Results 81 to 90 of about 329,438 (265)

Innate immune basis for rift valley fever susceptibility in mouse models [PDF]

, 2017
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre, Flamand, Marie, Godon, Ophélie, Jouvion, Grégory, Lathan, Rashida, Malissen, Marie, Panthier, Jean-Jacques, Simon-Chazottes, Dominique   +7 more
core   +2 more sources

Geometric morphometrics defines shape differences in the cortical area map of C57BL/6J and DBA/2J inbred mice

BMC Neuroscience, 2006
Background We previously described planar areal differences in adult mouse visual, somatosensory, and neocortex that collectively discriminated C57BL/6J and DBA/2J inbred strain identity.
Guan Monica, Wu Fangbai, Airey David C, Collins Christine E   +3 more
doaj   +1 more source

A Combined Adjuvant TF–Al Consisting of TFPR1 and Aluminum Hydroxide Augments Strong Humoral and Cellular Immune Responses in Both C57BL/6 and BALB/c Mice

Vaccines, 2021
TFPR1 is a novel adjuvant for protein and peptide antigens, which has been demonstrated in BALB/c mice in our previous studies; however, its adjuvanticity in mice with different genetic backgrounds remains unknown, and its adjuvanticity needs to be ...
Qiao Li, Zhihua Liu, Yi Liu, Chen Liang, Jiayi Shu, Xia Jin, Chuanyou Li, Zhihua Kou   +7 more
doaj   +1 more source

Structural, Spectroscopic, and Docking Analysis of N,O‐Donor Ligand Metal Complex Nanoparticles With Hypolipidemic Effects via Lipoprotein Lipase Activation in High‐Fat Diet Mice

Chemistry &Biodiversity, EarlyView.
Hypolipidemic influence of CETZ.2HCl‐(H1‐antihistamine) metal‐complexes on “C57Bl/6‐mice” fed high‐fat‐diet. ABSTRACT New Cd(II), Zn(II), and Cu(II) chelates with cetirizine.2HCl (CETZ.2HCl) in incidence of 1,10 phenanthroline monohydrate (Phen.H2O) were synthesized in search of new biologically active compounds.
Sherif M. Abd El‐Hamid, Safa W. Aziz, Amira A. Mohamed, Mohammed S. El‐Gedamy, Ahmed E. Salem, Soha F. Mohammed, Wael A. Zordok, Adriano Sofo, Mohamed A. Sabry, Sadeek A. Sadeek, Hazem S. Elshafie   +10 more
wiley   +1 more source

Forced Running Endurance Is Influenced by Gene(s) on Mouse Chromosome 10 [PDF]

, 2017
Acknowledgments The authors wish to acknowledge technical assistance from Mrs. Indrė Libnickienė and intellectual input from Dr. David A. Blizard. This research was funded by the European Social Fund under the Global Grant measure. Grant VP1-3.1-ŠMM-07-K-
Fokin, Andrej, Kvedaras, Mindaugas, Lionikas, Arimantas, Minderis, Petras, Ratkevicius, Aivaras, Venckunas, Tomas   +5 more
core   +1 more source

Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with Cdh23ahl

iScience, 2023
Summary: Mouse studies continue to help elaborate upon the genetic landscape of mammalian disease and the underlying molecular mechanisms. Here, we have investigated an Embigintm1b allele maintained on a standard C57BL/6N background and on a co-isogenic ...
Sherylanne Newton, Carlos Aguilar, Rosie K. Bunton-Stasyshyn, Marisa Flook, Michelle Stewart, Walter Marcotti, Steve Brown, Michael R. Bowl   +7 more
doaj  

mGluR5 Knockout mice exhibit normal conditioned place-preference to cocaine [PDF]

, 2012
Metabotropic glutamate receptor 5 (mGluR5) null mutant (-/-) mice have been reported to totally lack the rein- forcing or locomotor stimulating effects of cocaine. We tested mGluR5 -/- and +/+ mice for their locomotor and conditioned place- preference response to cocaine.
arxiv   +1 more source

What’s in a (Sub)strain?

Stem Cell Reports, 2018
C57BL/6J and C57BL/6N inbred mice are widely, and often interchangeably, used for stem cell research; yet, these substrains harbor discrete genetic differences that can cause phenotypic disparities.
Jill M. Goldstein, Amy J. Wagers
doaj  

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

Reproductive Biology and Endocrinology, 2007
Background A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The miglustat-
Boomkamp Stephanie, Gottwald Ulrich, Leifke Eckhard, Fritsch Martin, Voigtmann Ulrike, Walden Charlotte M, Bone Wilhelm, Platt Frances M, van der Spoel Aarnoud C   +8 more
doaj   +1 more source

The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape. [PDF]

, 2017
Inbred genetic background significantly influences the expression of phenotypes associated with known genetic perturbations and can underlie variation in disease severity between individuals with the same mutation.
Hallgrímsson, Benedikt, Klein, Ophir, Marangoni, Pauline, Percival, Christopher J, Tapaltsyan, Vagan   +4 more
core   +1 more source