Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma. [PDF]
Oncotarget, 2017 The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Petrozza V +12 more
europepmc +8 more sources
Elevation of circulating miR-210-3p in high-altitude hypoxic environment [PDF]
Frontiers in Physiology, 2016 Background: The induction of miR-210-3p, a master hypoxamir, is a consistent feature of the hypoxic response in both normal and malignant cells. However, whether miR-210-3p acts as a circulating factor in response to a hypoxic environment remains unknown.
Yan eYan +10 more
doaj +5 more sources
Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele [PDF]
Asian Journal of Andrology, 2020 The aim of this study was to investigate the role of seminal plasma miR-210-3p in the impairment of semen quality caused by varicocele. This study included 102 patients whose semen quality was normal when they were diagnosed with varicocele.
Ya-Wei Xu +7 more
doaj +4 more sources
miR-210-3p enriched extracellular vesicles from hypoxic neuroblastoma cells stimulate migration and invasion of target cells [PDF]
Cell & Bioscience, 2023 Background Tumor hypoxia stimulates release of extracellular vesicles (EVs) that facilitate short- and long-range intercellular communication and metastatization. Albeit hypoxia and EVs release are known features of Neuroblastoma (NB), a metastasis-prone
Pina Fusco +9 more
doaj +4 more sources
Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1 [PDF]
Cell & Bioscience, 2018 Background ATP-binding cassette transporter super-family including ABCC1 and MDR-1 were involved in multi-drug resistance (MDR) of renal cell carcinoma (RCC) patients.
Songchao Li +6 more
doaj +5 more sources
Hypoxia‐induced miR‐210‐3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2 mediated monocyte infiltration [PDF]
Molecular OncologyIn most cancers, tumor hypoxia downregulates the expression of C‐C motif chemokine 2 (CCL2), and this downregulation has been implicated in monocyte infiltration and tumor progression; however, the molecular mechanism is not yet clear.
Leena Arora +8 more
doaj +2 more sources
Study on the mechanism and clinical value of miR-210-3p and miR-582-5p in acute myocardial infarction by targeting MXD1 [PDF]
Journal of Cardiothoracic SurgeryBackground Acute myocardial infarction (AMI) occurs rapidly and is a major cause of death in patients with coronary artery disease (CAD). To explore new biomarkers of AMI and its pathogenesis.
Shanshan Liu, Jing Han, Shufang Gao
doaj +2 more sources
Expression of miR-210-3p as a Prognostic Marker for Development of Diabetic Neuropathy [PDF]
MetabolitesBackground/Objectives: Diabetic neuropathy (DN) is one of the most common complications of type 2 diabetes mellitus (T2DM), involving complex metabolic, vascular, and epigenetic mechanisms. MicroRNA-210-3p (miR-210-3p), a hypoxia-responsive molecule, has
Savelia G. Yordanova +12 more
doaj +2 more sources
Effects of miR-210-3p/SDF2 and miR-31-5p/FGF7 from hypoxic endometrial exosomes on UCB-MSC proliferation, migration, and differentiation [PDF]
Stem Cell Research & TherapyBackground Mesenchymal stem cells (MSCs) isolated from umbilical cord blood (UCB) exhibit significant therapeutic efficacy in endometriosis; however, the molecular mechanisms governing their regulation remain incompletely elucidated.
Simiao Liu +3 more
doaj +2 more sources
Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway [PDF]
Molecular Cancer, 2017 Background The primary issue arising from prostate cancer (PCa) is its high prevalence to metastasize to bone, which severely affects the quality of life and survival time of PCa patients.
Dong Ren +6 more
doaj +3 more sources