miR-370-3p Regulates Adipogenesis through Targeting Mknk1 [PDF]
Molecules, 2021 Excessive fat accumulation can lead to obesity, diabetes, hyperlipidemia, atherosclerosis, and other diseases. MicroRNAs are a class of microRNAs that regulate gene expression and are highly conserved in function among species.
Peiwen Zhang +14 more
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miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5 [PDF]
Stem Cells International, 2021 miRNAs play a crucial part in multiple biological processes of cell proliferation, migration, apoptosis, and chemoresistance. In cancer, miRNAs can be divided into oncogenes or tumor suppressors on the basis of their functions in the carcinogenic process.
Jiahui Mao +7 more
doaj +5 more sources
miR-370-3p affects the progression of postmenopausal osteoporosis through targeting INO80 [PDF]
HereditasBackground Postmenopausal osteoporosis (PMO) is acknowledged as a principal category of osteoporosis (OP). The aim of this study was to investigate the level of miR-370-3p in PMO patients and its predictive effect on osteoporosis in postmenopausal women,
Zhen Yang +4 more
doaj +3 more sources
circFNDC3B promotes esophageal squamous cell carcinoma progression by targeting MYO5A via miR-370-3p/miR-136-5p [PDF]
BMC Cancer, 2023 Background Esophageal squamous cell carcinoma (ESCC) is a prevalent malignant tumor worldwide. Circular RNA (circRNA) is of great value in tumorigenesis progression. However, the mechanism of circFNDC3B in ESCC remains to be clarified.
Dan Song +4 more
doaj +4 more sources
Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells [PDF]
Scientific Reports, 2023 Endothelial dysfunction and inflammatory immune response trigger dedifferentiation of vascular smooth muscle cells (SMCs) from contractile to synthetic phenotype and initiate arterial occlusion.
Yerin Kim +10 more
doaj +4 more sources
CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis [PDF]
Cardiovascular Therapeutics, 2022 Background. Circular RNA Transformation/Transcription Domain Associated Protein (circTRRAP, hsa_circ_0081241) was abnormally upregulated in acute myocardial infarction (AMI) patients. However, its biological role and functional mechanism in AMI remain to
Yuan Zhang +5 more
doaj +4 more sources
MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis [PDF]
Journal of Orthopaedic TranslationObjectives: Osteonecrosis of the femoral head (ONFH) represents a severe complication of glucocorticoids (GCs) therapy in clinical settings. MicroRNAs (miRNAs) are critically involved in the progression of GCs-induced ONFH, with ferroptosis playing a ...
Rongtai Zuo +7 more
doaj +2 more sources
miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4 [PDF]
CellsThe proliferation and maturation of hair follicles in follicular papilla cells are predominantly governed by miRNAs, which significantly influence the cell cycle, apoptosis, and proliferation.
Jiaqi Fu +9 more
doaj +2 more sources
Circular RNA hsa-circ-0005238 enhances trophoblast migration, invasion and suppresses apoptosis via the miR-370-3p/CDC25B axis [PDF]
Frontiers in Medicine, 2022 BackgroundFetal growth restriction (FGR) is attributed to various maternal, fetal, and placental factors. Trophoblasts participate in the establishment and maintenance of pregnancy from implantation and placentation to providing nutrition to fetus ...
Zhuomin Huang +4 more
doaj +2 more sources
Silencing of long non-coding RNA KCNQ1OT1 alleviates LPS-induced lung injury by regulating the miR-370-3p/FOXM1 axis in childhood pneumonia [PDF]
BMC Pulmonary Medicine, 2021 Purpose Long non-coding RNAs (lncRNAs) play important roles in the development of pneumonia. We aimed to explore the role of the lncRNA KCNQ1OT1 in pneumonia and its underlying mechanisms.
Ping Wang +3 more
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