Results 11 to 20 of about 4,490 (191)

Role of the Meningeal Lymphatics in Stroke. [PDF]

Stroke, 2023
Perla M, Caretti V, Moro MA, McCullough LD.   +3 more
europepmc   +9 more sources

The role of the meningeal lymphatic system in local meningeal inflammation and trigeminal nociception [PDF]

Scientific Reports, 2022
A system of lymphatic vessels has been recently characterized in the meninges, with a postulated role in 'cleaning' the brain via cerebral fluid drainage.
Abdollahzadeh, Ali, Eme-Scolan, Elisa, Gafurov, Oleg, Giniatullin, Rashid, Giniatullina, Raisa, Hamalainen, Riikka H., Koroleva, Kseniia, Krivoshein, Georgii, Malm, Tarja, Mikhailov, Nikita, Noe, Francesco M., Rua, Rejane, Sierra, Alejandra, Teleman, Matei, Tohka, Jussi, Virenque, Anais   +15 more
core   +7 more sources

Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective [PDF]

Neuroscience Insights, 2019
The recent discovery of lymphatic vessels in the meningeal layers calls into question the known mechanisms of fluid and macromolecule homeostasis and immunoregulation within the central nervous system.
Korri S Hershenhouse, Orr Shauly, Daniel J Gould, Ketan M Patel   +3 more
doaj   +2 more sources

Impaired Meningeal Lymphatics and Glymphatic Pathway in Patients with White Matter Hyperintensity [PDF]

Advanced Science
White matter hyperintensity (WMH) represents a critical global medical concern linked to cognitive decline and dementia, yet its underlying mechanisms remain poorly understood.
Ying Zhou, Rui Xue, Yifei Li, Wang Ran, Yuping Chen, Zhongyu Luo, Kemeng Zhang, Ruoxia Zhang, Junjun Wang, Mengmeng Fang, Cong Chen, Min Lou   +11 more
doaj   +2 more sources

CSF circulation and dispersion yield rapid clearance from intracranial compartments [PDF]

Frontiers in Bioengineering and Biotechnology, 2022
In this paper, we used a computational model to estimate the clearance of a tracer driven by the circulation of cerebrospinal fluid (CSF) produced in the choroid plexus (CP) located within the lateral ventricles.
Martin Hornkjøl, Lars Magnus Valnes, Geir Ringstad, Geir Ringstad, Marie E. Rognes, Marie E. Rognes, Per-Kristian Eide, Per-Kristian Eide, Kent-André Mardal, Kent-André Mardal, Vegard Vinje   +10 more
doaj   +3 more sources

Photobiomodulation of lymphatic drainage and clearance: perspective strategy for augmentation of meningeal lymphatic functions [PDF]

Biomedical Optics Express, 2020
There is a hypothesis that augmentation of the drainage and clearing function of the meningeal lymphatic vessels (MLVs) might be a promising therapeutic target for preventing neurological diseases.
Abdurashitov, Arkady, Agranovich, Ilana, Blokhina, Inna, Dubrovsky, Alexander, Klimova, Maria, Kurths, Jurgen, Kuznecova, Anna, Lezhnev, Nikita, Rafailov, Edik, Semyachkina-glushkovskaya, Oxana, Shirokov, Alexander, Shnitenkova, Anastassia, Terskov, Andrey, Tuchin, Valery, Vinnik, Valeria   +14 more
core   +5 more sources

Non-invasive modulation of meningeal lymphatics ameliorates ageing and Alzheimer’s disease-associated pathology and cognition in mice [PDF]

Nature Communications
Meningeal lymphatic vessels (mLVs) have been shown to be involved in amyloid beta (Aβ) clearance, which is considered as a potential therapeutic target for Alzheimer’s disease (AD).
Miao Wang, Congcong Yan, Xi Li, Tianhao Yang, Shengnan Wu, Qian Liu, Qingming Luo, Feifan Zhou   +7 more
doaj   +2 more sources

Brain Drain for Brain Gain: Potential Applications of Robotic-assisted Lymphatic Microsurgery in the Management of Neurological Disorders [PDF]

Plastic and Reconstructive Surgery, Global Open
Background:. The central nervous system (CNS) was long believed to be devoid of lymphatic drainage. However, the discovery of the glymphatic system and meningeal lymphatics has revolutionized our understanding of cerebrospinal fluid homeostasis and ...
Jennifer A. Watson, MD, Samuel Knoedler, MD, Donata von Reibnitz, MD, Carmen E. Zurfluh, MD, Carlotta Imholz, MMed, Giuseppe Esposito, MD, PhD, Simon J. Schreiner, MD, Epameinondas Gousopoulos, MD, PhD, Aijia Cai, MD, Sedef Kollarik, PhD, Pietro Giovanoli, MD, Christian Baumann, MD, Nicole Lindenblatt, MD   +12 more
doaj   +2 more sources

Meningeal lymphatic function promotes oligodendrocyte survival and brain myelination [PDF]

Immunity
The precise neurophysiological changes prompted by meningeal lymphatic dysfunction remain unclear. Here, we showed that inducing meningeal lymphatic vessel ablation in adult mice led to gene expression changes in glial cells, followed by reductions in ...
Almeida, Francisco, Barber, Megan J, Cucuzza, Chiara Starvaggi, Da Mesquita, Sandro, das Neves, Sofia P, Delivanoglou, Nickoleta, Faroqi, Ayman H, Irani, Sarosh R, Makuch, Mateusz, McLean, Pamela J, Oliveira, Tiago Gil, Piehl, Fredrik, Rego, Shanon, Ren, Yingxue, Sanchez, Guadalupe, Schrader, Racquelle, Thomas, Jean-Leon   +16 more
core   +5 more sources

Visualising and semi-quantitatively measuring brain fluid pathways, including meningeal lymphatics, in humans using widely available MRI techniques. [PDF]

J Cereb Blood Flow Metab, 2023
Sennfält S, Thrippleton MJ, Stringer M, Reyes CA, Chappell F, Doubal F, Garcia DJ, Zhang J, Cheng Y, Wardlaw J.   +9 more
europepmc   +4 more sources