Results 61 to 70 of about 329,438 (265)

Immunological and nonimmunological control of severity of Trypanosoma musculi infections in C3H and C57BL/6 inbred mice [PDF]

Infection and Immunity, 1989
Studies concerned with the mechanisms responsible for relative resistance or susceptibility of strains of inbred mice to Trypanosoma musculi infections are presented. Treatment with 400 rads of ionizing radiation, silica dust, or trypan blue (reticuloendothelial blocking agents) rendered C3H mice unable to control the initial maximum level of parasite ...
Joseph F. Albright, Julia W. Albright
openaire   +2 more sources

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
A Ghazalpour, A Reverter, A Subramanian, AJ Butte, BA Taylor, BE Stranger, BH Voy, C Wu, Chris J. Cotsapas, CJ Cotsapas, D Gatti, D Vlieghe, David J. Nott, E Petretto, EJ Chesler, EJ Chesler, EJ Foss, Eva K. F. Chan, G Gibson, G Passador-Gurgel, HH Goring, I Hovatta, I Lönnstedt, J Brumm, JC Gower, Jeremy N. Pulvers, JJ Keurentjes, JJ Nadler, KA Frazer, L Bystrykh, M Bansal, M Mehrabian, M Wirth, MA West, Mark J. Cowley, MC Frith, Michael Y. Liu, MP Keller, MT Pletcher, MV Rockman, N Hubner, NN Batada, Oscar J. Luo, P Blache, Peter F. R. Little, R Ihaka, R Sandberg, RB Brem, RB Williams, RC Gentleman, RM Kuhn, Rohan B. H. Williams, S Biswas, TC Freeman, TM Fruchterman, V Emilsson, X Yang, Y Chen, Y Fukuoka   +58 more
core   +4 more sources

MICE: The International Muon Ionization Cooling Experiment [PDF]

AIPConf.Proc.821:427-431,2006, 2006
Ionization cooling of a muon beam is a key technique for a Neutrino Factory or Muon Collider. An international collaboration is mounting an experiment to demonstrate muon ionization cooling at the Rutherford Appleton Laboratory. We aim to complete the experiment by 2010.
arxiv   +1 more source

Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]

, 2004
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S., Simon, Michelle, Kumar, Saumya, Fernandes, Vitor E., Sylvius, Nicolas, Mallon, Ann-Marie, Denny, Paul, Andrew, Peter W.   +7 more
core   +5 more sources

Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population

Bone Reports, 2021
Mechanical unloading decreases bone volume and strength. In humans and mice, bone mineral density is highly heritable, and in mice the response to changes in loading varies with genetic background.
Michael A. Friedman, Abdullah Abood, Bhavya Senwar, Yue Zhang, Camilla Reina Maroni, Virginia L. Ferguson, Charles R. Farber, Henry J. Donahue   +7 more
doaj  

The MICE Muon Beam on ISIS and the beam-line instrumentation of the Muon Ionization Cooling Experiment [PDF]

, 2012
The international Muon Ionization Cooling Experiment (MICE), which is under construction at the Rutherford Appleton Laboratory (RAL), will demonstrate the principle of ionization cooling as a technique for the reduction of the phase-space volume occupied by a muon beam.
arxiv   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source

High-Resolution Maps of Mouse Reference Populations

G3: Genes, Genomes, Genetics, 2017
Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS ...
Petr Simecek, Jiri Forejt, Robert W. Williams, Toshihiko Shiroishi, Toyoyuki Takada, Lu Lu, Thomas E. Johnson, Beth Bennett, Christian F. Deschepper, Marie-Pier Scott-Boyer, Fernando Pardo-Manuel de Villena, Gary A. Churchill   +11 more
doaj   +1 more source

Postnatal Ontogeny of the Cranial Base and Craniofacial Skeleton in Male C57BL/6J Mice: A Reference Standard for Quantitative Analysis

Frontiers in Physiology, 2016
Growth of the craniofacial skeleton is a complex process controlled by both genetic and epigenetic factors, perturbations of which can lead to varying degrees of dysmorphology.
S. Vora, Esra D. Camci, T. Cox
semanticscholar   +1 more source

An excess of gene expression divergence on the X chromosome in Drosophila embryos; implications for the faster-X hypothesis [PDF]

PLoS Genetics (2012)8(12):e1003200, 2012
The X chromosome is present as a single copy in the heterogametic sex, and this hemizygosity is expected to drive unusual patterns of evolution on the X relative to the autosomes. For example, the hemizgosity of the X may lead to a lower chromosomal effective population size compared to the autosomes suggesting that the X might be more strongly ...
arxiv   +1 more source