Results 181 to 190 of about 23,950 (217)
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Mevalonate synthesis in the mitochondria of yeast
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973Abstract 1. 1. Subcellular fractions were obtained bydifferential centrifugation of the homogenate of spheroplasts prepared from aerobically cultured Saccharomyces cerevisiae. The localization of the enzymes involved in the early stage of ergosterol synthesis was investigated. 2. 2.
I, Shimizu +3 more
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Multienzyme mevalonate pathway bioreactor
Biotechnology and Bioengineering, 2004AbstractThe five‐carbon metabolic intermediate isopentenyl diphosphate constitutes the basic building block for the biosynthesis of all isoprenoids in all forms of life. Two distinct pathways lead from amphibolic intermediates to isopentenyl diphosphate.
Autumn, Sutherlin, Victor W, Rodwell
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Mevalonate metabolism in pregnant rats
Metabolism, 1980Abstract Mevalonate is converted to cholesterol by the sterol pathway or can be oxidized to CO2 by the shunt pathway; the kidneys are the chief site of mevalonate metabolism in both pathways. Recently, a major sex difference in circulating mevalonate metabolism has been observed in rats and in humans; in rats, females oxidized mevalonate to CO2 at ...
K R, Feingold +3 more
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Mevalonate biosynthesis in rat liver
Lipids, 1970AbstractMevalonate synthesis in rat liver can occur not only from HMG‐CoA utilizing particle‐bound HMG‐CoA reductase, but from malonyl‐CoA utilizing soluble enzymes. From a strictly quantitative standpoint, synthesis from malonyl‐CoA appears to be of minor importance.
G M, Fimognari, V W, Rodwell
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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis
Cancer Cell, 2023Hao Nie, Rugang Zhang
exaly
Targeting the Mevalonate Pathway in Cancer
Trends in Cancer, 2021Dennis Juarez, David A Fruman
exaly