Chronic ethanol consumption in mice does not induce DNA damage in somatic or germ cells, evaluated by the bone marrow micronucleous assay and the dominant lethal mutation assay [PDF]
, 2012 Indexación: Web of Science; ScieloAlthough alcohol is known to be a carcinogen for humans, ethanol-genotoxicity studies are incomplete. Ethanol seems not to be a bacterial mutagen, but the results are conflicting in rodent assays.
Ellahueñe, Manuel +2 more
core +1 more source
In Vitro Mutagenic and Genotoxic Assessment of a Mixture of the Cyanotoxins Microcystin-LR and Cylindrospermopsin [PDF]
, 2019 The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different than those observed for single cyanotoxins, as interaction phenomena cannot be discarded. Moreover, mixtures are a more probable exposure scenario. However,
Cameán Fernández, Ana María +4 more
core +1 more source
Mutagenic impact on fish of runoff events in agricultural areas in south-west France [PDF]
, 2011 When heavy rainfall follows herbicide application, the intense surface runoff causes stream water contamination. Aquatic organisms are then briefly exposed to a complex mixture of contaminants.
Gauthier, Laury +6 more
core +2 more sources
Is there a causal association between genotoxicity and the imposex effect? [PDF]
, 2006 There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger +13 more
core +2 more sources
Genotoxic potential of 10% and 16% Carbamide Peroxide in dental bleaching
Brazilian Oral Research, 2015 Dental bleaching has become one of the most frequently requested esthetic treatments in dental offices. Despite the high clinical success observed with this procedure, some adverse effects have been reported, including a potential for developing ...
Aline Ferreira de ALMEIDA +6 more
doaj +1 more source
Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]
, 2014 The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S. +9 more
core +2 more sources
Assessment of methyl methacrylate genotoxicity by the micronucleus test
Brazilian Oral Research, 2013 The aim of this study was to evaluate the genotoxic potential of methyl methacrylate (MMA) vapor by simulating standard occupational exposure of 8 hours per day and using the micronucleus test. We used 32 adult male Wistar rats divided into three groups:
Amarildo Mariano de Araújo +4 more
doaj +1 more source
Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review. [PDF]
J Appl ToxicolABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Pinto TG +6 more
europepmc +2 more sources
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]
, 2010 Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel +2 more
core +2 more sources
Acute Oral Toxicity and Genotoxicity Test and Evaluation of Cinnamomum camphora Seed Kernel Oil
Foods, 2023 Cinnamomum camphora seed kernel oil (CCSKO) is one of the important natural medium chain triglycerides (MCT) resources, with more than 95.00% of medium chain fatty acids found in the world, and has various physiological effects.
Pengbo Wang +10 more
doaj +1 more source