Results 51 to 60 of about 329,438 (265)

Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

open access: yesLaboratory Animal Research, 2020
To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and C4 mRNA, as well as C3 protein and C3 convertase activity in the serum and ...
Ji Won Park   +5 more
doaj   +1 more source

Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair

open access: yesGenome Medicine, 2016
Nuclease-based technologies have been developed that enable targeting of specific DNA sequences directly in the zygote. These approaches provide an opportunity to modify the genomes of inbred mice, and allow the removal of strain-specific mutations that ...
J. Mianné   +12 more
semanticscholar   +1 more source

Consistent individual differences in some behaviors in mice of the C57Bl/6J inbred strain [PDF]

open access: yesAnuario de Psicología, 2016
Mice of the inbred C57Bl/6J strain displayed considerable inter-mice variation in ambulation, rearing, grooming, and defecation in the open-field (coefficients of variation from 30% to 150%). Those differences were not random, because six measurements of the same behavior, taken along six months, were correlated (Kendall coefficients of concordance were ...
openaire   +4 more sources

Persistence of Leishmania antigen in C57Bl/6j inbred mice infected with Leishmania (Leishmania) amazonensis [PDF]

open access: yesRevista da Associação Médica Brasileira, 1999
To develop an animal model for studying mucocutaneous leishmaniasis.The hind footpad of C57Bl/6j inbred mice was experimentally infected with 10(7) Leishmania (Leishmania) amazonensis promastigote and the skin was studied through light and electron transmission microscopy and immunohistochemistry (PAP) techniques.There were morphological evidences of ...
Vasconcellos, C.   +2 more
openaire   +5 more sources

QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains [PDF]

open access: yes, 2009
Peer reviewedPublisher ...
Blizard, David A   +6 more
core   +3 more sources

Helminth Parasites of Conventionally Maintained Laboratory Mice: II- Inbred Strains with an Adaptation of the Anal Swab Technique

open access: yesMemorias do Instituto Oswaldo Cruz, 1998
Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves   +4 more
doaj   +1 more source

Effects of Cdh23 single nucleotide substitutions on age-related hearing loss in C57BL/6 and 129S1/Sv mice and comparisons with congenic strains

open access: yesScientific Reports, 2017
A single nucleotide variant (SNV) of the cadherin 23 gene (Cdh23c.753A), common to many inbred mouse strains, accelerates age-related hearing loss (AHL) and can worsen auditory phenotypes of other mutations. We used homologous recombination in C57BL/6 NJ
K. Johnson   +5 more
semanticscholar   +1 more source

Missing Value Estimation using Clustering and Deep Learning within Multiple Imputation Framework [PDF]

open access: yesarXiv, 2022
Missing values in tabular data restrict the use and performance of machine learning, requiring the imputation of missing values. The most popular imputation algorithm is arguably multiple imputations using chains of equations (MICE), which estimates missing values from linear conditioning on observed values.
arxiv  

A Direct Comparison of Metabolic Responses to High-Fat Diet in C57BL/6J and C57BL/6NJ Mice

open access: yesDiabetes, 2016
Although nicotinamide nucleotide transhydrogenase (NNT)–deficient C57BL/6J (6J) mice are known to be highly susceptible to diet-induced metabolic disease, this notion stems primarily from comparisons of 6J mice to other inbred strains.
Kelsey H. Fisher-Wellman   +7 more
semanticscholar   +1 more source

Gender associated effects of the ethanolic extracts of Chinese propolis on the hepatic transcriptome in ethanol-treated mice [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2019
Objective(s): The current study investigated the potential hepatoprotective effects of the ethanolic extracts of Chinese propolis (EECP) on ethanol-induced fatty liver in mice.Materials and Methods: C57BL/6J mice were orally gavaged with 50% ethanol ...
Manhong Ye   +8 more
doaj   +1 more source

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