Results 11 to 20 of about 2,271 (197)
Progress in the Chemistry of Macrocyclic Meroterpenoids [PDF]
Plants, 2020 In the last decade, the chemistry of meroterpenoids—conjugated molecules formed from isoprenyl fragments through biosynthetic pathways—has developed rapidly.
Dmitriy N. Shurpik +4 more
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Peculiarities of meroterpenoids and their bioproduction
Applied Microbiology and Biotechnology, 2021 Meroterpenoids are a class of terpenoid-containing hybrid natural products with impressive structural architectures and remarkable pharmacological activities. Remarkable advances in enzymology and synthetic biology have greatly contributed to the elucidation of the molecular basis for their biosynthesis.
Jianying Han +5 more
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A modular synthesis of tetracyclic meroterpenoid antibiotics [PDF]
Nature Communications, 2017 Polycyclic meroterpenoids show a wide range of biological activities. Here, the authors report a modular approach to synthesize a number of natural and non-natural tetracyclic meroterpenoids, which display antibiotic activity against methicillin ...
Raphael Wildermuth +6 more
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A radical approach to diverse meroterpenoids [PDF]
Nature Chemistry, 2020 Meroterpenoids are mixed terpenoid–polyketide natural products with a variety of biological activities. Now, a synthetic approach that combines biocatalytic oxidation with a range of other radical-based reactions enables the divergent synthesis of eight oxidized meroterpenoid natural products and one analogue.
Gomm, A, Nelson, A
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Meroterpenoids? A historical and critical review of this biogenetic determinant
Natural Product Reports, 2023 The word meroterpenoid was introduced by Conforth to qualify a biosynthetic pathway. Its use as natural products is at the origin of exclusions and confusions which are discussed here.
Goyer, Eddy +2 more
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Progress in studies on meroterpenoids
, 2020 © 2020 Elsevier B.V. Current developments in the pharmaceutical industry indicate an increase in attention towards natural products and their analogues.
Akhmedov A. +4 more
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Biomimetic Total Synthesis of the Rubiginosin Meroterpenoids
Organic Letters, 2020 Total synthesis of the Rhododendron meroterpenoids rubiginosins A and G, which both contain unusual 6-6-6-4 ring systems, has been achieved using a bioinspired cascade approach. Stepwise synthesis of these natural products, and the related 6-6-5-4 meroterpenoids fastinoid B and rhodonoid B, from naturally occurring chromene precursors is also reported.
Laura Burchill +3 more
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Molecules, 2019 Five new meroterpenoids, zizhines P-S and U (1−4,7), together with two known meroterpenoids (5 and 6) were isolated from Ganoderma sinensis. Their structures including absolute configurations were assigned by using spectroscopic, computational, and
Yan-Jiao Yin +7 more
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Ganoderma lucidum-Derived Meroterpenoids Show Anti-Inflammatory Activity In Vitro
MoleculesGanoderma lucidum, known as the “herb of spiritual potency”, is used for the treatment and prevention of various diseases, but the responsible constituents for its therapeutic effects are largely unknown.
Yun-Yun Liu +3 more
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Production of non-natural 5-methylorsellinate-derived meroterpenoids in Aspergillus oryzae
Beilstein Journal of Organic ChemistryFungal meroterpenoids are diverse structurally intriguing molecules with various biological properties. One large group within this compound class is derived from the aromatic precursor 3,5-dimethylorsellinic acid (DMOA).
Jia Tang, Yixiang Zhang, Yudai Matsuda
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