De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis. [PDF]
, 2015 BackgroundBixin or annatto is a commercially important natural orange-red pigment derived from lycopene that is produced and stored in seeds of Bixa orellana L.
Aguilar-Espinosa, Margarita +5 more
core +3 more sources
Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots. [PDF]
PLoS ONE, 2012 Salvia miltiorrhiza has been widely used in the treatment of coronary heart disease. Tanshinones, a group of diterpenoids are the main active ingredients in S. miltiorrhiza.
Dongfeng Yang +7 more
doaj +1 more source
Bioengineering, 2023 Astaxanthin is a powerful antioxidant and is used extensively as an animal feed additive and nutraceutical product. Here, we report the use of the β-carotene hydroxylase (CBFD1) and the β-carotene ketolase (HBFD1) from Adonis aestivalis, a flowering ...
Jared H. Roth, Valerie C. A. Ward
doaj +1 more source
Mathematical modelling of the diurnal regulation of the MEP pathway in Arabidopsis.
New Phytologist, 2015 Summary Isoprenoid molecules are essential elements of plant metabolism. Many important plant isoprenoids, such as chlorophylls, carotenoids, tocopherols, prenylated quinones and hormones are synthesised in chloroplasts via the 2‐C‐methyl‐d‐erythritol 4‐phosphate (MEP) pathway.
A. Pokhilko +4 more
semanticscholar +4 more sources
The MEP-pathway genes are polyphyletic origin and evolutionary conserved [PDF]
, 2020 Abstract BackgroundIsoprenoids are amongst the most ancient and essential class of metabolites produced in all organisms, either via mevalonate (MVA)-and/or methylerythritol dicyclophosphate (MEP)-pathways. The MEP-pathway is present in all plastid-bearing organisms and most eubacteria.
Liping Zeng, Katayoon Dehesh
openaire +1 more source
Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites. [PDF]
PLoS PathogA proposed treatment for malaria is a combination of fosmidomycin and clindamycin. Both compounds inhibit the methylerythritol 4-phosphate (MEP) pathway, the parasitic source of farnesyl and geranylgeranyl pyrophosphate (FPP and GGPP, respectively). Both FPP and GGPP are crucial for the biosynthesis of several essential metabolites
Crispim M +10 more
europepmc +5 more sources
The plastidial MEP pathway: unified nomenclature and resources
Trends in Plant Science, 2008 In plants, the plastid-localized 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway provides the precursors for the synthesis of isoprenoid hormones, monoterpenes, carotenoids and the side chain of chlorophylls, tocopherols and prenylquinones. As a result of the fast progress in the elucidation and characterization of the pathway (mainly by genetic ...
Phillips, Michael +3 more
openaire +3 more sources
Identification of target genes of the bZIP transcription factor OsTGAP1, whose overexpression causes elicitor-induced hyperaccumulation of diterpenoid phytoalexins in rice cells. [PDF]
PLoS ONE, 2014 Phytoalexins are specialised antimicrobial metabolites that are produced by plants in response to pathogen attack. Momilactones and phytocassanes are the major diterpenoid phytoalexins in rice and are synthesised from geranylgeranyl diphosphate, which is
Koji Miyamoto +8 more
doaj +1 more source
Cerebellum to motor cortex paired associative stimulation induces bidirectional STDP-like plasticity in human motor cortex [PDF]
, 2012 The cerebellum is crucially important for motor control and adaptation. Recent non-invasive brain stimulation studies have indicated the possibility to alter the excitability of the cerebellum and its projections to the contralateral motor cortex, with ...
Lu, Ming-Kuei +2 more
core +1 more source
Designing a competency based program to facilitate the progression of experienced engineering technologists to professional engineer status [PDF]
, 2006 This paper describes the pedagogical principles that underpin the design of the Master of Engineering Practice, a distance education program offered by the University of Southern Queensland.
Dowling, David
core +2 more sources