Strain-specific differences in cerulein-induced acute and recurrent acute murine pancreatitis [PDF]
Hyperstimulation with the secretagogue cerulein is a commonly used experimental model to study acute, recurrent acute and chronic pancreatitis in mice.
Alexandra Demcsák+3 more
doaj +2 more sources
Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity [PDF]
Background Recent discoveries suggest that arealization of the mammalian cortical sheet develops in a manner consonant with principles established for embryonic patterning of the body.
Wu Fangbai+4 more
doaj +4 more sources
Immune checkpoint inhibitors (ICI) have improved outcomes for a variety of malignancies; however, many patients fail to benefit. While tumor-intrinsic mechanisms are likely involved in therapy resistance, it is unclear to what extent host genetic ...
Justin B. Hackett+9 more
doaj +1 more source
Generation of live offspring from vitrified mouse oocytes of C57BL/6J strain. [PDF]
In mammals, unfertilized oocytes are one of the most available stages for cryopreservation because the cryopreserved oocytes can be used for assisted reproductive technologies, including in vitro fertilization (IVF) and intracytoplasmic sperm injection ...
Natsuki Kohaya+3 more
doaj +1 more source
Use of C57BL/6N mice on the variety of immunological researches
Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new inbred lines are being used in many research fields. C57BL/6 is
Hyun Keun Song, Dae Youn Hwang
doaj +1 more source
Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho+3 more
core +2 more sources
Corticotropin-releasing factor receptors couple to multiple g-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal excitability and associative learning [PDF]
Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the hippocampus.
Blank, T. (Thomas)+5 more
core +2 more sources
Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R+8 more
core +1 more source
Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]
Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO+2 more
core +1 more source
Placentophagia in Nonpregnant Nulliparous Mice: A Genetic Investigation [PDF]
The genetic influence on the response of nonpregnant nulliparous mice to foster placenta was investigated. Two highly inbred strains (BALB/cBy and C57BL/6By), their F1 hybrids, a backcross generation, and seven recombinant-inbred strains derived from the
Eleftheriou, Basil E.+1 more
core +1 more source