Results 31 to 40 of about 4,858 (119)

Serum exosomal microRNA-370-3p and microRNA-196a-5p are potential biomarkers for the diagnosis and prognosis of hepatocellular carcinoma

Folia Histochemica et Cytobiologica, 2022
INTRODUCTION: Evidence has shown that some microRNAs (miRNAs) play a role in tumorigenesis of hepatocellular carcinoma (HCC). Herein, we aimed to evaluate the diagnostic and prognostic values of serum exosomal miR-370-3p and miR-196a-5p in patients with ...
Yaning Wei, Qian Zhang, Lin An, Guotao Fang, Dan Hong, Ting Jiao, Hua Yang, Zhiyu Wang   +7 more
doaj   +1 more source

LncMyoD Promotes Skeletal Myogenesis and Regulates Skeletal Muscle Fiber-Type Composition by Sponging miR-370-3p. [PDF]

Genes (Basel), 2021
The development of skeletal muscle is a highly ordered and complex biological process. Increasing evidence has shown that noncoding RNAs, especially long-noncoding RNAs (lncRNAs) and microRNAs, play a vital role in the development of myogenic processes.
Zhang P, Du J, Guo X, Wu S, He J, Li X, Shen L, Chen L, Li B, Zhang J, Xie Y, Niu L, Jiang D, Li X, Zhang S, Zhu L.   +15 more
europepmc   +4 more sources

lncRNA BCAR4 sponges miR‑370‑3p to promote bladder cancer progression via Wnt signaling. [PDF]

Int J Mol Med, 2020
Accumulating evidence suggests that the aberrant expression of long non‑coding RNAs (lncRNAs) is involved in the initiation, development and metastasis of bladder cancer (BC). Although several differentially expressed lncRNAs have been identified via lncRNA expression profiling of BC tissues, their functions and the molecular mechanisms underlying ...
Zhang R, Wang J, Jia E, Zhang J, Liu N, Chi C.   +5 more
europepmc   +4 more sources

Yinchenhao Decoction Protects Against Intrahepatic Cholestasis During Pregnancy Through the miR-370-3p/TM9SF4/KIT Axis. [PDF]

Biomed Res Int
Objective: The objective is to explore the potential pathogenesis and therapeutic mechanism of Yinchenhao decoction (YCHD) in intrahepatic cholestasis of pregnancy (ICP) by focusing on the regulatory role of exosomal miR‐370‐3p on target genes TM9SF4 and KIT.Methods: Exosomes were isolated from the serum samples of normal pregnant women (control ...
Jiang H, Yu W, Tao X, Yan Q, Zhou G, Chen C, Han G.   +6 more
europepmc   +3 more sources

Circ_UBE2D2 Attenuates the Progression of Septic Acute Kidney Injury in Rats by Targeting miR-370-3p/NR4A3 Axis. [PDF]

J Microbiol Biotechnol, 2022
As circ_UBE2D2 has been confirmed to have targeted binding sites with multiple miRNAs involved in septic acute kidney injury (SAKI), efforts in this study are directed to unveiling the specific role and relevant mechanism of circ_UBE2D2 in SAKI. HK-2 cells were treated with lipopolysaccharide (LPS) to construct SAKI model in vitro. After sh-circ_UBE2D2
Huang Y, Zheng G.
europepmc   +3 more sources

[Erratum] circRNA_001275 upregulates Wnt7a expression by competitively sponging miR‑370‑3p to promote cisplatin resistance in esophageal cancer. [PDF]

Int J Oncol, 2020
Circular RNAs (circRNAs) are aberrantly expressed in various tumors and are associated with tumorigenesis. The present study aimed to determine the role of circRNA_001275 in cisplatin‑resistant esophageal cancer. Three pairs of cisplatin‑resistant tissues and corresponding adjacent tissues were collected and subjected to circRNA chip analysis ...
Zou FW, Yang SZ, Li WY, Liu CY, Liu XH, Hu CH, Liu ZH, Xu S.   +7 more
europepmc   +6 more sources

Silencing circ_0006104 inhibits the proliferation, activation and collagen synthesis by mouse cardiac fibroblasts through up-regulation of miR-370-3p [PDF]

Jichu yixue yu linchuang, 2022
Objective To explore the function and mechanism of circular RNA 0006104 (circ_0006104) in regulating proliferation, activation and extracellular matrix (ECM) synthesis of cardiac fibroblasts (CFs) induced by angiotensin Ⅱ (Ang Ⅱ).
LI Ya-fei, DU Ying-qiang, WANG Ze-mu, ZHANG Jun
doaj   +1 more source

Circ_0035292 knockdown alleviates lipopolysaccharide (LPS)‐induced WI‐38 cell apoptosis and inflammatory injury

Immunity, Inflammation and Disease, 2023
Background Circular RNAs have emerged as important regulators in the pathogenesis of human diseases, including infantile pneumonia (IP). In this study, we aimed to explore the effects of circ_0035292 on lipopolysaccharide (LPS)‐treated Wistsar Institute (
Ying Guo, Zhouzhen Li, Chen Cheng
doaj   +1 more source

miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker

Molecular Therapy: Nucleic Acids, 2018
In the last decade, microRNAs (miRs) have been described as biomarkers and therapeutic agents. Based on this finding, our aim here is to know if (1) miRNA-370-3p can be used as a biomarker associated with a favorable survival and if (2) miRNA-370-3p can ...
Arulraj Nadaradjane, Joséphine Briand, Gwenola Bougras-Cartron, Valentine Disdero, François M. Vallette, Jean-Sébastien Frenel, Pierre-François Cartron   +6 more
doaj   +1 more source

Wnt7a and miR-370-3p: new contributors to bladder cancer invasion

Biotarget, 2018
In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.
Danielle, Scheunemann, Anjan K, Pradhan, Swadesh K, Das, Devanand, Sarkar, Luni, Emdad, Paul B, Fisher   +5 more
openaire   +2 more sources