Results 241 to 250 of about 123,664 (300)

Transcriptomic stress responses in Vaccinium spp. F1 hybrids: Implications for temperature‐resilient cranberry breeding using a crop wild relative

PLANTS, PEOPLE, PLANET, EarlyView.
Climate extremes threaten the sustainability of cranberry production, a culturally and economically important North American crop. This study demonstrates that wild cranberries (Vaccinium oxycoccos) harbor genetic variation that may enhance cold stress resilience when introduced into cultivated cranberry through hybridization.
Audrey Dickinson, Jackson Kubal, Nicholas Allsing, Emily Murray, Todd P. Michael, James J. Polashock   +5 more
wiley   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Chinese leek-derived extracellular vesicles ameliorate sarcopenia by regulating mitochondrial biogenesis and autophagy via AMPK and maintaining myosin homeostasis. [PDF]

J Nanobiotechnology
Qi W, Yang L, Pan Y, Lv K, Zhao L, Zhang Y, Kai G, Sun Y, Pan H, Wang D.   +9 more
europepmc   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

The role of mitochondrial biogenesis, mitochondrial dynamics and mitophagy in gastrointestinal tumors. [PDF]

Cancer Cell Int
Liu Y, Wang H, Zhang S, Peng N, Hai S, Zhao H, Liu J, Liu W.   +7 more
europepmc   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

PGC-1 alpha regulates mitochondrial biogenesis to promote silica-induced pulmonary fibrosis. [PDF]

Toxicol Res (Camb)
Han X, Zhang M, Daowei L, Liu L, Ma X, Xiong Y, Yang H, Liu Z, Zhang N.   +8 more
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Rutin Suppresses EMT and Induces Mitochondrial Biogenesis <i>via</i> ER Stress-linked AMPK/SIRT1 Signaling in Prostate Cancer Cells. [PDF]

Cancer Genomics Proteomics
Chen SH, Wu RC, Huang WL, Wu CH, Mai HC, Yang YL, Hsieh PF, Lin VC, Ou CH.   +8 more
europepmc   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source