Results 41 to 50 of about 335,784 (179)
Neuron, 2023 Cortical projection neurons polarize and form an axon while migrating radially. Even though these dynamic processes are closely interwoven, they are regulated separately-the neurons terminate their migration when reaching their destination, the cortical ...
Stanislav Vinopal +12 more
semanticscholar +1 more source
Microtubule nucleation at the centrosome and beyond [PDF]
Nature Cell Biology, 2015 Microtubule polymerization is initiated by γ-tubulin containing complexes. Petry and Vale discuss factors involved in localizing and activating γ-tubulin at different locations in the cell.
Petry, Sabine, Vale, Ronald D
openaire +4 more sources
Cell edges accumulate gamma tubulin complex components and nucleate microtubules following cytokinesis in Arabidopsis thaliana. [PDF]
PLoS ONE, 2011 Microtubules emanate from distinct organizing centers in fungal and animal cells. In plant cells, by contrast, microtubules initiate from dispersed sites in the cell cortex, where they then self-organize into parallel arrays.
Chris Ambrose, Geoffrey O Wasteneys
doaj +1 more source
The actin regulator profilin 1 is functionally associated with the mammalian centrosome
Life Science Alliance, 2021 The actin regulator profilin 1 recently shown to control microtubule elongation at the cell periphery is found to interact with the γ-tubulin ring complex and tune centrosomal microtubule nucleation.
Michaela Nejedlá +6 more
doaj +1 more source
Nucleation and Dynamics of Golgi-derived Microtubules [PDF]
Frontiers in Neuroscience, 2015 Integrity of the Golgi apparatus requires the microtubule (MT) network. A subset of MTs originates at the Golgi itself, which in this case functions as a MT-organizing center (MTOC). Golgi-derived MTs serve important roles in post-Golgi trafficking, maintenance of Golgi integrity, cell polarity and motility, as well as cell type-specific functions ...
Sanders, Anna A. W. M., Kaverina, Irina
openaire +3 more sources
CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre
bioRxiv, 2021 Microtubules are dynamic polymers consisting of αβ-tubulin heterodimers. The initial polymerization process, called microtubule nucleation, occurs spontaneously via αβ-tubulin.
T. Imasaki +19 more
semanticscholar +1 more source
Augmin-dependent microtubule nucleation at microtubule walls in the spindle [PDF]
Journal of Cell Biology, 2013 The formation of a functional spindle requires microtubule (MT) nucleation from within the spindle, which depends on augmin. How augmin contributes to MT formation and organization is not known because augmin-dependent MTs have never been specifically visualized.
Kamasaki, Tomoko +6 more
openaire +3 more sources
Integrated model of the vertebrate augmin complex
Nature Communications, 2023 Accurate segregation of chromosomes is required to maintain genome integrity during cell division. This feat is accomplished by the microtubule-based spindle.
Sophie M. Travis +8 more
doaj +1 more source
Cells, 2021 Higher plants represent a large group of eukaryotes where centrosomes are absent. The functions of γ-tubulin small complexes (γ-TuSCs) and γ-tubulin ring complexes (γ-TuRCs) in metazoans and fungi in microtubule nucleation are well established and the ...
Jana Chumová +4 more
doaj +1 more source
The plant Spc98p homologue colocalizes with γ-tubulin at microtubule nucleation sites and is required for microtubule nucleation [PDF]
Journal of Cell Science, 2002 The molecular basis of microtubule nucleation is still not known in higher plant cells. This process is better understood in yeast and animals cells. In the yeast spindle pole body and the centrosome in animal cells,γ-tubulin small complexes and γ-tubulin ring complexes,respectively, nucleate all microtubules.
Erhardt, Mathieu +10 more
openaire +3 more sources