Co-expression of miRNA players in advanced laryngeal carcinoma – Insights into the roles of miR-93-5p, miR-145-5p, and miR-210-3p [PDF]
Biomolecules & BiomedicineAdvanced laryngeal squamous cell carcinoma (LSCC) is the second most prevalent type of head and neck squamous cell carcinoma (HNSCC). Identifying microRNAs (miRNAs) related to key regulatory molecules or mechanisms could offer an alternative approach to
Silva Kyurkchiyan +8 more
doaj +5 more sources
miR-210-3p protects against osteoarthritis through inhibiting subchondral angiogenesis by targeting the expression of TGFBR1 and ID4 [PDF]
Frontiers in Immunology, 2022 Excessive subchondral angiogenesis is a key pathological feature of osteoarthritis (OA), as it alters the balance of subchondral bone remodeling and causes progressive cartilage degradation.
Han Tang +6 more
doaj +2 more sources
CPEB2 Suppresses Hepatocellular Carcinoma Epithelial–Mesenchymal Transition and Metastasis through Regulating the HIF-1α/miR-210-3p/CPEB2 Axis [PDF]
Pharmaceutics, 2023 Hepatocellular carcinoma (HCC) is a prevalent and high-mortality cancer worldwide, and its complexity necessitates novel strategies for drug selection and design.
Ran You +8 more
doaj +2 more sources
miR-210-3p suppresses osteogenic differentiation of MC3T3-E1 by targeting brain derived neurotrophic factor (BDNF) [PDF]
Journal of Orthopaedic Surgery and Research, 2022 Background and objective As an important mediator of intercellular interaction and formation of extracellular bone matrix, porous scaffolds are widely used for bone regeneration.
Li Deng +5 more
doaj +2 more sources
Paracrine effects of mir-210-3p on angiogenesis in hypoxia-treated c-kit-positive cardiac cells [PDF]
Annals of Medicine, 2023 Objective: Treatment with c-kit-positive cardiac cells (CPCs) has been shown to improve the prognosis of ischemic heart disease. MicroRNAs (miRNAs) confer protection by enhancing the cardiac repair process, but their specific functional mechanisms remain
Louyi Shen +4 more
doaj +2 more sources
MicroRNA-210-3p Targets RGMA to Enhance the Angiogenic Functions of Endothelial Progenitor Cells Under Hypoxic Conditions [PDF]
Frontiers in Cellular Neuroscience, 2019 Endothelial progenitor cells (EPCs) are multipotential stem cells considered to have immense clinical value for revascularization. However, the clinical application of EPCs has been hampered by their clinical potency in ischemic anoxic environments. This
Wen-Jing Lu +9 more
doaj +3 more sources
Long Non-coding RNA DLEU2L Targets miR-210-3p to Suppress Gemcitabine Resistance in Pancreatic Cancer Cells via BRCA2 Regulation [PDF]
Frontiers in Molecular Biosciences, 2021 Gemcitabine (GEM) resistance remains a challenging clinical issue to overcome in chemotherapy against pancreatic cancer. We previously demonstrated that miR-210 derived from pancreatic cancer stem cells enhanced the GEM-resistant properties of pancreatic
Fei Xu +3 more
doaj +2 more sources
The Role of miR-375-3p, miR-210-3p and Let-7e-5p in the Pathological Response of Breast Cancer Patients to Neoadjuvant Therapy [PDF]
Medicina, 2022 Background and Objectives: Prediction of response to therapy remains a continuing challenge in treating breast cancer, especially for identifying molecular tissue markers that best characterize resistant tumours.
Lorena Alexandra Lisencu +12 more
doaj +2 more sources
Hsa-miR-210-3p expression in breast cancer and its putative association with worse outcome in patients treated with Docetaxel. [PDF]
Sci Rep, 2019 MicroRNA-210-3p is the most prominent hypoxia regulated microRNA, and it has been found significantly overexpressed in different human cancers. We performed the expression analysis of miR-210-3p in a retrospective cohort of breast cancer patients with a ...
Pasculli B +13 more
europepmc +9 more sources
Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer [PDF]
Biomedicines, 2021 MiRNAs play a relevant role in PC (prostate cancer) by the regulation in the expression of several pathways’ AR (androgen receptor), cellular cycle, apoptosis, MET (mesenchymal epithelium transition), or metastasis.
Luis Javier Martínez-González +8 more
doaj +4 more sources