Results 11 to 20 of about 3,879 (89)

MicroRNA-630 alleviates inflammatory reactions in rats with diabetic kidney disease by targeting toll-like receptor 4. [PDF]

World J Diabetes
BACKGROUND Diabetic kidney disease (DKD) is a major complication of diabetes mellitus. Renal tubular epithelial cell (TEC) damage, which is strongly associated with the inflammatory response and mesenchymal trans-differentiation, plays a significant role in DKD; However, the precise molecular mechanism is unknown.
Wu QS, Zheng DN, Ji C, Qian H, Jin J, He Q.   +5 more
europepmc   +3 more sources

miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis. [PDF]

Biol Direct
Background MicroRNAs (miRNAs) are critical regulators of cancer progression, prompting our investigation into the specific function of miR-630 in pancreatic cancer stem cells (PCSCs).
Zou J, Yang S, He C, Deng L, Xu B, Chen S.   +5 more
europepmc   +2 more sources

miR-378a-5p and miR-630 induce lens epithelial cell apoptosis in cataract via suppression of E2F3 [PDF]

Brazilian Journal of Medical and Biological Research, 2020
Cataract, an eye disease that threatens the health of millions of people, brings about severe economic burden for patients and society. MicroRNA (miR)-378a-5p and miR-630 were recognized as essential regulators in multiple cancers.
Weiwei Gao, Xiaoqing Zhou, Ruihua Lin
doaj   +1 more source

HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop

Journal of Immunology Research, 2022
Purpose. Hypoxia has crucial functions in the development and metastasis of cervical cancer by inducing the expression of numerous genes, including microRNA genes.
Qiaohui Gao, Zhenghua Ren, Shengyuan Jiao, Juan Guo, Xia Miao, Jin Wang, Junye Liu   +6 more
doaj   +1 more source

RETRACTED: Tumor-Derived Extracellular Vesicles Promote Activation of Carcinoma-Associated Fibroblasts and Facilitate Invasion and Metastasis of Ovarian Cancer by Carrying miR-630

Frontiers in Cell and Developmental Biology, 2021
Ovarian cancer (OC) is a lethal gynecological malignancy. Extracellular vesicles (EVs) are crucial media in cell-to-cell communication by carrying microRNAs (miRs).
Yulan Cui, Deying Wang, Min Xie
doaj   +1 more source

MicroRNA expression profiles of whole blood in lung adenocarcinoma. [PDF]

PLoS ONE, 2012
The association of lung cancer with changes in microRNAs in plasma shown in multiple studies suggests a utility for circulating microRNA biomarkers in non-invasive detection of the disease.
Santosh K Patnaik, Sai Yendamuri, Eric Kannisto, John C Kucharczuk, Sunil Singhal, Anil Vachani   +5 more
doaj   +1 more source

Relationship Between Coronary Atheroma, Epicardial Adipose Tissue Inflammation, and Adipocyte Differentiation Across the Human Myocardial Bridge

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Inflammation in epicardial adipose tissue (EAT) may contribute to coronary atherosclerosis. Myocardial bridge is a congenital anomaly in which the left anterior descending coronary artery takes a “tunneled” course under a bridge of myocardium:
Tracey McLaughlin, Ingela Schnittger, Anna Nagy, Elizabeth Zanley, Yue Xu, Yanqiu Song, Koen Nieman, Jennifer A. Tremmel, Damini Dey, Jack Boyd, Harold Sacks   +10 more
doaj   +1 more source

Molecular genetics of idiopathic pulmonary fibrosis

Вавиловский журнал генетики и селекции, 2022
Idiopathic pulmonary fibrosis (IPF) is a severe progressive interstitial lung disease with a prevalence of 2 to 29 per 100,000 of the world’s population. Aging is a significant risk factor for IPF, and the mechanisms of aging (telomere depletion, genomic
R. N. Mustafin
doaj   +1 more source

The role of miRNA and lncRNA in heterotopic ossification pathogenesis

Stem Cell Research & Therapy, 2022
Heterotopic ossification (HO) is the formation of bone in non-osseous tissues, such as skeletal muscles. The HO could have a genetic or a non-genetic (acquired) background, that is, it could be caused by musculoskeletal trauma, such as burns, fractures ...
Łukasz Pulik, Bartosz Mierzejewski, Aleksandra Sibilska, Iwona Grabowska, Maria Anna Ciemerych, Paweł Łęgosz, Edyta Brzóska   +6 more
doaj   +1 more source

MicroRNA-630 is a prognostic marker for patients with colorectal cancer

Tumor Biology, 2014
MicroRNAs are noncoding RNAs that regulate multiple cellular processes during cancer progression. Among various microRNAs, miR-630 has recently been identified to be implicated in many critical processes in human malignancies. We investigated the expression pattern and prognostic value of miR-630 in human colorectal cancer by utilizing cancer and ...
Dake, Chu, Jianyong, Zheng, Jipeng, Li, Yunming, Li, Jian, Zhang, Qingchuan, Zhao, Weizhong, Wang, Gang, Ji   +7 more
openaire   +2 more sources