Strain-specific differences in cerulein-induced acute and recurrent acute murine pancreatitis [PDF]
Scientific ReportsHyperstimulation with the secretagogue cerulein is a commonly used experimental model to study acute, recurrent acute and chronic pancreatitis in mice.
Alexandra Demcsák +3 more
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Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity [PDF]
BMC Neuroscience, 2005 Background Recent discoveries suggest that arealization of the mammalian cortical sheet develops in a manner consonant with principles established for embryonic patterning of the body.
Wu Fangbai +4 more
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OncoImmunology, 2022 Immune checkpoint inhibitors (ICI) have improved outcomes for a variety of malignancies; however, many patients fail to benefit. While tumor-intrinsic mechanisms are likely involved in therapy resistance, it is unclear to what extent host genetic ...
Justin B. Hackett +9 more
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Generation of live offspring from vitrified mouse oocytes of C57BL/6J strain. [PDF]
PLoS ONE, 2013 In mammals, unfertilized oocytes are one of the most available stages for cryopreservation because the cryopreserved oocytes can be used for assisted reproductive technologies, including in vitro fertilization (IVF) and intracytoplasmic sperm injection ...
Natsuki Kohaya +3 more
doaj +1 more source
Predicting Yield Performance of Parents in Plant Breeding: A Neural Collaborative Filtering Approach [PDF]
PLoS ONE 15(5): e0233382 (2020), 2020 Experimental corn hybrids are created in plant breeding programs by crossing two parents, so-called inbred and tester, together. Identification of best parent combinations for crossing is challenging since the total number of possible cross combinations of parents is large and it is impractical to test all possible cross combinations due to limited ...
arxiv +1 more source
Use of C57BL/6N mice on the variety of immunological researches
Laboratory Animal Research, 2017 Inbred mice are an essential animal strain for research as they can improve the reproducibility and reliability of study results. The establishment of new inbred lines is continuing, and new inbred lines are being used in many research fields. C57BL/6 is
Hyun Keun Song, Dae Youn Hwang
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Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]
, 2017 Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho +3 more
core +2 more sources
Corticotropin-releasing factor receptors couple to multiple g-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal excitability and associative learning [PDF]
, 2003 Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the hippocampus.
Blank, T. (Thomas) +5 more
core +2 more sources
Responses to ethanol in C57BL/6 versus C57BL/6 × 129 hybrid mice [PDF]
, 2012 Although genetic background alters responses to ethanol, there has not yet been a methodical quantification of differences in ethanol-related behaviors between inbred and hybrid mice commonly used in gene-targeting studies. Here, we compared C57BL/6NTac ×
Janak, Patricia H +3 more
core +2 more sources
Experimentation with Animals: A Key Aspect of the 3Rs. The Genetic Quality [PDF]
, 2019 The genetic quality of laboratory animals is essential for reproducibility of scientific research. Working with animals of certifiedgenetic quality is still a pending issue in Argentina due to the lack of routine genetic controls, of information on the ...
Castillo, Nadia Sabiela +4 more
core +1 more source