Results 41 to 50 of about 15,193 (187)

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA, CARBONE, Antonio, DELLA ROCCA, Carlo, DI CARLO, ANGELINA, FAZI, Francesco, PALLESCHI, GIOVANNI, PASTORE, ANTONIO LUIGI, PETROZZA, Vincenzo, PORTA, NATALE   +8 more
core   +2 more sources

MicroRNA response to hypoxic stress in soft tissue sarcoma cells: MicroRNA mediated regulation of HIF3α [PDF]

, 2014
Background: Hypoxia is often encountered in solid tumors and known to contribute to aggressive tumor behavior, radiation- and chemotherapy resistance resulting in a poor prognosis for the cancer patient.
Gits, C.M.M. (Caroline), IJcken, W.F.J. (Wilfred) van, Jonkers, M.B.E., Kuijk, P.F. (Patricia) van, Mathijssen, A.H.J. (Ron), Muskens, N. (Nikky), Rijck, J.C.W.M. (Jonneke) de, Sleijfer, S. (Stefan), Verweij, J. (Jaap), Wiemer, E.A.C. (Erik)   +9 more
core   +1 more source

Plasma microrna expression profile for reduced ejection fraction in dilated cardiomyopathy [PDF]

, 2021
The left ventricular (LV) ejection fraction (EF) is key to prognosis in dilated cardiomyopathy (DCM). Circulating microRNAs have emerged as reliable biomarkers for heart diseases, included DCM.
Belmonte, Thalia, Calderón Domínguez, María, Calderón-Domínguez, Juan, Campuzano, Oscar, Mangas Rojas, Alipio, Quezada‑Feijoo, Maribel, Ramos, Mónica, Toro Cebada, Rocío   +7 more
core   +1 more source

Small RNA sequencing reveals metastasis-related microRNAs in lung adenocarcinoma [PDF]

, 2017
The majority of lung cancer deaths are caused by metastatic disease. MicroRNAs (miRNAs) are posttranscriptional regulators of gene expression and miRNA dysregulation can contribute to metastatic progression. Here, small RNA sequencing was used to profile
Daugaard, Iben, Hager, Henrik, Hansen, Lise Lotte, Kjeldsen, Tina E, Kjems, Jørgen, Lamy, Philippe, Venø, Morten T, Yan, Yan   +7 more
core   +2 more sources

Radiogenomics in clear cell renal cell carcinoma: correlations between advanced CT imaging (texture analysis) and microRNAs expression [PDF]

, 2019
Purpose: A relevant challenge for the improvement of clear cell renal cell carcinoma management could derive from the identification of novel molecular biomarkers that could greatly improve the diagnosis, prognosis, and treatment choice of these ...
Badia, S., Bellini, D., Carbone, A., Caruso, D., Fazi, F., Laghi, A., Marigliano, C., Miglietta, S., Palleschi, G., Pastore, A. L., Petrozza, V., Rengo, M., Tito, C.   +12 more
core   +1 more source

miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]

, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria, Laface, Ilaria, Milani, Daniela, Neri, Luca M, Rimondi, Erika, Simioni, Carolina, Varano, Gabriele   +6 more
core   +1 more source

Liquid biopsy in clear cell renal cell carcinoma: Urinary miR-210-3p as emerging specific biomarker

European Urology Open Science, 2020
Themost common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC) that accounts for 70–80% of all renal malignancies. To date, no useful markers are available in clinical practice for early diagnosis and for optimal patient stratification. MicroRNAs, a class of small non-coding RNA, are emerging as promising molecules in the management of ...
M. Costantini, V. Petrozza, C. Tito, L. M. Giammusso, V. Sorrentino, J. Cacciotti, N. Porta, A. Iaiza, A. L. Pastore, A. Di Carlo, G. Simone, M. Gallucci, A. Carbone, F. Fazi   +13 more
openaire   +5 more sources

miR-210-3p regulates the proliferation and apoptosis of non-small cell lung cancer cells by targeting SIN3A. [PDF]

Exp Ther Med, 2019
Previous studies have indicated that microRNA (miR)-210-3p is upregulated in NSCLC, however, the specific mechanism underlying the role of miR-210-3p in NSCLC pathogenesis requires further investigation. The aim of the present study was to explore the roles of miR-210-3p in NSCLC and the associated mechanisms.
Ren J, Li X, Dong H, Suo L, Zhang J, Zhang L, Zhang J.   +6 more
europepmc   +4 more sources

Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation

Journal of Translational Medicine, 2022
Background Atrial fibrosis plays a critical role in the development of atrial fibrillation (AF). Exosomes are a promising cell-free therapeutic approach for the treatment of AF.
Hongting Hao, Sen Yan, Xinbo Zhao, Xuejie Han, Ning Fang, Yun Zhang, Chenguang Dai, Wenpeng Li, Hui Yu, Yunlong Gao, Dingyu Wang, Qiang Gao, Yu Duan, Yue Yuan, Yue Li   +14 more
doaj   +1 more source

Downregulation of miR-210-3p Attenuates High Glucose-Induced Angiogenesis of Vascular Endothelial Cells via Targeting FGFRL1

Ophthalmic Research, 2023
Introduction: Vascular endothelial cell injury and angiogenesis induced by hyperglycemia are the main pathological basis of vascular complications in diabetes mellitus. Our study aimed to investigate the role and mechanism of miR-210-3p in high glucose (HG)-induced angiogenesis. Methods: Human umbilical vein endothelial cells (HUVECs) were treated with
Tao, Wen, Yiwen, Hong, Yamei, Cui, Jianying, Pan, Yishen, Wang, Yan, Luo   +5 more
openaire   +2 more sources