Results 81 to 90 of about 264,171 (312)
Advanced Functional Materials, EarlyView.Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk +3 more
wiley +1 more source
Acetylcarnitine metabolism in blowfly flight muscle mitochondria [PDF]
FEBS Letters, 1975 Carnitine is involved in the movement of acetylCOA and fatty acyl-CoA into the matrices of mammalian mitochondria, where they are oxidized [ 1 ] . In some insects, carnitine may have a different role. Blowfly flight muscle mitochondria will not oxidize palmitoylcarnitine as they do not contain the enzymes for fatty acid oxidation [2,3], and they cannot
Danks, Susan M., Chappell, J.B.
openaire +2 more sources
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Redox Biology, 2019 Previous studies indicate that mitochondria-localized lactate dehydrogenase (mLDH) might be a significant contributor to metabolism. In the heart, the presence of mLDH could provide cardiac mitochondria with a higher capacity to generate reducing ...
Kyle L. Fulghum +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang +13 more
wiley +1 more source
Frontiers in Bioscience-LandmarkBackground: Mitochondria are essential for cellular energy production and cell survival. Mitochondrial dysfunction has been implicated in various neurological disorders, prompting the development of novel therapeutic approaches ...
Da-Wei Huang +8 more
doaj +1 more source
Nature Communications, 2022 How different physical configurations between sarcomeres and mitochondria alter energetic support for contractile function of skeletal muscle is not clear.
Prasanna Katti +8 more
doaj +1 more source
Osmotic Effects on Mitochondria from Two Species of Amphibian, Bufo marinus and Rana catesbeiana
, 1991 The effects ql ionic and/or osmotic change on skeletal muscle mitochondrial performance were investigated. Two substrates, pyruvate and glutamate, and variation in osmotic pressure from 205 to 360 mosm in KCl or mannitol/sucrose media had no effect on ...
Duerr, Jeff
core +1 more source
Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. [PDF]
, 2017 Transverse (T)-tubules make-up a specialized network of tubulated muscle cell membranes involved in excitation-contraction coupling for power of contraction. Little is known about how T-tubules maintain highly organized structures and contacts throughout
Fujita, Naonobu +10 more
core +2 more sources
Advanced Materials Technologies, EarlyView.This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li +7 more
wiley +1 more source