Results 171 to 180 of about 15,193 (187)
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miR-210-3p Impairs Pancreatic β-Cell Function by Targeting Dtx1 in Gestational Diabetes Mellitus

Journal of Environmental Pathology, Toxicology and Oncology, 2022
Gestational diabetes mellitus (GDM), a common complication in pregnancy, could threaten the health of both pregnancies and their offspring. miR-210-3p has been reported that play a crucial role in many diseases. Nevertheless, the molecular mechanism and clinical significance of miR-210-3p in the GDM is still unclear. miR-210-3p was overexpressed in the
Xiaohui, Cao   +5 more
openaire   +2 more sources

In silico analysis reveals hypoxia-induced miR-210-3p specifically targets SARS-CoV-2 RNA

Journal of Biomolecular Structure and Dynamics, 2023
Human coronaviruses (HCoVs) until the emergence of SARS in 2003 were associated with mild cold and upper respiratory tract infections. The ongoing pandemic caused by SARS-CoV-2 has enhanced the potential for infection and transmission as compared to other known members of this family.
Mirza Sarwar Baig   +4 more
openaire   +2 more sources

Quantification of circulating miR-517c-3p and miR-210-3p levels in preeclampsia

Pregnancy Hypertension, 2019
MicroRNAs (miRNAs, miRs) are small regulatory non-coding RNAs that regulate gene expression by incomplete complementary attachment to the 3'UTR, 5'UTR, ORF and promoter regions of target mRNAs. We compared plasma levels of miR-210-3p and miR-517c-3p as cell-free microRNAs (cfmiRNAs) in preeclamptic (n = 20) and healthy women (n = 20).
Reza Mola Ali Nejad   +4 more
openaire   +2 more sources

MiR-210-3p targets CELF2 to facilitate progression of lung squamous carcinoma through PI3K/AKT pathway

Medical Oncology, 2022
This study examined the internal mechanism of miR-210-3p/CELF2 in LUSC. Expression data of mRNAs and miRNAs in LUSC were acquired from TCGA and subjected to differential expression analysis. qRT-PCR was applied to examine miR-210-3p and CELF2 expression.
Qiang Zhang, Yunzhen Wang
openaire   +2 more sources

Seminal exosomal miR‐210‐3p as a potential marker of Sertoli cell damage in Varicocele

Andrology, 2020
AbstractBackgroundVaricocoele‐associated stressors, such as hypoxia and heat, can damage cell function and viability, and some exosomal biomarkers released from impaired cells may reflect the cell status in testis.ObjectivesTo find if seminal exosomal microRNAs can reflect the Sertoli cell function in varicocoele.Materials and methodsExperimental left ...
Yi Ma   +6 more
openaire   +2 more sources

Seminal plasma miR‐210‐3p is a biomarker for screening dyszoospermia caused by varicocele

Andrologia, 2019
To evaluate the value of seminal plasma miR-210-3p as a novel and non-invasive biomarker for screening dyszoospermia caused by varicocele. Semen samples from patients with varicocele and healthy males were collected for semen analysis and quantitative real-time polymerase chain reaction.
Yawei Xu   +4 more
openaire   +2 more sources

Serum miR-210-3p as a Potential Noninvasive Biomarker of Lung Adenocarcinoma: A Preliminary Study

Genetic Testing and Molecular Biomarkers, 2019
Background: Development of noninvasive biomarkers could potentially contribute to extending the 5-year overall survival rate of nonsmall cell lung cancer (NSCLC) patients. Circulating microRNAs (miRNAs), due to their high stability, have the potential to become valuable cancer biomarkers.
Weronika Zofia, Świtlik   +4 more
openaire   +2 more sources

Omega-3 fatty acid protects cardiomyocytes against hypoxia-induced injury through targeting MiR-210-3p/CASP8AP2 axis

Molecular and Cellular Biochemistry, 2021
MicroRNAs (miRs) regulate diverse biological functions in both normal and pathological cellular conditions by post-transcriptional regulation of various genes expression. Nevertheless, the role of miRs in regulating the protective functions of omega-3 fatty acid in relation to hypoxia in cardiomyocytes remains unknown.
Xueju Yu   +8 more
openaire   +2 more sources

Emerging role of secreted miR-210-3p as potential biomarker for clear cell Renal Cell Carcinoma metastasis

Cancer Biomarkers, 2020
BACKGROUND: MicroRNAs (miRNAs) are emerging as promising molecules in the diagnosis, prognosis and treatment of urological tumours. Recently, our group performed two independent studies highlighting that miR-210-3p may be a useful biomarker not only for diagnosis but also for post-surgery clear cell Renal Cell Carcinoma (ccRCC) management.
Petrozza, Vincenzo   +13 more
openaire   +2 more sources

Placental expression of miR-21-5p, miR-210-3p and miR-141-3p: relation to human fetoplacental growth

European Journal of Clinical Nutrition, 2021
Dysregulation of microRNAs (miRNAs) and their target genes in placental tissue is associated with foetal growth restriction. We aimed to evaluate associations of placental miR-21-5p, miR-141-3p and miR-210-3p expression with maternal, placental and newborn parameters and with placental expression of their potential target genes PTEN, VEGF, FLT and ENG ...
P. Kochhar   +7 more
openaire   +2 more sources

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