Results 71 to 80 of about 37,289 (232)
Journal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto +6 more
wiley +1 more source
Cancer ReportsBackground Mercaptopurine is an important component of acute lymphoblastic leukemia (ALL) and lymphoma (LLy) maintenance therapy. The 6‐thioguanine nucleosides (6‐TGN) are believed to be the primary contributor to myelosuppression and immunosuppressive ...
Tecca Barone +3 more
doaj +1 more source
Frontiers in OncologyIntroductionPolymorphisms in NUDT15 may result in differences in mercaptopurine-induced toxicity. This study aimed to identify the frequency of the NUDT15 (c.415C>T; rs116855232) polymorphism and investigate the effect of this polymorphism on ...
Muhammad Muhammad +7 more
doaj +1 more source
Liver dysfunction in patients with IBD under immunosuppressive treatment: do we need to fear? [PDF]
, 2010 International ...
Beaugerie, Laurent, Gerbes, Alexander L.
core +3 more sources
Aggregate, Volume 7, Issue 2, February 2026.The integration of metal nanoclusters (MNCs) with reticular frameworks (RFs) has recently emerged as a powerful strategy to create composite materials with enhanced and synergistic functionalities. This review provides an overview of the synthetic strategies developed for constructing MNCs/RFs composites and their recent advances in biomedical ...
Wenfeng Liu +3 more
wiley +1 more source
Induction of Mineralization [PDF]
, 2014 Vascular mineralization contributes to the high cardiovascular morbidity and mortality in patients who suffer from chronic kidney disease and in individuals who have undergone solid organ transplantation. The immunosuppressive regimen used to treat these
Giet, Markus van der +6 more
core +1 more source
Design and development of hydrogel nanoparticles for mercaptopurine
Journal of Advanced Pharmaceutical Technology & Research, 2010 Hydrogel nanoparticles have gained attention in recent years as they demonstrate the features and characters of hydrogels and nanoparticles at the same time.
V Senthil +5 more
doaj +1 more source
Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes [PDF]
, 2014 Aim: We investigated candidate genes associated with thiopurine metabolism and clinical response in childhood acute lymphoblastic leukemia. Materials & methods: We performed genome-wide SNP association studies of 6-thioguanine and 6-mercaptopurine ...
Batzler, A. +10 more
core +1 more source
A Case of Drug‐Induced Pancreatitis
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Drug‐induced pancreatitis (DIP) is a rare but important cause of acute abdominal pain, and ciprofloxacin‐associated cases are exceptionally uncommon. We report a 35‐year‐old woman with no significant medical history who developed severe epigastric pain radiating to the back, accompanied by nausea and vomiting, 3 days after initiating self ...
Muskan Shrestha +5 more
wiley +1 more source
Azathioprine in inflammatory bowel disease, a safe alternative?
Mediators of Inflammation, 1998 Azathioprine and its metabolite 6-mercaptopurine are effective in the treatment of inflammatory bowel disease. They are mostly used for reduction of the use of steroids, maintenance therapy after remission induction by cyclosporin and treatment of ...
A. A. Tanis
doaj +1 more source