Results 61 to 70 of about 870,242 (177)

HepaRG hep+ and biological tracers for a new in vitro micronucleus assay

, 2017
HepaRG hep+ and biological tracers for a new in vitro micronucleus assay.
Mirey, Gladys
core   +2 more sources

Clastogenicity of Piper cubeba (Piperaceae) seed extract in an in vivo mammalian cell system

Genetics and Molecular Biology, 2007
The plant Piper cubeba is widely distributed in tropical and subtropical regions and is used medically for various purposes but has not yet been evaluated for genotoxicity.
Adriana Pereira Freire Junqueira, Fabio Ferreira Perazzo, Gustavo Henrique Bianco Souza, Edson Luis Maistro   +3 more
doaj   +1 more source

Dietary Flavonoid Hyperoside Ameliorates High‐Fat Diet‐Induced Type 2 Diabetes Mellitus by Enhancing Brown Adipose Tissue Thermogenesis, White Adipose Tissue Browning, and Gut Microbiota Remodeling

Phytotherapy Research, EarlyView.
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai, WenXin Zeng, Yu Luo, Qiang Liu, CuiPing Jiang, YanKui Yi, JieYu Chen, ChunYan Shen   +7 more
wiley   +1 more source

Cytogenotoxic Effects of Fluopyram in Allium cepa Root Cells Involving Microtubule Disruption

Environmental Toxicology, EarlyView.
ABSTRACT Fluopyram is a next‐generation fungicide widely used in agriculture; however, its persistence in soils and mobility toward aquatic systems have raised concerns regarding potential ecotoxicological risks. This study evaluated the cytogenotoxic effects of a commercial fluopyram‐based pesticide formulation on Allium cepa root meristem cells ...
Carlos Filipe Camilo‐Cotrim, Natanael Alves da Silva, Gabriela Gomes Lima, Igor Rodrigues Vasconcelos, Luciana Souza Ondei, Elisa Flávia Luiz Cardoso Bailão, Antônio Sérgio Nakao de Aguiar, Marcelino Benvindo‐Souza, Leonardo Luiz Borges, Virgínia Damin, Luciane Madureira Almeida   +10 more
wiley   +1 more source

Assessment of the genetic risks of a metallic alloy used in medical implants

Genetics and Molecular Biology, 2011
The use of artificial implants provides a palliative or permanent solution for individuals who have lost some bodily function through disease, an accident or natural wear. This functional loss can be compensated for by the use of medical devices produced
Cristiano C. Gomes, Leonardo M. Moreira, Vanessa J.S.V. Santos, Alfeu S. Ramos, Juliana P. Lyon, Cristina P. Soares, Fabio V. Santos   +6 more
doaj  

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

Environmental Toxicology, EarlyView.
ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur, Rahsan Ilikci‐Sagkan, Recep Liman   +2 more
wiley   +1 more source

Trace Levels of Triclosan May Affect Root Growth and Morphology in Cultivated Plants

Environmental Toxicology, EarlyView.
ABSTRACT Triclosan (TCS) is a micropollutant frequently detected in biosolids applied to agricultural soils. In soil solution—where it is potentially bioavailable to roots—it occurs at residual concentrations (ng L−1). Nevertheless, the ecotoxicological implications of TCS exposure in agricultural crops at these concentrations are still not fully ...
Lizandra de Souza Ratuchinski, Edson Araujo de Almeida, Matheus Cristiano Hermann Massariol, Diego Espirito Santo, Carmem Lúcia Henrich, Bianca da Cruz, Danielle Cristina da Silva de Oliveira, Gideã Taques Tractz, Regiane da Silva Gonzalez, Osvaldo Valarini Junior, Ana Paula Peron   +10 more
wiley   +1 more source

Automated urine analysis of atypical urothelial cells for urothelial carcinoma: a prospective study

BJU International, EarlyView.
Objectives To prospectively evaluate the diagnostic value of atypical urothelial cells (Atyp.C), an automatically determined quantitative parameter of the Sysmex UF‐5000 urine particle analyser (Sysmex Corp., Kobe, Japan), as a non‐invasive biomarker for urothelial carcinoma (UC). Early diagnosis of UC remains challenging despite advances in diagnostic
Maximilian Reimann, Thorsten Schlomm, Nathalie Winkler, Jeutner Jonathan, Jodie Maksoud, Ardita Aleti, Kai Kappert, Katharina Friedrich, Amir Jahic   +8 more
wiley   +1 more source

Protective effects of acerola juice on genotoxicity induced by iron in vivo

Genetics and Molecular Biology, 2016
Metal ions such as iron can induce DNA damage by inducing reactive oxygen species (ROS) and oxidative stress. Vitamin C is one of the most widely consumed antioxidants worldwide, present in many fruits and vegetables, especially inMalpighia glabra L ...
Roberta Nunes Horta, Vivian Francilia Silva Kahl, Merielen da Silva Sarmento, Marisa Fernanda Silva Nunes, Carem Rejane Maglione Porto, Vanessa Moraes de Andrade, Alexandre de Barros Falcão Ferraz, Juliana Da Silva   +7 more
doaj   +1 more source

Teriparatide Topical Delivery Supports Osseointegration in Ovariectomized Rats Receiving Cafeteria Diet and Bisphosphonate: An In Vivo Experimental Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Background Postmenopausal osteoporosis associated with cafeteria diet and bisphosphonate therapy may impair peri‐implant bone repair. Therefore, strategies to enhance osseointegration are needed. Aim This study investigated whether teriparatide‐coated implant surfaces enhance osseointegration in a rodent model of estrogen deficiency (OVX) and ...
Ana Cláudia Ervolino da Silva, Fábio Roberto de Souza Batista, Jaqueline Suemi Hassumi, Naara Gabriela Monteiro, Marina Santos Fernandes, Luana Marotta Reis Vasconcellos, Gabriel Mulinari‐Santos, Reinhard Gruber, Paulo Noronha Lisboa‐Filho, Roberta Okamoto   +9 more
wiley   +1 more source