Results 231 to 240 of about 21,491 (246)

VCP/p97 cofactor UBXN1/SAKS1 regulates mitophagy by modulating MFN2 removal from mitochondria

Autophagy, 2022
Stephan Frank, Albert Neutzner
exaly  

Paeonol protects against doxorubicin-induced cardiotoxicity by promoting Mfn2-mediated mitochondrial fusion through activating the PKCε-Stat3 pathway

Journal of Advanced Research, 2023
Mingge Ding, Feng Fu
exaly  

Mfn2-mediated mitochondrial fusion promotes autophagy and suppresses ovarian cancer progression by reducing ROS through AMPK/mTOR/ERK signaling

Cellular and Molecular Life Sciences, 2022
Sanjay Kumar
exaly  

P67 MFN2 mutations cause compensatory mitochondrial DNA proliferation

Neuromuscular Disorders, 2012
K.S. Sitarz, P. Yu-Wai-Man, A. Pyle, J.D. Stewart, B. Rautenstrauss, P. Seeman, M.M. Reilly, R. Horvath, P.F. Chinnery   +8 more
openaire   +1 more source

The MFN2 gene is responsible for mitochondrial DNA instability and optic atrophy 'plus' phenotype

Brain, 2012
Arnaud Chevrollier, Vincent procaccio
exaly  

MFN2 provides antitumor efficacy in pancreatic cancer cells

Pancreatology, 2016
Qiang Sun, Weilin Wang
openaire   +1 more source

MFN2 Stabilization via Calpain-Resistant Gene Therapy in ALS

This concept paper was developed independently by a non-scientist with no formal training, based on personal research into ALS beginning in 2022. It explores a possible gene therapy approach for ALS that aims to protect a protein called MFN2, which helps keep mitochondria healthy and supports the connection between nerves and muscles.
openaire   +1 more source

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Journal of Cell Biology, 2003
Doris Chan, Andrew J Ewald, Scott E Fraser   +2 more
exaly  

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A

Science, 2018
Agostinho G Rocha, Antonietta Franco, Andrzej M Krezel   +2 more
exaly  

The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes

Molecular Cell, 2011
Suzanne Hoppins, Megan M Cleland, J Michael Mccaffery   +2 more
exaly