Results 1 to 10 of about 350,782 (186)

Inter-individual Variability for High Fat Diet Consumption in Inbred C57BL/6 Mice [PDF]

Frontiers in Nutrition, 2019
Since inbred C57BL/6 mice are known to show inter-individual phenotypic variability for some traits, we tested the hypothesis that inbred C57BL/6 mice display a different tendency to consume a high fat (HF) diet.
P. N. De Francesco, M. Cornejo, Franco Barrile, G. García Romero, Spring Valdivia, M. F. Andreoli, M. Perelló   +6 more
semanticscholar   +6 more sources

Outbred CD1 mice are as suitable as inbred C57BL/6J mice in performing social tasks [PDF]

Neuroscience Letters, 2017
Inbred mouse strains have been used preferentially for behavioral testing over outbred counterparts, even though outbred mice reflect the genetic diversity in the human population better. Here, we compare the sociability of widely available outbred CD1 mice with the commonly used inbred C57BL/6J (C57) mice in the one-chamber social interaction test and
L. Hsieh, J. Wen, Laura Miyares, P. Lombroso, A. Bordey   +4 more
semanticscholar   +3 more sources

Discordant susceptibility of inbred C57BL/6 versus outbred CD1 mice to experimental fungal sepsis [PDF]

Cellular Microbiology, 2019
Individual susceptibility differences to fungal infection following invasive and/or immunosuppressive medical interventions are an important clinical issue.
E. Carreras, María Velasco de Andrés, Marc Orta-Mascaró, I. Simões, C. Català, Ó. Zaragoza, F. Lozano   +6 more
semanticscholar   +3 more sources

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice [PDF]

BMC Neuroscience, 2001
BackgroundThe presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice.
C. Specht, R. Schoepfer
semanticscholar   +5 more sources

Bone Brittleness Varies with Genetic Background in A/J and C57BL/6J Inbred Mice [PDF]

Journal of Bone and Mineral Research, 2001
Abstract The contribution of genetic and environmental factors to variations in bone quality are understood poorly. We tested whether bone brittleness varies with genetic background using the A/J and C57BL/6J inbred mouse strains.
K. Jepsen, D. Pennington, Ying-Lung Lee, M. Warman, Joseph H. Nadeau   +4 more
semanticscholar   +3 more sources

Discriminative stimulus effects of ethanol in C57BL/6J and DBA/2J inbred mice.

Alcoholism: Clinical and Experimental Research, 2002
Background: Two of the most widely used mouse strains for studying the behavioral effects of ethanol are C57BL/6J (B6) and DBA/2J (D2) mice. These strains exhibit marked differences in behavioral and physiological responses to ethanol. The subjective discriminative stimulus effects of ethanol may play a role in ethanol abuse, but the discriminative ...
K. Shelton, K. Grant
semanticscholar   +3 more sources

Experimental infection of inbred mice with herpes simplex virus. III. Comparison between newborn and adult C57BL/6 mice.

Journal of General Virology, 1982
We have previously shown that adult C57BL/6 mice are relatively resistant to intraperitoneal (i.p.) infection with herpes simplex virus type 1 (HSV-1). Here we show that newborn mice of the strain C57BL/6 are highly susceptible to i.p. infection with HSV-1. Newborn C57BL/6 mice, in contrast to adult mice, did not develop natural killer cell activity in
R. Zawatzky, H. Engler, H. Kirchner
semanticscholar   +3 more sources

Substrains matter in phenotyping of C57BL/6 mice

Experimental animals, 2021
The inbred mouse strain C57BL/6 has been widely used as a background strain for spontaneous and induced mutations. Developed in the 1930s, the C57BL/6 strain diverged into two major groups in the 1950s, namely, C57BL/6J and C57BL/6N, and more than 20 ...
K. Mekada, A. Yoshiki
semanticscholar   +1 more source

Chronobiology of alcohol: Studies in C57BL/6J and DBA/2J inbred mice [PDF]

Physiology & Behavior, 2013
Human alcoholics display dramatic disruptions of circadian rhythms that may contribute to the maintenance of excessive drinking, thus creating a vicious cycle. While clinical studies cannot establish direct causal mechanisms, recent animal experiments have revealed bidirectional interactions between circadian rhythms and ethanol intake, suggesting that
Alan M, Rosenwasser, Michael C, Fixaris
openaire   +2 more sources

Neuroimaging Evidence of Major Morpho-Anatomical and Functional Abnormalities in the BTBR T+TF/J Mouse Model of Autism [PDF]

, 2013
BTBR T+tf/J (BTBR) mice display prominent behavioural deficits analogous to the defining symptoms of autism, a feature that has prompted a widespread use of the model in preclinical autism research.
A Gozzi, A Gozzi, A Gozzi, A Gozzi, A Gozzi, AA Turk, AC Stanfield, AE Dorr, Alberto Galbusera, Alessandro Gozzi, Allan V. Kalueff, Angelo Bifone, AY Hardan, AY Hardan, B Avants, BA Babineau, BB Avants, BB Avants, BB Avants, BU Meye, D Badaruddin, D Wahlsten, D Wahlsten, E Anagnostou, F Tovar-Moll, G Zaharchuk, H Ito, H Utsunomiya, J Ashburner, J Ellegood, JL Silverman, JL Silverman, JL Silverman, JL Whitwell, JM Mountz, JP Lerch, JP Lerch, KL Hyde, L Ferrari, L Ferrari, LK Paul, LK Paul, Luca Dodero, M Magnuson, M Sasaki, M Wohr, M Yang, M Yang, M Yang, M Zilbovicius, MA Just, Maria Luisa Scattoni, Mario Damiano, ME Vissers, ML Scattoni, ML Senjem, MM Haznedar, MM Haznedar, MS George, N Boddaert, N Hadjikhani, O Devinsky, R Adolphs, R Via E, RG Gonzalez, RJ Zatorre, S Mori, S Schobel, S Shen, SM Smith, Sotirios A. Tsaftsaris, SR Das, SS Moy, SS Moy, T Ohnishi, T Ren, TW Frazier, VJ Bolivar, WS Brown   +78 more
core   +10 more sources