Results 31 to 40 of about 212,073 (210)
ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis. [PDF]
, 2016 Meta-analysis has become a popular tool for genetic association studies to combine different genetic studies. A key challenge in meta-analysis is heterogeneity, or the differences in effect sizes between studies.
Eskin, Eleazar +5 more
core +6 more sources
Frontiers in Behavioral Neuroscience, 2020 Sensation seeking is a heritable trait that is genetically correlated with substance use; the shared genetic mechanisms underlying these traits are largely unknown.
Price E. Dickson, Guy Mittleman
doaj +1 more source
Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart [PDF]
, 2017 The muscular ventricular septum separates the flow of oxygenated and de-oxygenated blood in air-breathing vertebrates. Defects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known about how they arise than rarer ...
Chen, Iuan-bor D +11 more
core +2 more sources
Sex differences in glucose metabolism of streptozotocin-induced diabetes inbred mice (C57BL/6J) [PDF]
Applied Biological Chemistry, 2020 AbstractConsidering that sex differences in glucose metabolism are observed in mice, researchers unconsciously use male mice to reduce variations by an estrogen cycle in female mice. In this study, we investigated the sex differences in glucose homeostasis in streptozotocin (STZ)-induced diabetes inbred mice (C57BL/6J).
Boyoung Kim +4 more
openaire +2 more sources
A phenotypic and molecular characterization of the fmr1-tm1Cgr Fragile X mouse [PDF]
, 2004 Fragile X Syndrome is the most common form of\ud inherited mental retardation. It is also known for having\ud a substantial behavioral morbidity, including autistic features. In humans, Fragile X Syndrome is almost always\ud caused by inactivation of the
Bauchwitz, Dr. Robert P.
core +1 more source
Laboratory Animal Research, 2018 Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam +5 more
doaj +1 more source
Laboratory Animal Research, 2020 To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and C4 mRNA, as well as C3 protein and C3 convertase activity in the serum and ...
Ji Won Park +5 more
doaj +1 more source
Consistent individual differences in some behaviors in mice of the C57Bl/6J inbred strain [PDF]
Anuario de Psicología, 2016 Mice of the inbred C57Bl/6J strain displayed considerable inter-mice variation in ambulation, rearing, grooming, and defecation in the open-field (coefficients of variation from 30% to 150%). Those differences were not random, because six measurements of the same behavior, taken along six months, were correlated (Kendall coefficients of concordance were ...
openaire +4 more sources
Memorias do Instituto Oswaldo Cruz, 1998 Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves +4 more
doaj +1 more source
Persistence of Leishmania antigen in C57Bl/6j inbred mice infected with Leishmania (Leishmania) amazonensis [PDF]
Revista da Associação Médica Brasileira, 1999 To develop an animal model for studying mucocutaneous leishmaniasis.The hind footpad of C57Bl/6j inbred mice was experimentally infected with 10(7) Leishmania (Leishmania) amazonensis promastigote and the skin was studied through light and electron transmission microscopy and immunohistochemistry (PAP) techniques.There were morphological evidences of ...
Vasconcellos, C. +2 more
openaire +5 more sources