Results 11 to 20 of about 10,865 (201)
Artificial Metalloenzymes for Enantioselective Catalysis Based on the Biotin-Avidin Technology
CHIMIA, 2008 Artificial metalloenzymes, based on the incorporation of a biotinylated catalytically active organometallic moiety within streptavidin, offer an attractive alternative to homogeneous, heterogeneous and enzymatic catalysis.
Jincheng Mao, Thomas R. Ward
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Computational Understanding of the Selectivities in Metalloenzymes
Frontiers in Chemistry, 2018 Metalloenzymes catalyze many different types of biological reactions with high efficiency and remarkable selectivity. The quantum chemical cluster approach and the combined quantum mechanics/molecular mechanics methods have proven very successful in the ...
Wen-Jie Wei +3 more
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Molecules, 2021 A series of benzenesulfonamides incorporating pyrazole- and pyridazinecarboxamides decorated with several bulky moieties has been obtained by original procedures.
Andrea Angeli +8 more
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Machine Learning Approaches for Metalloproteins
Molecules, 2022 Metalloproteins are a family of proteins characterized by metal ion binding, whereby the presence of these ions confers key catalytic and ligand-binding properties.
Yue Yu, Ruobing Wang, Ruijie D. Teo
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The NOX Family of Proteins Is Also Present in Bacteria
mBio, 2017 Transmembrane NADPH oxidase (NOX) enzymes have been so far only characterized in eukaryotes. In most of these organisms, they reduce molecular oxygen to superoxide and, depending on the presence of additional domains, are called NOX or dual oxidases ...
Christine Hajjar +7 more
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Evaluation of Metallo-β-Lactamase Susceptibility Testing in a Physiologic Medium
Microbiology Spectrum, 2021 Research in identifying alternative growth media that better mimic host conditions is gaining ground. Relative to nutrient-rich Mueller-Hinton broth (MHB), data on the influence of physiologic or host-mimicking media on metallo-β-lactamase (MBL ...
Tomefa E. Asempa +4 more
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Nitrogenase beyond the Resting State: A Structural Perspective
Molecules, 2023 Nitrogenases have the remarkable ability to catalyze the reduction of dinitrogen to ammonia under physiological conditions. How does this happen? The current view of the nitrogenase mechanism focuses on the role of hydrides, the binding of dinitrogen in ...
Rebeccah A. Warmack, Douglas C. Rees
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Molecules, 2018 We report the cloning and catalytic activity of a β-carbonic anhydrase (CA, EC 4.2.1.1), isolated from the pathogenic protozoan Entamoeba histolytica, EhiCA.
Susanna Haapanen +4 more
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Angewandte Chemie, EarlyView.Directional control within the secondary coordination sphere redefines CO2 reduction by iron porphyrins. Simply rearranging identical urea hydrogen‐bond donors modulates reactivity, revealing that optimal catalysis does not only arise from maximal intermediate stabilization, but also from directional, adaptive non‐covalent interactions that balance ...
Ashutosh Vishwakarma +7 more
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Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors
Metabolites, 2018 Carbonic anhydrases (CAs) are a superfamily of metalloenzymes widespread in all life, classified into seven genetically different families (α–θ).
Niccolò Chiaramonte +3 more
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