Results 41 to 50 of about 25,411 (262)
Selection of a mineralocorticoid receptor antagonist for patients with hypertension or heart failure [PDF]
, 2014 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102661/1/ejhf31 ...
Beck +65 more
core +2 more sources
The melanocortin receptors and their accessory proteins. [PDF]
, 2013 The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF +3 more
core +2 more sources
Mineralocorticoid Receptor Antagonist for Renal Protection
Renal Failure, 2012 The renin-angiotensin system (RAS) plays an important role in the pathophysiology of cardiovascular and renal diseases. In chronic kidney disease (CKD), blockade of RAS by angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) has been shown to reduce proteinuria and retard the progression of renal function deterioration ...
Terry King-Wing, Ma, Cheuk-Chun, Szeto
openaire +2 more sources
Treatment and practical considerations of diabetic kidney disease
Frontiers in Medicine, 2023 Diabetic kidney disease (DKD) is a complication of diabetes that can lead to kidney failure. Over the years, several drugs have been developed to combat this disease.
Yara Bilen +5 more
doaj +1 more source
Adipocytes, aldosterone and obesity-related hypertension [PDF]
, 2016 Understanding the mechanisms linking obesity with hypertension is important in the current obesity epidemic as it may improve therapeutic interventions.
Friederich-Persson, Malou +3 more
core +1 more source
Regulation of Klotho Production by Mineralocorticoid Receptor Signaling in Renal Cell Lines
BiomoleculesThrough the mineralocorticoid receptor, aldosterone controls extracellular volume and arterial blood pressure by stimulating Na+ absorption and K+ secretion in epithelial cells of the kidney, colon, and several glands.
Elena Kohm +2 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2015 Despite the availability of anti-hypertensive medications with increasing efficacy up to 50% of hypertensive patients have blood pressure levels (BP) not at the goals set by international societies.
Giuseppe eMaiolino +2 more
doaj +1 more source
Hypertension: Renin-Angiotensin-Aldosterone System Alterations [PDF]
, 2015 Blockers of the renin-angiotensin-aldosterone system (RAAS), that is, renin inhibitors, angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists, and mineralocorticoid receptor antagonists, are a cornerstone in the ...
Danser, A.H.J. (Jan) +4 more
core +1 more source
Eplerenone in the Treatment of Polypoidal Choroidal Vasculopathy
Case Reports in Ophthalmology, 2015 Overactivation of mineralocorticoid receptor pathways has been implicated in the pathophysiology of central serous chorioretinopathy (CSCR). Recently, mineralocorticoid receptor antagonists such as eplerenone have demonstrated success in treating ...
Kapil G. Kapoor, Alan L. Wagner
doaj +1 more source
Epidermal mineralocorticoid receptor plays beneficial and adverse effects in skin and mediates glucocorticoid responses [PDF]
, 2016 10 páginas, 6 figuras. Contiene material suplementarioGlucocorticoids (GCs) regulate skin homeostasis and combat cutaneous inflammatory diseases; however, adverse effects of chronic GC treatments limit their therapeutic use.
Boix, Julia +4 more
core +1 more source