Results 41 to 50 of about 2,271 (197)
Meroterpenoids with Immunosuppressive Activity from Edible Fungus Craterellus odoratus
Molecules, 2023 Two unusual polyketide–sesquiterpene metabolites, craterodoratins T (1) and U (2), along with the known compound craterellin A (3), were isolated from the higher fungus Craterellus odoratus.
Quan Dai +6 more
doaj +1 more source
Total Synthesis of Bioactive Marine Meroterpenoids: The Cases of Liphagal and Frondosin B
Marine Drugs, 2018 Liphagal and frondosin B are two marine-derived secondary metabolites sharing a very similar polyfused-benzofuran skeleton. The two tetracyclic meroterpenoids were isolated from marine sponges, both featuring a 6-5-7-6 fused ring system.
Yan Zong, Weijia Wang, Tao Xu
doaj +1 more source
Deciphering a Distinct Biosynthetic Pathway for Meroterpenoids in Bacteria [PDF]
Meroterpenoids are hybrid natural products that arise from the integration of terpenoid and non-terpenoid biosynthetic pathways. While the biosynthesis of fungal meroterpenoids typically follows a well-established sequence of prenylation, epoxidation ...
Lulu, Li +9 more
core +2 more sources
Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity
, 2015 Four new meroterpenoids, arnebinols A-D (1-4), and one new prenylated naphthoquinone, 5,8-O-dimethyl-11-deoxyalkannin (5), together with seven known meroterpenoids (6-12) were isolated from the roots of Arnebia euchroma.
Wang, Ming-Kui +6 more
core +1 more source
Acta Materia MedicaMeroterpenoids, a class of hybrid natural products derived from both terpenoid and non-terpenoid biosynthetic pathways, serve as a prolific source of drug leads, because of their structural complexity and extensive bioactivities.
Wenjie Luo +7 more
doaj +1 more source
Brasilianoids A–F, New Meroterpenoids From the Sponge-Associated Fungus Penicillium brasilianum
Frontiers in Chemistry, 2018 3,5-Dimethylorsellinic acid (DMOA) derived meroterpenoids comprise an unique class of natural products with diverse scaffolds and with a broad spectrum of bioactivities.
Jianping Zhang +5 more
doaj +1 more source
Actinomycetes as Producers of Biologically Active Terpenoids: Current Trends and Patents
Pharmaceuticals, 2023 Terpenes and their derivatives (terpenoids and meroterpenoids, in particular) constitute the largest class of natural compounds, which have valuable biological activities and are promising therapeutic agents.
Ekaterina V. Tarasova +3 more
doaj +1 more source
Molecules, 2015 Four new meroterpenoids, guignardones P–S (1–4), and three known analogues (5–7) were isolated from the endophytic fungal strain Guignardia mangiferae A348.
Zhang-Hua Sun +10 more
doaj +1 more source
Synthesis of a Model Compound of the Unique Meroterpenoids Cryptolaevilactones
Chemical and Pharmaceutical Bulletin, 2022 Cryptolaevilactones (CLs) A-L, found in the leaves and twigs of Cryptocarya laevigata, are unique natural meroterpenoids with a spiro[3.5]nonane skeleton. We report the total synthesis of a simplified model compound of CLs A-C. The synthetic route included introduction of a styryl group and coupling of a lactone moiety to a spiro ring system, which was
Miura, Yuta +2 more
openaire +2 more sources
Biokatalysatoren für die Geranylierung von Peptiden mit Linearen und Zyklischen Prenylgruppen
Angewandte Chemie, EarlyView.A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids ...
Sarolt Magyari +10 more
wiley +1 more source