Results 71 to 80 of about 20,809 (211)

Salivary Methotrexate as a Predictor of Oral Mucositis in Hematological Cancer Patients: A Phase II Randomized, Double‐Blind Clinical Trial

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To evaluate the efficacy of prophylactic photobiomodulation therapy (PBMT) in preventing oral mucositis (OM) and to assess serum and salivary methotrexate (MTX) levels as predictors of OM in adults receiving high‐dose methotrexate (HD‐MTX).
Letícia Rodrigues‐Oliveira   +21 more
wiley   +1 more source

RESISTANCE TO 6-MERCAPTOPURINE: III. DELETION OF A 5′-NUCLEOTIDASE IN A 6-MERCAPTOPURINE-RESISTANT SUBLINE OF THE EHRLICH ASCITES CARCINOMA

open access: yes, 1963
Nuclei prepared from cells of a 6-mercaptopurine-resistant subline of the Ehrlich ascites carcinoma differed from nuclei isolated from the parent line of cells in being markedly deficient in an enzymatic activity, 5′-nucleotidase.The nucleotidase ...
A. Hori, A. R. P. Paterson
core   +1 more source

TNFSF14/LIGHT responses in intestinal and oesophageal fibroblasts are differentially modulated by hydroxylase inhibitors

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck   +13 more
wiley   +1 more source

Impact of Consciousness Energy Healing Treatment on the Physicochemical and Thermal Properties of an Anticancer Drug 6-Mercaptopurine

open access: yes, 2019
Mercaptopurine is an antineoplastic chemotherapy drug is used for the treatment of cancer, Crohn's disease, ulcerative colitis, autoimmune diseases, etc.
Jana, Snehasis   +4 more
core   +1 more source

Chemoprevention of electrophilic damage by mercaptopurine analogs [PDF]

open access: yes, 1990
Analogs of 6-mercaptopurine have been found to enhance the detoxification of various electrophilic toxicants in vivo, while having minimal cytotoxicity themselves.
MacLeod, Michael C.
core   +1 more source

Azathioprine in inflammatory bowel disease, a safe alternative?

open access: yesMediators of Inflammation, 1998
Azathioprine and its metabolite 6-mercaptopurine are effective in the treatment of inflammatory bowel disease. They are mostly used for reduction of the use of steroids, maintenance therapy after remission induction by cyclosporin and treatment of ...
A. A. Tanis
doaj   +1 more source

Optimization and validation of an RP-HPLC method for the estimation of 6-mercaptopurine in bulk and pharmaceutical formulations

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2014
A reverse phase HPLC method is described for the determination of 6-mercaptopurine in bulk and tablets. Chromatography was carried on a C18 column using a mixture of acetonitrile and 0.05 mol/L sodium acetate buffer (10:90 v/v) as the mobile phase at a ...
Vanita Somasekhar
doaj   +1 more source

Hair loss in pediatric inflammatory bowel disease: Clinical recognition and implications for care

open access: yes
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Angela Anaeme   +2 more
wiley   +1 more source

MERCAPTOPURINE AND SILYLATED MERCAPTOPURINE IN THE TREATMENT OF THE EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

open access: yes, 1990
VOHL ML, WESTARP ME, WEKERLE H, GERLACH M, Jutzi P, PRZUNTEK H. MERCAPTOPURINE AND SILYLATED MERCAPTOPURINE IN THE TREATMENT OF THE EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS. ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH.
VOHL, ML   +5 more
core  

A New Electrochemical Sensor for Direct Detection of Purine Antimetabolites and DNA Degradation

open access: yesJournal of Analytical Methods in Chemistry, 2019
The development of a reliable electrochemical sensor using a hybrid nanocomposite consisting of ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate) functionalized graphene oxide (GrO-IL) and gold nanoparticles (AuNPs) stabilized by chitosan ...
Liliya K. Shpigun, Elena Yu. Andryukhina
doaj   +1 more source

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