Results 51 to 60 of about 3,014,380 (256)

Investigating Novel IspE Inhibitor of MEP Pathway in Mycobacterium

, 2023
In a recent effort to mitigate harm from human pathogens, many biosynthetic pathways are extensively evaluated for their ability to inhibit pathogen growth and determine drug targets. Among those, one of the important products/targets of such pathways is isopentenyl diphosphate, the universal precursor of isoprenoids, which are essential for the normal
Seoung-ryoung Choi, Prabagaran Narayanasamy   +1 more
openaire   +1 more source

Current Dissipation in Thin Superconducting Wires: Accurate Numerical Evaluation Using the String Method [PDF]

, 2005
Current dissipation in thin superconducting wires is numerically evaluated by using the string method, within the framework of time-dependent Ginzburg-Landau equation with a Langevin noise term.
Ping Sheng, Tiezheng Qian, W. Ren, Weiqing Ren   +3 more
core   +2 more sources

Determination of the active stereoisomer of the MEP pathway-targeting antimalarial agent MMV008138, and initial structure-activity studies.

Bioorganic and Medicinal Chemistry Letters, 2015
Zhong-Ke Yao, Priscilla M Krai, E. Merino, M. Simpson, C. Slebodnick, M. Cassera, P. Carlier   +6 more
semanticscholar   +3 more sources

Genome-Wide Association Study and Pathway-Level Analysis of Kernel Color in Maize. [PDF]

, 2019
Rapid development and adoption of biofortified, provitamin A-dense orange maize (Zea mays L.) varieties could be facilitated by a greater understanding of the natural variation underlying kernel color, including as it relates to carotenoid biosynthesis ...
Diepenbrock, Christine H, Gore, Michael A, Mateos-Hernandez, Maria, Mathew, Deepu, Owens, Brenda F, Rocheford, Torbert, Tiede, Tyler, Wu, Di   +7 more
core   +2 more sources

Cellular and Subcellular Compartmentation of the 2C-Methyl-D-Erythritol 4-Phosphate Pathway in the Madagascar Periwinkle

Plants, 2020
The Madagascar periwinkle (Catharanthus roseus) synthesizes the highly valuable monoterpene indole alkaloids (MIAs) through a long metabolic route initiated by the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway. In leaves, a complex compartmentation of
Grégory Guirimand, Anthony Guihur, Catalina Perello, Michael Phillips, Samira Mahroug, Audrey Oudin, Thomas Dugé de Bernonville, Sébastien Besseau, Arnaud Lanoue, Nathalie Giglioli-Guivarc’h, Nicolas Papon, Benoit St-Pierre, Manuel Rodríguez-Concepcíon, Vincent Burlat, Vincent Courdavault   +14 more
doaj   +1 more source

Isoprenoid biosynthesis regulation in poplars by methylerythritol phosphate and mevalonic acid pathways

Frontiers in Plant Science, 2022
It is critical to develop plant isoprenoid production when dealing with human-demanded industries such as flavoring, aroma, pigment, pharmaceuticals, and biomass used for biofuels.
Ali Movahedi, Hui Wei, Boas Pucker, Mostafa Ghaderi-Zefrehei, Fatemeh Rasouli, Fatemeh Rasouli, Ali Kiani-Pouya, Ali Kiani-Pouya, Tingbo Jiang, Qiang Zhuge, Liming Yang, Xiaohong Zhou   +11 more
doaj   +1 more source

Nudged-elastic band method with two climbing images: finding transition states in complex energy landscapes [PDF]

, 2014
The nudged-elastic band (NEB) method is modified with concomitant two climbing images (C2-NEB) to find a transition state (TS) in complex energy landscapes, such as those with serpentine minimal energy path (MEP).
Johnson, Duane, Johnson, Duane, Zarkevich, Nikolai, Zarkevich, Nikolai   +3 more
core   +4 more sources

Task‐specific strength increases after lower‐limb compound resistance training occurred in the absence of corticospinal changes in vastus lateralis [PDF]

, 2020
Neural adaptations subserving strength increases have been shown to be task‐specific, but responses and adaptation to lower‐limb compound exercises such as the squat are commonly assessed in a single‐limb isometric task.
Angius, Luca, Ansdell, Paul, Brownstein, Callum, Durbaba, Rade, Frazer, Ashlyn, Goodall, Stuart, Hicks, Kirsty, Howatson, Glyn, Kidgell, Dawson, Thomas, Kevin, Škarabot, Jakob   +10 more
core   +2 more sources

SEED CAROTENOID DEFICIENT Functions in Isoprenoid Biosynthesis via the Plastid MEP Pathway [PDF]

Plant Physiology, 2019
Plastid isoprenoids, a diverse group of compounds that includes carotenoids, chlorophylls, tocopherols, and multiple hormones, are essential for plant growth and development. Here, we identified and characterized SEED CAROTENOID DEFICIENT (SCD), which encodes an enzyme that functions in the biosynthesis of plastid isoprenoids in maize (Zea mays).
Lili Zhang, Xuan Zhang, Xiaoji Wang, Jing Xu, Min Wang, Lin Li, Guanghong Bai, Hui Fang, Shuting Hu, Jigang Li, Jianbing Yan, Jiansheng Li, Xiaohong Yang   +12 more
openaire   +2 more sources

Surface and interstitial Ti diffusion at the rutile TiO2(110) surface [PDF]

, 2010
Diffusion of Ti through the TiO2 (110) rutile surface plays a key role in the growth and reactivity of TiO2. To understand the fundamental aspects of this important process, we present an analysis of the diffusion of Ti adspecies at the stoichiometric ...
Anisimov, Bennett, Bennett, Bennett, Bennett, Blöchl, Bowker, Bowker, C. S. Browne, Cuong, Di Valentin, Di Valentin, Diebold, Dubrovinsky, Dudarev, E. Sanville, Finazzi, Hallil, Hallil, Henderson, Henkelman, Iddir, Kresse, Kresse, Kresse, M. Basham, M. Nolan, Marezio, Morgan, Mulheran, Nolan, Onishi, P. A. Mulheran, Pentcheva, Poteryaev, R. A. Bennett, Rappe, Rohrer, Rohrer, Sanville, Sanville, Smith, Stone, Swamy, Swamy, Thomas, Thomas, Wendt, Yim, Zhang, Zhou   +50 more
core   +1 more source