Results 91 to 100 of about 16,085 (225)

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

Environmental Toxicology, EarlyView.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves, Matheus Mantuanelli Roberto, Adriana Fabiana Corrêa da Silva, Maria Aparecida Marin‐Morales   +3 more
wiley   +1 more source

Evaluation of genotoxic effect of different smoking habits by detecting micronucleus frequency in university students, A case control study

Zanco Journal of Medical Sciences
Background and objective: Cigarettes, shisha, and e-cigarettes are significant etiologic factors of oral cancers. Buccal mucosa is the first tissue that faces the pollutants and might reflect unhealthy processes in the body.
Reshna Kamal Albarzanji
doaj   +1 more source

Antioxidant and Cytoprotective Effect of Piper aduncum L. against Sodium Fluoride (NaF)-Induced Toxicity in Albino Mice

Toxics, 2019
Piper aduncum, commonly known as matico, is a plant that grows in the mountainous and coastal regions of Peru, and is studied for its antimicrobial properties and various ethnopharmacological uses.
Oscar Herrera-Calderon, Luz Chacaltana-Ramos, Ricardo Ángel Yuli-Posadas, Bertha Pari-Olarte, Edwin Enciso-Roca, Johnny Aldo Tinco-Jayo, Juan Pedro Rojas-Armas, Luis Miguel Visitación Felix-Veliz, Cesar Franco-Quino   +8 more
doaj   +1 more source

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, EarlyView.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

Application of the in vitro rat hepatocyte micronucleus assay in genetic toxicology testing

, 1997
The investigation of micronuclei in mitogenic stimulated hepatocytes in vitro is a quite new area of research. Nevertheless, a relatively large database comprising more than 40 tested compounds of various classes has been generated up to now.
Müller-Tegethoff, Kerstin, Kasper, Peter, Kersten, Birgit, Müller, Lutz   +3 more
core   +1 more source

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

A Unified Deep Learning Framework for Instance Segmentation Across Diverse Cytological Stains

Cytopathology, EarlyView.
Transformer‐based unified cytology segmentation across Papanicolaou, Feulgen and AgNOR achieves stain‐invariant performance. Mask2Former maximises boundary precision (AP75) on the combined dataset, enabling one model to replace multiple stain‐specific deployments without accuracy loss while simplifying clinical integration.
Luís Otávio Santos, Rodrigo de Paula E. Silva Ribeiro, Bibiana Quatrin Tiellet, Laura Maria Effting Silva, Fabiana Botelho de Miranda Onofre, Alexandre Sherlley Casimiro Onofre, Aldo von Wangenheim   +6 more
wiley   +1 more source

An investigation of the genotoxic potential of a well-characterized yerba mate extract

Toxicology Reports
Yerba Mate (Ilex paraguariensis) is historically used as a beverage and its extracts are considered traditional medicine in South America. Extract use has been expanding to North American and European markets and the currently available genetic ...
C. Doepker, C. Rabert, P. Heard, T. Dubnicka, N. Choksi, A. Eapen   +5 more
doaj   +1 more source

Increased Genetic Instability in Exfoliated Oral Cells in Patients With Epidermolysis Bullosa

Oral Diseases, EarlyView.
ABSTRACT Objective To analyze the nuclear abnormalities of cytotoxicity—karyorrhexis (KR), karyolysis (KL), and pyknosis (PN)—and genotoxicity—micronucleus (MN) in exfoliated cells from different sites of the oral mucosa in patients with Epidermolysis Bullosa (EB) and a control group.
Ana Carolina Sias Franco Franzosi, Rebeca Ferreira Badaró, Lucas Fernandes Leal, Rosalie Matuk Fuentes Torrelio, Willian Grassi Bautz, Leticia Nogueira da Gama‐de‐Souza   +5 more
wiley   +1 more source