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Merkel cell polyomavirus and associated Merkel cell carcinoma [PDF]

open access: yesTumour Virus Research, 2022
Merkel cell polyomavirus (MCPyV) is a ubiquitous skin infection that can cause Merkel cell carcinoma (MCC), a highly lethal form of skin cancer with a nearly 50% mortality rate.
June F. Yang, Jianxin You
doaj   +4 more sources

Merkel cell polyomavirus and its etiological relationship with skin tumors [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2023
Viruses have been frequently identified in several human neoplasms, but the etiological role of these viruses in some tumors is still a matter of controversy.
Thiago Rubim Bellott   +5 more
doaj   +2 more sources

Temporal gating of nuclear import: How Merkel cell polyomavirus exploits the cell cycle for nuclear entry. [PDF]

open access: yesPLoS Pathogens
Merkel cell polyomavirus (MCPyV) is a small, DNA tumor virus that is causally linked to an aggressive form of human skin cancer called Merkel cell carcinoma. MCPyV is the only polyomavirus definitively shown to cause cancer in humans, yet little is known
Karen Wang   +4 more
doaj   +2 more sources

Merkel Cell Polyomavirus: Oncogenesis in a Stable Genome [PDF]

open access: yesViruses, 2021
Merkel cell polyomavirus (MCV) is the causative agent for the majority of Merkel cell carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the integration of MCV DNA into the tumor genome and a low tumor mutational burden.
Mona M. Ahmed   +2 more
doaj   +2 more sources

Serum antibodies against mimotopes of Merkel cell polyomavirus oncoproteins detected by a novel immunoassay in healthy individuals and Merkel cell carcinoma patients [PDF]

open access: yesMicrobial Biotechnology
Merkel cell polyomavirus (MCPyV) is the foremost causative factor of Merkel cell carcinoma (MCC), a rare yet highly aggressive skin cancer. Although the evaluation of circulating IgG antibodies against Merkel cell polyomavirus (MCPyV) LT/sT oncoproteins ...
Chiara Mazziotta   +12 more
doaj   +2 more sources

Merkel cell carcinoma in an immunosuppressed patient [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2017
Merkel cell carcinoma is an uncommon neuroendocrine carcinoma with a rising incidence and an aggressive behavior. It predominantly occurs in older patients, with onset occurring at a mean age of 75-80 years.
Heliana Freitas de Oliveira Góes   +5 more
doaj   +1 more source

Serological cross-reactivity between Merkel cell polyomavirus and two closely related chimpanzee polyomaviruses. [PDF]

open access: yesPLoS ONE, 2014
Phylogenetic analyses based on the major capsid protein sequence indicate that Merkel cell polyomavirus (MCPyV) and chimpanzee polyomaviruses (PtvPyV1, PtvPyV2), and similarly Trichodysplasia spinulosa-associated polyomavirus (TSPyV) and the orangutan ...
Jérôme T J Nicol   +6 more
doaj   +1 more source

Merkel cell carcinoma arising from postoperative scar: An unusual presentation

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2021
Merkel cell carcinoma (MCC) is an aggressive and uncommon primary cutaneous neuroendocrine cancer. With unknown pathogenesis, immunosuppression, ultraviolet radiation, Merkel cell polyomavirus, and arsenic exposure are the risk factors.
Mualla Polat   +4 more
doaj   +1 more source

Primary Merkel cell carcinoma of the salivary gland: a clinicopathologic study of four cases with a review of literature [PDF]

open access: yesJournal of Pathology and Translational Medicine
Background Primary Merkel cell carcinoma of the salivary gland is currently not listed in the World Health Organization classification. However, cases of Merkel cell type neuroendocrine carcinomas of the salivary gland with perinuclear cytokeratin 20 ...
Gyuheon Choi   +6 more
doaj   +1 more source

Newly described human polyomaviruses Merkel Cell, KI and WU are present in urban sewage and may represent potential environmental contaminants

open access: yesVirology Journal, 2010
Recently, three new polyomaviruses (KI, WU and Merkel cell polyomavirus) have been reported to infect humans. It has also been suggested that lymphotropic polyomavirus, a virus of simian origin, infects humans. KI and WU polyomaviruses have been detected
Carratala Anna   +4 more
doaj   +1 more source

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