Results 21 to 30 of about 870,242 (177)

Performance of HepaRG and HepG2 Cells in the High-Throughput Micronucleus Assay for in Vitro Genotoxicity Assessment [PDF]

Journal of Toxicology and Environmental Health - Part A: Current Issues, 2020
Xiaoqing Guo, Dayton M Petibone, Nan Mei
exaly   +2 more sources

New direct contact approach to evaluate soil genotoxicity using the Vicia faba micronucleus test. [PDF]

, 2009
A method to assess micronucleus (MN) induction in Vicia faba roots by direct contact exposure to a solid matrix was developed. The procedure comprised a 5-d germination period, as in the well-known method using aqueous extracts.
Cecchi, M., Marcato, Claire-Emmanuelle, Cotelle, Sylvie, Pinelli, Eric, Cecchi, Marie, Guiresse, Agnès Maritchù, Guiresse, Maritxu, Claire-Emmanuelle Marcato-Romain, Sylvie Cotelle, Eric Pinelli, Maritxu Guiresse, Marie Cecchi   +11 more
core   +1 more source

Comparative Evaluation of Genotoxicity of Captan in Amphibian Larvae (Xenopus laevis and Pleurodeles waltl) Using the Comet Assay and the Micronucleus Test [PDF]

, 2006
Captan (N-trichloromethylthio-4-cyclohexene-1,2-dicarboximide) is a fungicide used to inhibit the growth of many types of fungi on plants used as foodstuffs.
Gauthier, Laury, Devaux, Alain, Gauthier, L., Mouchet, F., Ferrier, V., Mouchet, Florence, Ferrier, Vincent, Mailhes, Corinne, Devaux, A.   +8 more
core   +1 more source

In vitro evaluation of mutagenic, cytotoxic, genotoxic and oral irritation potential of nicotine pouch products

Toxicology Reports, 2022
Non-clinical in vitro studies were conducted to investigate the characteristics of extracts from tobacco free nicotine pouches alongside a reference snus product and/or 1R6F reference cigarette.
Jacqueline Miller-Holt, Irene Baskerville-Abraham, Masanori Sakimura, Toshiro Fukushima, Andrea Puglisi, Jeremie Gafner   +5 more
doaj   +1 more source

Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (MutatoxR and Ames tests) [PDF]

, 2006
The management of contaminated soils and wastes is a matter of considerable human concern. The present study evaluates the genotoxic potential of aqueous extracts of two soils (leachates) and of bottom ash resulting from municipal solid waste ...
Gauthier, Laury, Devaux, Alain, Gauthier, L., Triffault, Gaëlle, Mouchet, F., Ferrier, V., Mouchet, Florence, Jourdain, M.J., Jourdain, Marie-José, Ferrier, Vincent, Triffault, G., Mailhes, Corinne   +11 more
core   +1 more source

Micronucleus Assay in Urothelial Cells in Cancer Cervix [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Cancer ranks third among the ten leading global causes of death. To evaluate the genotoxic risks, observed as DNA damages, can be assessed by Micronucleus (MN) test.
Suresh Kumar Sundararajan, Pratheepa Sivasankari Natarajan, Kanchana   +2 more
doaj   +1 more source

Assessment of the genotoxicity of olive mill waste water (OMWW) with the Vicia faba micronucleus test [PDF]

, 2007
The present study concerns the genotoxicity of olive mill waste water (OMWW) generated in mills producing olive oil in Morocco. The Vicia faba micronucleus test was used to evaluate the genotoxicity of OMWW and the six major phenolic compounds identified
Hafidi, Mohamed, Revel, J.C., Pinelli, Eric, Merlina, Georges, El Hajjouji, Houda, Guiresse, Agnès Maritchù, Revel, Jean-Claude, Guiresse, Maritxu   +7 more
core   +1 more source

Buccal Micronucleus Cytome Assay in Sickle Cell Disease [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Sickle Cell Anaemia (SCA) is a commonly inherited blood disorder preceded by episodes of pain, chronic haemolytic anaemia and severe infections.
Mallika Bokka Sri Satya Naga, Shreya Gour, Nalini Nallagutta, Kranti Kiran Reddy Ealla, Surekha Velidandla, Sangameshwar Manikya   +5 more
doaj   +1 more source

Mutagenic impact on fish of runoff events in agricultural areas in south-west France [PDF]

, 2011
When heavy rainfall follows herbicide application, the intense surface runoff causes stream water contamination. Aquatic organisms are then briefly exposed to a complex mixture of contaminants.
Pinelli, Eric, S. Jean, Merlina, Georges, T. Polard, Sánchez-Pérez, J.M., L. Gauthier, Sanchez-Pérez, José Miguel, Gauthier, Laury, Polard, Thierry, Jean, Séverine, G. Merlina, E. Pinelli, J.M. Sánchez-Pérez, C. Laplanche, Laplanche, Christophe   +14 more
core   +1 more source

Evaluation of genotoxicity using the micronucleus assay and nuclear abnormalities in the tropical sea fish Bathygobius soporator (Valenciennes, 1837) (Teleostei, Gobiidae)

Genetics and Molecular Biology, 2009
The micronucleus and nuclear abnormalities assays have been used increasingly to evaluate genotoxicity of many compounds in polluted aquatic ecossystems.
Toni P. Galindo, Lília M. Moreira
doaj   +1 more source