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Antiviral Chlorinated Drimane Meroterpenoids from the Fungus Talaromyces pinophilus LD-7 and Their Biosynthetic Pathway.

Journal of Natural Products
Ten new drimane meroterpenoids talarines A-J (1-10), along with six known analogues (11-16), were isolated from desert soil-derived fungus Talaromyces pinophilus LD-7. Their 2D structures were elucidated by comprehensive interpretation of NMR and HRESIMS
Meng Ren   +9 more
semanticscholar   +1 more source

Enantiomeric pairs of meroterpenoids from Rhododendron fastigiatum

Chinese Journal of Natural Medicines, 2019
Five pairs of optically pure meroterpenoid enantiomers (1a/1b-5a/5b) and two known compounds (6 and 7) were isolated from Rhododendron fastigiatum. Compounds 1a/1b-5a/5b were resolved from naturally scalemic mixtures by chiral HPLC. Their structures were elucidated by spectroscopic methods, X-ray crystallographic experiments, and ECD analyses ...
Guang-Hui, Huang   +5 more
openaire   +2 more sources

Arenarialins A-F, Anti-inflammatory Meroterpenoids with Rearranged Skeletons from the Marine Sponge Dysidea arenaria.

Journal of Natural Products
Six new sesquiterpene quinone/hydroquinone meroterpenoids, arenarialins A-F (1-6), were isolated from the marine sponge Dysidea arenaria collected from the South China Sea. Their chemical structures and absolute configurations were determined by HRMS and
Jia-xin Li   +7 more
semanticscholar   +1 more source

Renoprotective meroterpenoids from the fungus Ganoderma cochlear

Fitoterapia, 2019
Nine multifarious new meroterpenoids, cochlearols E-M (1-9), along with seven known meroterpenoids 10-16, were isolated from the fruiting bodies of Ganoderma cochlear. Racemic 1, 6-8, 10 and 13 were separated by chiral HPLC. The structures were elucidated based on detailed spectroscopic analyses (HRESIMS, 1D/2D-NMR) and calculated electronic circular ...
Xin-Long, Wang   +5 more
openaire   +2 more sources

Discovery, biosynthesis, organic synthesis, and bioactivities of meroterpenoids from Rhododendron species.

Phytochemistry
Meroterpenoids discovered in Rhododendrons species possess unique chemical structures and biological activities and are expected to become new drug targets for Alzheimer's disease, metabolic disorders, and chronic kidney disease, and these compounds have
Yi Deng   +4 more
semanticscholar   +1 more source

Neuroinhibitory meroterpenoid compounds from Cordia oncocalyx

Fitoterapia, 2017
Five new meroterpenoid compounds designed as rel-10β,11β-epoxy-2,11-dimethoxy-8α-hydroxy-8aβ-methyl-5α,6,7,8,8a,9,10,10aβ-octahydro-1,4-anthracendione (1), rel-10β,11β-epoxy-8α,5-dihydroxy-2-methoxy-8aβ-methyl-5,6,7,8,8a,9,10,10aβ-octahydro -1.4-anthracendione (2), rel-1,4,8α-trihydroxy-5-furanyl-2-methoxy-8aβ-methyl-6,7,8, 8a,9,10-hexahydro-10 ...
Taynara S, Matos   +11 more
openaire   +2 more sources

Structurally diverse chromane meroterpenoids from Rhododendron capitatum with multifunctional neuroprotective effects.

European journal of medicinal chemistry
Eleven new chromane meroterpenoids (1-11), along with 24 known ones (12-35) were isolated from Rhododendron capitatum, a Tibetan medicine. Their structures were determined via extensive spectroscopic methods.
Ye-Fan Shi   +6 more
semanticscholar   +1 more source

Ganospirones A-G, seven undescribed spiro-meroterpenoids from Ganoderma lucidum and their biological activities.

Phytochemistry
Ganoderma lucidum, a medicinal mushroom with a long history in traditional Chinese medicine, is widely used for chronic diseases. Ganospirones A-G (1-7), seven pairs of undescribed spiro-meroterpenoids, were isolated from the fruiting bodies of G ...
Dan Li   +4 more
semanticscholar   +1 more source

Congested heptacyclic meroterpenoids with anti-SARS-CoV-2 and anti-inflammatory activities from mangrove endophytic fungus Talaromyces amestolkiae SCNU-F0041.

Phytochemistry
Under the guidance of LC‒MS/MS-based molecular networking, three previously undescribed berkeleyacetal type meroterpenoids, amestolknoids A-C (1-3), together with ten known analogues (4-13) were isolated and identified from the mangrove endophytic fungus
Jialin Li   +7 more
semanticscholar   +1 more source

Hyperlanins A and B, Two Highly Rearranged Meroterpenoids from Hypericum lancasteri

Chinese journal of chemistry
Hyperlanins A (1) and B (2), two highly rearranged polycyclic polyprenylated acylphloroglucinol (PPAP)‐related meroterpenoids based on different new carbon skeletons, were isolated from Hypericum lancasteri. Compound 1 incorporates an unprecedented 5/6/7/
Jin‐Qiu You   +7 more
semanticscholar   +1 more source

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