Results 91 to 100 of about 870,242 (177)

Antioxidant and Cytoprotective Effect of Piper aduncum L. against Sodium Fluoride (NaF)-Induced Toxicity in Albino Mice

Toxics, 2019
Piper aduncum, commonly known as matico, is a plant that grows in the mountainous and coastal regions of Peru, and is studied for its antimicrobial properties and various ethnopharmacological uses.
Oscar Herrera-Calderon, Luz Chacaltana-Ramos, Ricardo Ángel Yuli-Posadas, Bertha Pari-Olarte, Edwin Enciso-Roca, Johnny Aldo Tinco-Jayo, Juan Pedro Rojas-Armas, Luis Miguel Visitación Felix-Veliz, Cesar Franco-Quino   +8 more
doaj   +1 more source

PEGylated Chrysin: In Vitro Biological Activity and Mechanistic Insights in HepG2 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
PEGylated chrysin exhibited antiproliferative effects in HepG2 cells, inducing apoptosis, membrane damage, genotoxicity, and wound closure. Compared to paclitaxel, it caused lower ROS production and overall cytotoxicity, while efficiently accumulating in the cytoplasm, supporting its potential as a liver cancer therapeutic candidate. ABSTRACT PEGylated
Fátima Belén Gasser, Julia Oggero, María Sol Renna, María Florencia Beltramino, Candela Simonetto, Lucía Dominguez, Hugo Héctor Ortega, Santiago Eduardo Vaillard, Victoria Anahí Vaillard, María Eugenia Baravalle   +9 more
wiley   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

Report on the buccal micronucleus assay workshop organized by the International Human Micronucleus (HUMN) project-025EFAntalya, Turkey 2007

, 2009
This report describes the aims, discussion and outcomes of the first Human Micronucleus collaborative project workshop on the buccal micronucleus assay. It was agreed at the workshop that three activities should be initiated as soon as possible namely (i)
Holland, Nina, Burgaz, Sema, Knasmueller, Siegfried, Fenech, Michael, Bonassi, Stefano   +4 more
core   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

ChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

An investigation of the genotoxic potential of a well-characterized yerba mate extract

Toxicology Reports
Yerba Mate (Ilex paraguariensis) is historically used as a beverage and its extracts are considered traditional medicine in South America. Extract use has been expanding to North American and European markets and the currently available genetic ...
C. Doepker, C. Rabert, P. Heard, T. Dubnicka, N. Choksi, A. Eapen   +5 more
doaj   +1 more source

Mitigating Photoinduced Reactive Oxygen Species From TiO2 and ZnO UV Filters: Materials Design and Evaluation

ChemistrySelect, Volume 11, Issue 42, 10 November 2026.
Photoinduced reactive oxygen species (ROS) from titanium dioxide (TiO2) and zinc oxide (ZnO) ultraviolet (UV) filters can be controlled through particle engineering, surface passivation, and formulation design. This Review links material structure and interfacial chemistry with ROS evaluation and proposes a tiered framework from photoreactivity ...
Chenge Wang
wiley   +1 more source

7_Supplementary_Figures - Baseline effects of non-flavored e-liquids in the in vitro micronucleus assay

, 2019
7_Supplementary_Figures for Baseline effects of non-flavored e-liquids in the in vitro micronucleus assay by Daniel J Smart, Fabian R Helbling, Damian McHugh and Patrick Vanscheeuwijck in Toxicology Research and ...
Fabian R Helbling (8065466), Daniel J Smart (8065463), Damian McHugh (8065469), Patrick Vanscheeuwijck (677021)   +3 more
core   +1 more source

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, Volume 41, Issue 11, Page 1125-1138, November 2026.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source

Integrated Biomarker Assessment of Bifenthrin, Chlorpyrifos and Endosulfan Toxicity in Indigenous Carps (Catla catla and Labeo rohita): Oxidative Stress, Genotoxicity and Nuclear Alterations

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Combined exposure to bifenthrin–chlorpyrifos and bifenthrin–endosulfan mixtures induced oxidative stress, genotoxicity and nuclear abnormalities in Catla catla and Labeo rohita. Antioxidant and DNA damage biomarkers provide sensitive tools for assessing pesticide‐related ecological risks in aquatic environments. ABSTRACT Background The extensive use of
Huma Naz, Sajid Abdullah, Tanveer Ahmed, Khalid Abbas, Muhammad Umar Ijaz, Qudrat Ullah, Shabana Naz, Rifat Ullah Khan, Luciana Rossi, Sohail Ahmad, Rasha Alonaizan   +10 more
wiley   +1 more source