Quantifying Radiosensitization of PSMA-Targeted Gold Nanoparticles on Prostate Cancer Cells at Megavoltage Radiation Energies by Monte Carlo Simulation and Local Effect Model [PDF]
Pharmaceutics, 2022 Active targeting gold nanoparticles (AuNPs) are a very promising avenue for cancer treatment with many publications on AuNP mediated radiosensitization at kilovoltage (kV) photon energies.
Ryder M. Schmidt +8 more
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The complexity of DNA damage by radiation follows a Gamma distribution: insights from the Microdosimetric Gamma Model [PDF]
Frontiers in Oncology, 2023 IntroductionDNA damage is the main predictor of response to radiation therapy for cancer. Its Q8 quantification and characterization are paramount for treatment optimization, particularly in advanced modalities such as proton and alpha-targeted therapy ...
Alejandro Bertolet +3 more
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Calculation of alpha particle single-event spectra using a neural network [PDF]
Frontiers in OncologyIntroductionA neural network was trained to accurately predict the entire single-event specific energy spectra for use in alpha-particle microdosimetry calculations.MethodsThe network consisted of 4 inputs and 21 outputs and was trained on data ...
Layth Alkhani +3 more
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Impact of Radiation Quality on Microdosimetry and Chromosome Aberrations for High-Energy (>250 MeV/n) Ions [PDF]
Life, 2022 Studying energy deposition by space radiation at the cellular scale provides insights on health risks to astronauts. Using the Monte Carlo track structure code RITRACKS, and the chromosome aberrations code RITCARD, we performed a modeling study of single-
Floriane Poignant +3 more
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Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors [PDF]
Scientific Reports, 2022 The present work reports on the microdosimetry measurements performed with the two first multi-arrays of microdosimeters with the highest radiation sensitive surface covered so far.
Diana Bachiller-Perea +6 more
doaj +2 more sources
Note on uncertainty in Monte Carlo dose calculations and its relation to microdosimetry [PDF]
Zeitschrift für Medizinische PhysikPurpose: The Type A standard uncertainty in Monte Carlo (MC) dose calculations is usually determined using the “history by history” method. Its applicability is based on the assumption that the central limit theorem (CLT) can be applied such that the ...
Günther H. Hartmann, Hans G. Menzel
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Microdosimetry for hadron therapy: A state of the art of detection technology
Frontiers in Physics, 2022 The interest in hadron therapy is growing fast thanks to the latest technological advances in accelerators and delivery technologies, to the development of more and more efficient and comprehensive treatment planning tools, and due to its increasing ...
Gabriele Parisi +4 more
doaj +1 more source
Frontiers in Physics, 2022 The present work shows the performance of two new large microdosimetry multi-array systems having two different configurations, namely, pixel and strip configurations.
Diana Bachiller-Perea +8 more
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Frontiers in Physics, 2023 One of the most intriguing and still pending questions in radiobiology is to understand whether and how natural environmental background radiation has shaped Life over millions of years of evolution on Earth.
Patrizia Morciano +42 more
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Progress in 3D Silicon Radiation Detectors
Frontiers in Physics, 2022 In the past few years, there has been an increasing interest toward 3D silicon radiation detectors. Owing to their unique architecture, 3D detectors provide a remarkable radiation hardness at relatively low bias voltage (hence low power dissipation ...
Gian-Franco Dalla Betta +2 more
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