Results 161 to 170 of about 367,365 (231)

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, Volume 2, Issue 2, Page 236-279, June 2026.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

miR-526b-3p serves as a prognostic factor and regulates the proliferation, invasion, and migration of glioma through targeting WEE1

, 2019
Ming Wu, Xuejun Li, Qing Liu, Yuanyang Xie, Jian Yuan, Siyi WanggouDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of ChinaBackground: MicroRNAs play important roles in cancer progression ...
Li X, Wu M, Xie Y, Liu Q, Yuan J, Wanggou S   +5 more
core  

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, Volume 2, Issue 2, Page 343-370, June 2026.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong, Jieni Li, Mingxuan Pan, Xiaoxue Ke, Hongjuan Cui   +4 more
wiley   +1 more source

Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi, Xi Liu, Xi Zhang, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

In-situ growth of heterogeneous Au on MoS₂ nanosheets for SERS detection of breast cancer-derived miR-210-3p and miR-9-3p. [PDF]

Sci Rep
Zablon FM, Pathiraja G, Dellinger K, Aravamudhan S.   +3 more
europepmc   +1 more source

Investigating the Phytochemical Constituents, Anti‐Inflammatory, and Neuropharmacological Activities of Podocarpus neriifolius Leaves Through FT‐IR, GC–MS, Experimental Studies, Molecular Docking, and Molecular Dynamics Simulations

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Podocarpus neriifolius, a widely distributed medicinal plant in South and Southeast Asia, has traditionally been used to treat rheumatism and joint pain. This study aimed to investigate the phytochemical profile and therapeutic potential of the ethanolic leaf extract of P.
Neamul Hoque, Md. Tashrif Rahman Tipu, Md Abul Bashar, Raju Dash, Kutub Uddin Ahamed, Md. Liakot Ali, Md. Jahirul Islam Mamun, Bakul Akter, Mohammed Kamrul Hossain, Nawreen Monir Proma   +9 more
wiley   +1 more source

miR-142-3p suppresses uveal melanoma by targeting CDC25C, TGFβR1, GNAQ, WASL, and RAC1

, 2019
Dewei Peng,1,2 Jing Dong,1,2 Yunping Zhao,1,2 Xiaomei Peng,1,2 Jingjing Tang,1,2 Xiaoyan Chen,1,2 Lihua Wang,1,2 Dan-Ning Hu,2,3 Peter S Reinach,1,2 Jia Qu,1,2 Dongsheng Yan1,21School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical ...
Peng X, Tang J, Hu DN, Reinach PS, Peng D, Dong J, Qu J, Yan D, Chen X, Zhao Y, Wang L   +10 more
core  

Dehydrogenation Thermodynamic and Kinetic Challenges of Mg‐Ni‐Based Alloy Hydrides

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Solid‐state hydrogen storage stands as a pivotal, safe, and efficient solution for the future hydrogen economy. Among diverse hydrogen storage systems, Mg‐Ni‐based alloy hydrides are recognized as cornerstone materials. However, their practical application is hindered by two core challenges: the high thermodynamic stability of the hydride ...
Jinglan He, Jie Tian, Xiaojiang Hou, Yuyang Zhao, Wenfeng Li, Bolong Huang, Hu Liu   +6 more
wiley   +1 more source