Results 31 to 40 of about 36,419 (163)

HIF-1α Stabilization Increases miR-210 Eliciting First Trimester Extravillous Trophoblast Mitochondrial Dysfunction

Frontiers in Physiology, 2019
Preeclampsia is associated with first trimester placental dysfunction. miR-210, a small non-coding RNA, is increased in the preeclamptic placenta. The effects of elevated miR-210 on placental function remain unclear.
Lauren Anton, Ann DeVine, Erzsebet Polyak, Anthony Olarerin-George, Amy G. Brown, Marni J. Falk, Michal A. Elovitz   +6 more
doaj   +1 more source

PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells [PDF]

, 2014
PLC-beta 1 (PLCβ1) inhibits in human K562 cells erythroid differentiation induced by mithramycin (MTH) by targeting miR-210 expression. Inhibition of miR-210 affects the erythroid differentiation pathway and it occurs to a greater extent in MTH-treated ...
Bavelloni, Alberto, Blalock, William, Cocco, Lucio, Faenza, Irene, Fiume, Roberta, Matteucci, Alessandro, McCubrey, James A., NC DOCKS at East Carolina University, Poli, Alessandro, Ramazzotti, Giulia   +9 more
core   +2 more sources

miR-210: fine-tuning the hypoxic response [PDF]

, 2014
Hypoxia is a central component of the tumor microenvironment and represents a major source of therapeutic failure in cancer therapy. Recent work has provided a wealth of evidence that noncoding RNAs and, in particular, microRNAs, are significant members ...
A Allegra, A Giannakakis, A Hüttenhofer, A Krek, A Shinohara, A Ventura, A Zhao, AC Koong, AE Pasquinelli, AM Cheng, AS Ho, B Malzkorn, B Wightman, BE Baysal, BJ Reinhart, BL Pineles, BP Lewis, BP Lewis, C Camps, C Devlin, C Nakada, C-C Chio, CH Lawrie, D Baek, D Betel, D Gou, D Hanahan, D Juan, DA Enquobahrie, DA Landau, DD Taylor, DP Bartel, DP Bartel, DS Schwarz, E Balsa, E Bostjancic, E Fabbri, E Fabbri, E Favaro, E Gottlieb, E Miko, E Rooij van, EJ Jung, F Mochel, F Rothe, F Wu, FE Benson, FV Karginov, G Leone, G Meroni, G Wan, GA Calin, GL Semenza, GL Semenza, GL Semenza, GL Semenza, GL Wang, GL Wang, GL Wang, H Antonicka, H Guo, H Iguchi, H Valadi, H Zhang, H-Y Chen, HE Gee, HW Kim, HW Kim, HW King, I Satzger, J Brugarolas, J He, J Lu, J Sarkar, J Stenvang, J Tabernero, J Wang, JA Foekens, JA Lees, JA Weber, JC Presti Jr, JC Venter, JD Gordan, JM Brown, JR Gnarra, JW Kim, K Jeyaseelan, K Pulkkinen, K Ruan, KP Porkka, L Cicchillitti, L Hong, L Qin, L Salmena, LP Lim, M Ivan, M Kertesz, M Liu, M Maragkakis, M Raponi, M Redova, M Selbach, MA Alaiti, MA Cortez, MA Valencia-Sanchez, ME Crosby, MP Murphy, MP Puissegur, MV Iorio, MV Iorio, MZ Michael, N Bushati, N Yanaihara, NC Denko, NC Denko, NL Simone, NMA White, O Bunoust, P Fasanaro, P Fasanaro, P Fasanaro, P Jaakkola, P Vaupel, PJ Hurlin, PS Mitchell, R Bindra, R Faraonio, R Gambari, R Garzon, R Kulshreshtha, R Kulshreshtha, RA Gatenby, RB Donker, RC Lee, RD Guzy, RE Lanford, RF Place, RK Mutharasan, S Biswas, S Djebali, S Djuranovic, S Djuranovic, S Gilad, S Greco, S Griffiths-Jones, S Hammer, S Hu, S Krick, S Kuijper, S Tsuchiya, S Vasudevan, S Wang, SA Ciafre, SY Chan, T Greither, T Greither, T Kawamata, T Li, T Thum, T Toyama, TJ Kelly, W Yang, W Zundel, WH Tong, WR Wilson, X Chen, X Huang, X Huang, X Zhang, XM Zhu, Y Lee, Y Lee, Y Liu, Y Liu, Y Mizuno, Y Murakami, Y Nakamura, Y Nie, YL Lou, Z Chen, Z Zhang   +180 more
core   +1 more source

MicroRNA-210 induces apoptosis in colorectal cancer via induction of reactive oxygen [PDF]

, 2016
Additional file 2: Figure S2. Representative flow cytometric histograms of CRC cell lines 72 h post transfection with pre-miR-210 and a control miRNA, respectively.
Anne Fassl, Jutta Richter, Katrin E. Tagscherer, Sabrina Schecher, Stephan Macher-Goeppinger, Tabea Sinkovic, Wilfried Roth   +6 more
core   +4 more sources

MicroRNA-210 and endoplasmic reticulum chaperones in the regulation of chemoresistance in glioblastoma [PDF]

, 2015
Glioblastoma multiforme (GBM) is the commonest primary brain tumour in adults characterized by relentless recurrence due to resistance towards the standard chemotherapeutic agent temozolomide (TMZ).
Fung, CF, Ho, ASW, Kiang, KMY, Lee, D, Leung, GKK, Lui, WM, Sun, S, Zhang, PD, Zhang, XQ   +8 more
core   +1 more source

MicroRNA-210-5p Contributes to Cognitive Impairment in Early Vascular Dementia Rat Model Through Targeting Snap25

Frontiers in Molecular Neuroscience, 2018
Vascular dementia (VD) is the most common form of dementia in elderly people. However, little is understood about the role of microRNAs (miRNAs) involved in cognitive impairment in early VD. Here, a VD model induced by chronic cerebral ischemia and fetal
Zhenxing Ren, Junlong Yu, Zimei Wu, Wenwen Si, Xianqian Li, Yuqing Liu, Jianhong Zhou, Rudong Deng, Dongfeng Chen   +8 more
doaj   +1 more source

MicroRNA response to hypoxic stress in soft tissue sarcoma cells: MicroRNA mediated regulation of HIF3α [PDF]

, 2014
Background: Hypoxia is often encountered in solid tumors and known to contribute to aggressive tumor behavior, radiation- and chemotherapy resistance resulting in a poor prognosis for the cancer patient.
Gits, C.M.M. (Caroline), IJcken, W.F.J. (Wilfred) van, Jonkers, M.B.E., Kuijk, P.F. (Patricia) van, Mathijssen, A.H.J. (Ron), Muskens, N. (Nikky), Rijck, J.C.W.M. (Jonneke) de, Sleijfer, S. (Stefan), Verweij, J. (Jaap), Wiemer, E.A.C. (Erik)   +9 more
core   +1 more source

Radiogenomics in clear cell renal cell carcinoma: correlations between advanced CT imaging (texture analysis) and microRNAs expression [PDF]

, 2019
Purpose: A relevant challenge for the improvement of clear cell renal cell carcinoma management could derive from the identification of novel molecular biomarkers that could greatly improve the diagnosis, prognosis, and treatment choice of these ...
Badia, S., Bellini, D., Carbone, A., Caruso, D., Fazi, F., Laghi, A., Marigliano, C., Miglietta, S., Palleschi, G., Pastore, A. L., Petrozza, V., Rengo, M., Tito, C.   +12 more
core   +1 more source

Hypoxia-Induced MicroRNA-210 Targets Neurodegenerative Pathways

Non-Coding RNA, 2018
Hypoxia-regulated microRNA-210 (miR-210) is a highly conserved microRNA, known to regulate various processes under hypoxic conditions. Previously we found that miR-210 is also involved in honeybee learning and memory, raising the questions of how neural ...
Michelle E. Watts, Sarah M. Williams, Jess Nithianantharajah, Charles Claudianos   +3 more
doaj   +1 more source

Serum miR-210 Contributes to Tumor Detection, Stage Prediction and Dynamic Surveillance in Patients with Bladder Cancer. [PDF]

PLoS ONE, 2015
MiR-210 is the master hypoxamir that generally exhibits oncogenic properties in most human solid tumors including bladder cancer (BC). However, it remains unknown about the clinical significance of circulating miR-210 levels in BC.
Yongmei Yang, Ailin Qu, Jingkang Liu, Rui Wang, Yingjie Liu, Gang Li, Weili Duan, Qian Fang, Xiumei Jiang, Lili Wang, Guixi Zheng, Lutao Du, Xin Zhang, Chuanxin Wang   +13 more
doaj   +1 more source