Results 21 to 30 of about 1,149,764 (218)
Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase). [PDF]
PLoS ONE, 2009 Deliberate and natural outbreaks of infectious disease underscore the necessity of effective vaccines and antimicrobial/antiviral therapeutics. The prevalence of antibiotic resistant strains and the ease by which antibiotic resistant bacteria can be ...
Safdar Jawaid +7 more
doaj +1 more source
MEP Pathway: First-Synthesized IspH-Directed Prodrugs with Potent Antimycobacterial Activity. [PDF]
MicroorganismsWe report the first synthesis of IspH-directed prodrugs targeting the terminal enzyme of the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (IspH or LytB).
Allamand A +5 more
europepmc +2 more sources
Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. [PDF]
PLoS ONE, 2012 Salvia miltiorrhiza has been widely used in the treatment of coronary heart disease. Tanshinones, a group of diterpenoids are the main active ingredients in S. miltiorrhiza.
Dongfeng Yang +7 more
doaj +1 more source
Bioengineering, 2023 Astaxanthin is a powerful antioxidant and is used extensively as an animal feed additive and nutraceutical product. Here, we report the use of the β-carotene hydroxylase (CBFD1) and the β-carotene ketolase (HBFD1) from Adonis aestivalis, a flowering ...
Jared H. Roth, Valerie C. A. Ward
doaj +1 more source
Identification of target genes of the bZIP transcription factor OsTGAP1, whose overexpression causes elicitor-induced hyperaccumulation of diterpenoid phytoalexins in rice cells. [PDF]
PLoS ONE, 2014 Phytoalexins are specialised antimicrobial metabolites that are produced by plants in response to pathogen attack. Momilactones and phytocassanes are the major diterpenoid phytoalexins in rice and are synthesised from geranylgeranyl diphosphate, which is
Koji Miyamoto +8 more
doaj +1 more source
Frontiers in Plant Science, 2019 Chloroplasts are essential for autonomous plant growth, and their biogenesis is a complex process requiring both plastid and nuclear genome. One of the essential factors required for chloroplast biogenesis are carotenoids.
Eva Vranová +3 more
doaj +1 more source
Handbook for safe and ethical peer mentoring with women surviving domestic abuse
A handbook and associated policy documents for Pathway Project, Lichfield, Staffordshire. including process, confidentiality statement and processes to be followed when acting as a volunteer peer mentoring with women surviving domestic ...
Pathway Project, Lichfield +1 more
core +4 more sources
Plants, 2020 The Madagascar periwinkle (Catharanthus roseus) synthesizes the highly valuable monoterpene indole alkaloids (MIAs) through a long metabolic route initiated by the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway. In leaves, a complex compartmentation of
Grégory Guirimand +14 more
doaj +1 more source
MEP-rc, SICI, and IHI measures.
, 2018 MEP-rc (A), SICI (B), and IHI (B) measures Pre- and Post- motor training are shown for the Val66Val Vs. the Vall6Met groups in the Experiment 1. The error bars represent standard errors of the mean. Dashed lines used for comparisons show simple effects. *
Jean-Marc Therrien-Blanchet (3600248) +3 more
core +2 more sources
Frontiers in Plant Science, 2022 It is critical to develop plant isoprenoid production when dealing with human-demanded industries such as flavoring, aroma, pigment, pharmaceuticals, and biomass used for biofuels.
Ali Movahedi +11 more
doaj +1 more source