Results 31 to 40 of about 4,490 (191)
New insight into DAVF pathology—Clues from meningeal immunity
Frontiers in Immunology, 2022 In recent years, with the current access in techniques, studies have significantly advanced the knowledge on meningeal immunity, revealing that the central nervous system (CNS) border acts as an immune landscape.
Tianqi Tu +8 more
doaj +1 more source
Neuroinflammation-Driven Lymphangiogenesis in CNS Diseases
Frontiers in Cellular Neuroscience, 2021 The central nervous system (CNS) undergoes immunosurveillance despite the lack of conventional antigen presenting cells and lymphatic vessels in the CNS parenchyma. Additionally, the CNS is bathed in a cerebrospinal fluid (CSF).
Martin Hsu +3 more
doaj +1 more source
Frontiers in Immunology, 2023 In recent decades there has been a large focus on understanding the mechanisms of peripheral immune cell infiltration into the central nervous system (CNS) in neuroinflammatory diseases.
Collin Laaker +4 more
doaj +1 more source
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis [PDF]
The Journal of Immunology, 2020 Abstract Traumatic brain injury (TBI) has emerged as a leading cause of death and disability. Despite being a growing medical issue, the biological factors that promote central nervous system (CNS) pathology and neurological dysfunction following TBI remain poorly characterized.
Ashley C. Bolte +12 more
openaire +4 more sources
Stroke: Vascular and Interventional Neurology, 2021 Introduction: Until recently, there was very little known about the brain’s waste removal system. Unlike the peripheral organ systems, the CNS lacked a clearly defined lymphatic vasculature and waste clearance mechanism.
Richard Pham, Rano Chatterjee
doaj +1 more source
The cervical lymph node contributes to peripheral inflammation related to Parkinson’s disease
Journal of Neuroinflammation, 2023 Background Peripheral inflammation is an important feature of Parkinson’s disease (PD). However, if and how CNS pathology is involved in the peripheral inflammation in PD remains to be fully investigated.
Zongran Liu +6 more
doaj +1 more source
Functional Assessment of the Dural Lymphatic Vessels Using Dynamic Contrast MRI in Multiple Sclerosis [PDF]
, 2023 BACKGROUND AND PURPOSE: The discovery of glymphatic function in the human brain has generated interest in waste clearance mechanisms in neurological disorders such as multiple sclerosis (MS).
Gabr, Refaat E +3 more
core +5 more sources
Charting the meningeal lymphatic network
Journal of Experimental Medicine, 2022 A genuine network of lymphatic vessels can be found in the dural layer of the meninges that ensheathe the brain and spinal cord of mammalians. In this issue, Jacob et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20220035) employ light sheet fluorescence imaging of intact mouse heads to provide a more comprehensive chart of the meningeal lymphatic
openaire +2 more sources
Development and plasticity of meningeal lymphatic vessels [PDF]
Journal of Experimental Medicine, 2017 The recent discovery of meningeal lymphatic vessels (LVs) has raised interest in their possible involvement in neuropathological processes, yet little is known about their development or maintenance. We show here that meningeal LVs develop postnatally, appearing first around the foramina in the basal parts of the skull and spinal canal, sprouting along
Aspelund Aleksanteri +19 more
openaire +3 more sources
Investigation of CSF outflow in mice by in vivo, dynamic magnetic resonance imaging [PDF]
, 2022 The anatomical routes for the clearance of cerebrospinal fluid (CSF) remain incompletely understood. However, recent evidence has given strong support for routes leading to lymphatic vessels. A current debate centers upon the routes through which CSF can
Krämer, Jonas Uwe
core +1 more source