Results 51 to 60 of about 2,951 (216)

Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the Genus Neosartorya †

Molecules, 2022
Fungi comprise the second most species-rich organism group after that of insects. Recent estimates hypothesized that the currently reported fungal species range from 3.5 to 5.1 million types worldwide. Fungi can grow in a wide range of habitats, from the
Joana D. M. de Sá, Decha Kumla, Tida Dethoup, Anake Kijjoa   +3 more
doaj   +1 more source

A MassQL‐Based Framework for Rule‐Guided MS/MS Class‐Level Retrieval and Analog Discovery of Cannabinoids

Rapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Cannabinoids comprise a chemically diverse group of meroterpenoids whose extensive isomerism, variable side‐chain length, and frequent oxidative or rearranged derivatives lead to strongly overlapping yet characteristic MS/MS fragmentation patterns. In untargeted LC–MS/MS datasets, this combination of structural diversity and spectral
Julia Maia Galvão de Queiroz, Fernanda Oliveira Chagas, Valdir Florêncio Veiga‐Júnior, Monica Costa Padilha, Ricardo M. Borges   +4 more
wiley   +1 more source

Recent Chemical Methodology Advances in the Total Synthesis of Meroterpenoids

Acta Chimica Slovenica, 2021
Heterogeneity of meroterpenoids arising from their dual biosynthetic origins is constantly provoking synthetic chemists to utilize their ingenuity and revise their retrosynthetic logic.
David Sarlah, Jan Petrovčič, Chad Nicholas Ungarean   +2 more
doaj   +1 more source

Marine-Derived Penicillium purpurogenum Reduces Tumor Size and Ameliorates Inflammation in an Erlich Mice Model

Marine Drugs, 2020
Background: This study addresses the antitumoral properties of Penicillium purpurogenum isolated from a polluted lagoon in Northeastern Brazil. Methods: Ethyl Acetate Extracellular Extract (EAE) was used.
Amanda Mara Teles, Leticia Prince Pereira Pontes, Sulayne Janayna Araújo Guimarães, Ana Luiza Butarelli, Gabriel Xavier Silva, Flavia Raquel Fernandes do Nascimento, Geusa Felipa de Barros Bezerra, Carla Junqueira Moragas-Tellis, Rui Miguel Gil da Costa, Marcos Antonio Custódio Neto da Silva, Fernando Almeida-Souza, Kátia da Silva Calabrese, Ana Paula Silva Azevedo-Santos, Maria do Desterro Soares Brandão Nascimento   +13 more
doaj   +1 more source

New Meroterpenoid Derivatives from the Pomegranate-Derived Endophytic Fungus Talaromyces purpureogenus

Molecules, 2023
In this study, we report the isolation of two new meroterpenoids, miniolutelide D (1) and miniolutelide E (13-epi-miniolutelide C) (2), along with two meroterpenoidal analogues (3 and 4) and two phenolic compounds (5 and 6) from the endophytic fungus ...
Alaa Anwar, Mohamed S. Elnaggar, Ahmed M. Elissawy, Nehal Ibrahim, Attila Mándi, Tibor Kurtán, Zhen Liu, Sherweit H. El-Ahmady, Rainer Kalscheuer   +8 more
doaj   +1 more source

Diastereoselective Formal Synthesis of Polycyclic Meroterpenoid (±)-Cochlearol A

The Journal of Organic Chemistry, 2021
A formal synthesis of (±)-cochlearol A was accomplished. The synthesis features Suzuki coupling and Friedel-Crafts cyclization as a convergent strategy to the functionalized tetralone ring and an intramolecular construction of the C/D ring involving sequential epoxide formation/acetal formation.
Telugu Venkatesh, Prathama S. Mainkar, Srivari Chandrasekhar   +2 more
openaire   +3 more sources

Phytochemical Composition and Potential Bioactivity With ADMET Analysis of Selected Species From Myrtaceae Family

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 1002-1029, July 2026.
Investigation of four medicinal plants of the family Myrtaceae. ABSTRACT Compounds derived from natural sources continue to serve as chemical scaffolds for designing prophylactic/therapeutic options for human healthcare. This study aimed to evaluate the phytochemical composition, antioxidant potential, in vitro anti‐inflammatory, antibacterial and ...
Archana Joshi, Vaishnavi Rawat, Ravendra Kumar, Stefania Garzoli, Anil Kumar Pant, Marcin Stocki, Valery A. Isidorov, Om Prakash, Dharmendra Singh Rawat   +8 more
wiley   +1 more source

Ganoderma lucidum-Derived Meroterpenoids Show Anti-Inflammatory Activity In Vitro

Molecules
Ganoderma lucidum, known as the “herb of spiritual potency”, is used for the treatment and prevention of various diseases, but the responsible constituents for its therapeutic effects are largely unknown.
Yun-Yun Liu, Dan Cai, Xin-Ping Tang, Yong-Xian Cheng   +3 more
doaj   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, Volume 4, Issue 3, Page 542-560, July 2026.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

Meroterpenoids from the Fungus Ganoderma sinensis and First Absolute Configuration Clarification of Zizhine H

Molecules, 2019
Five new meroterpenoids, zizhines P-S and U (1−4,7), together with two known meroterpenoids (5 and 6) were isolated from Ganoderma sinensis. Their structures including absolute configurations were assigned by using spectroscopic, computational, and
Yan-Jiao Yin, Dan-Ling Huang, Bin Qiu, Dan Cai, Jiao-Jiao Zhang, Shao-Xiang Wang, Da-Peng Qin, Yong-Xian Cheng   +7 more
doaj   +1 more source