ultrasound‐mediated blood‐brain barrier opening (FUS BBBO) for enhanced drug delivery also augments glymphatic clearance. A computational model of an arteriole‐venule pair in the brain offers insight into the underlying biotransport mechanisms responsible for this mass clearance effect.
Ryan A. Gladwell, Delaney G. Fisher, Joshua D. Wythe, Christopher B. Highley, John R. Lukens, Richard J. Price   +5 more
wiley   +1 more source

Topographic anatomy of the head [PDF]

, 2016
Посібник рекомендований для студентів вищих медичних навчальних закладів IV рівня акредитації, які вивчають анатомію людини англійською мовою.This manual is intended for the students of medical higher educational institutions of IV accreditation level ...
Korenkov, Oleksii Volodymyrovych, Tkach, Hennadii Fedorovych, Кореньков, Алексей Владимирович, Кореньков, Олексій Володимирович, Ткач, Геннадий Федорович, Ткач, Геннадій Федорович   +5 more
core  

Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance

Advanced Science, EarlyView.
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan, Yuyu Li, Shuo Chen, Li Zhu, Chenchen Zhou, Jianwei Chen, Shujuan Zou, Xianglong Han   +7 more
wiley   +1 more source

Chronic lymphocytic leukemia and the central nervous system: a clinical and pathological study. [PDF]

, 1996
Chronic lymphocytic leukemia is the most common human leukemia but infrequently causes neurologic symptoms. We have reviewed all previously reported cases of chronic lymphocytic leukemia in the CNS along with three new cases; one patient was diagnosed ...
Cramer, SC, Efird, JT, Glaspy, JA, Louis, DN   +3 more
core   +2 more sources

Functional Assessment of the Dural Lymphatic Vessels Using Dynamic Contrast MRI in Multiple Sclerosis [PDF]

, 2023
BACKGROUND AND PURPOSE: The discovery of glymphatic function in the human brain has generated interest in waste clearance mechanisms in neurological disorders such as multiple sclerosis (MS).
Gabr, Refaat E, Hasan, Khader M, Kramer, Larry A, Lincoln, John A   +3 more
core   +3 more sources

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

Annals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije, Sara T. De Palma, Josine E. G. Vaes, Katiuscia Dallaglio, Giorgia Volpi, Diego Ardigò, Sabine van Rijt, Frank van Bel, Manon J. N. L. Benders, Cora H. A. Nijboer   +9 more
wiley   +1 more source

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain

eLife, 2022
The discovery of meningeal lymphatic vessels that drain the CNS has prompted new insights into how immune responses develop in the brain. In this study, we examined how T cell responses against CNS-derived antigen develop in the context of infection.
Michael A Kovacs, Maureen N Cowan, Isaac W Babcock, Lydia A Sibley, Katherine Still, Samantha J Batista, Sydney A Labuzan, Ish Sethi, Tajie H Harris   +8 more
doaj   +1 more source

Brain interference: Revisiting the role of IFNγ in the central nervous system [PDF]

, 2017
Interferon gamma (IFN-gamma) is a pro-inflammatory cytokine, first described as a secreted molecule capable of interfering with viral replication. Since then, numerous other important actions in the context of the immune response to invading pathogens ...
Cerqueira, João José, Correia-Neves, M, Marques, Fernanda, Monteiro, Susana Isabel Gonçalves, Roque, Susana   +4 more
core   +1 more source

Clinical perspectives and comparisons between immunoglobulin G4‐related disease and antineutrophil cytoplasmic antibody‐associated vasculitis

Rheumatology &Autoimmunity, EarlyView.
Clinical perspectives and comparisons between immunoglobulin G4‐related disease and antineutrophil cytoplasmic antibody‐associated vasculitis. Abstract Both immunoglobulin (Ig) G4‐related disease (IgG4‐RD) and antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) are systemic disorders that affect a wide range of organs.
Wenhuan Zeng, Mingxin Bai, Yanying Liu
wiley   +1 more source