Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025). [PDF]
Chem BiodiversThis review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Tang Y +6 more
europepmc +2 more sources
Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation. [PDF]
Adv Sci (Weinh)Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Waltl L +20 more
europepmc +2 more sources
BACE1 Inhibitory Meroterpenoids from Aspergillus terreus
, 2018 Sixteen 3,5-dimethylorsellinic acid–based (DMOA-based) meroterpenoids, including 10 new compounds, asperterpenes D–M (1–10), were obtained from Aspergillus terreus.
Xiao-Nian Li (1261545) +14 more
core +7 more sources
Biomimetic Synthesis of Seven Halenaquinone Meroterpenoids. [PDF]
J Am Chem SocStructurally similar natural products arising in phylogenetically distant organisms may reflect convergent evolutionary pressure toward privileged biological scaffolds. The marine sponge-derived halenaquinone meroterpenoids exemplify this phenomenon, sharing a highly electrophilic and strained diketofuran motif with both the viridin/wortmannin and ...
Hart JD +8 more
europepmc +4 more sources
Scalable, Divergent Synthesis of Meroterpenoids via “Borono-sclareolide”
, 2016 A scalable, divergent synthesis of bioactive meroterpenoids has been developed. A key component of this work is the invention of “borono-sclareolide”, a terpenyl radical precursor that enables gram-scale preparation of (+)-chromazonarol.
Darryl D. Dixon (2081077) +3 more
core +4 more sources
Meroterpenoids produced by fungi [PDF]
Natural Product Reports, 2009 This review deals with the isolation and structure elucidation of meroterpenoids (natural products of mixed biosynthetic origin which are partially derived from terpenoids) from higher and lower fungi, and discusses biosynthetic studies and biological activities as appropriate. It describes 333 fungal meroterpenoids and cites 195 references.
Regina, Geris, Thomas J, Simpson
openaire +2 more sources
Chemistry of fungal meroterpenoid cyclases
Natural Product Reports, 2021 Complex cyclization reactions of fungal meroterpenoid cyclases.
Lena Barra, Ikuro Abe
openaire +3 more sources
Merging Chemoenzymatic and Radical-Based Retrosynthetic Logic For Rapid and Modular Synthesis of Oxidized Meroterpenoids [PDF]
, 2019 We report a modular approach to access a range of oxidized meroterpenoids using a novel hybrid synthetic strategy involving enzymatic hydroxylation and radical based ...
Jian, Li +3 more
core +3 more sources
DataSheet1_Biological activities of meroterpenoids isolated from different sources.docx
, 2022 Meroterpenoids are natural products synthesized by unicellular organisms such as bacteria and multicellular organisms such as fungi, plants, and animals, including those of marine origin.
Kaushal H. Shah (13817812) +7 more
core +1 more source
Antioxidant Activity of Natural Hydroquinones
Antioxidants, 2022 Secondary metabolites derived from hydroquinone are quite rare in nature despite the original simplicity of its structure, especially when compared to other derivatives with which it shares biosynthetic pathways.
Rosa M. Giner +2 more
doaj +1 more source