Results 111 to 120 of about 16,085 (225)

D‐Allulose as a Low‐Calorie Sweetener: A 30‐Day Randomized, Double‐Blind Study on Gastrointestinal Tolerance and Systemic Safety to Support Its Application in Healthy Diets

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This graphical abstract presents the key design and findings of a 30‐day trial evaluating the safety of fermented D‐allulose in healthy Chinese adults. Fifty eligible adults were randomized to receive either low‐dose (24 g/day, n = 24) or high‐dose (36 g/day, n = 26) D‐allulose for 30 days.
Lijuan Qi, Junyu Ning, Jiangli Han, Nan Zhang, Wenjing Zhang, Fangfang Wang, Dan Li, Zinan Li, Yanmin Nie, Haiming Jing, Shan Gao   +10 more
wiley   +1 more source

Curcumin Attenuates Aroclor 1254‐Induced Oxidative, Genotoxic, and Apoptotic Alterations in HepG2 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
In HepG2 cells, Aroclor 1254 induced oxidative stress, DNA damage, apoptosis, and mutagenicity; co‐treatment with curcumin restored antioxidant defenses (GSH/thiols; SOD, CAT, GPx, GR, TrxR), reduced ROS and comet/8‐OHdG readouts, and attenuated caspase activation, demonstrating curcumin's hepatoprotective and genoprotective modulation of PCB toxicity.
Pınar Erkekoğlu, Selinay Başak Erdemli Köse, Hülya Tezel Yalçın, Deniz Arca Çakır   +3 more
wiley   +1 more source

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

Protein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source

From Gene Copies to Cell Numbers: Advancing Quantitative Approaches in Protistan Ecology Using Digital PCR

Molecular Ecology Resources, Volume 26, Issue 5, July 2026.
ABSTRACT Quantifying abundances of unicellular eukaryotes (protists) remains a central challenge in microbial ecology, as methodological differences can strongly influence abundance estimates and ecological interpretation. Although molecular tools have thus far greatly improved our understanding of protists, high rRNA gene copy numbers limit ...
Megan Gross, Ulrike Koll, Bettina Sonntag, Thorsten Stoeck   +3 more
wiley   +1 more source

The muntjac spindle staining assay: An investigation of the ability of this assay to detect potential aneuploidy inducing agents

, 1988
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.An assay using muntjac fibroblasts in conjunction with a differential spindle and chromosome stain was developed and evaluated for its ability to detect ...
Pascoe, Sally Ann
core  

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, Volume 58, Issue 4, Page 970-980, July 2026.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, Volume 178, Issue 3, Page 417-427, July 2026.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Flavouring Group Evaluation 216 Revision 3 (FGE.216Rev3): Consideration of the genotoxic potential of α,β‐unsaturated 2‐phenyl‐2‐alkenals from subgroup 3.3 of FGE.19

EFSA Journal, Volume 24, Issue 7, July 2026.
Abstract The EFSA Panel on Food Additives and Flavourings (FAF) evaluated the genotoxic potential of two flavouring substances, 2‐phenylcrotonaldehyde [FL‐no: 05.062] and 5‐methyl‐2‐phenylhex‐2‐enal [FL‐no: 05.099] from subgroup 3.3 of FGE.19, in the Flavouring Group Evaluation 216 revision 3 (FGE.216Rev3).
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, María José Frutos Fernández, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Claudia Bolognesi, Eugenia Cordelli, Gisela Degen, Karl‐Heinz Engel, Maria Carfí, Alessandra Tosato, Carla Martino   +23 more
wiley   +1 more source

What are the Criteria and Conditions for Performing the Micronucleus Assay in Oral Exfoliated Cells from Waterpipe and Cigarette Smokers? [PDF]

Int J Prev Med, 2023
Ribeiro DA.
europepmc   +1 more source

Report on the buccal micronucleus assay workshop organized by the International Human Micronucleus (HUMN) project - Antalya, Turkey 2007

, 2009
This report describes the aims, discussion and outcomes of the first Human Micronucleus collaborative project workshop on the buccal micronucleus assay. It was agreed at the workshop that three activities should be initiated as soon as possible namely (i)
Holland, Nina, Burgaz, Sema, Bonassi, S., Knasmueller, S., Fenech, M., Knasmueller, Siegfried, Fenech, Michael, Holland, N., Bonassi, Stefano, Burgaz, S.   +9 more
core   +1 more source