Investigating the Antidepressant Mechanism of Acupuncture with a Focus on Mitochondrial Homeostasis. [PDF]
Wei Y, Ma Z, Xu N, He Y, Cao M, Wang L.
europepmc +1 more source
HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma
What's new? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang +15 more
wiley +1 more source
Bridging tradition and modernity: mitochondrial dynamics as a Traditional Chinese Medicine therapeutic target in cardiovascular disease. [PDF]
Du C +10 more
europepmc +1 more source
Metabolism Controls the Timing of Human Brain Development and Maturation
ABSTRACT Among primates the human brain is the largest in size, exhibiting a higher neuronal density and connectivity. The prolonged expansion and subsequent connectome reorganization of the human brain have been suggested to promote higher cognitive and behavioral abilities.
Valentina Rava +3 more
wiley +1 more source
ABSTRACT Aim The liver exhibits a remarkable regenerative capacity, enabling this organ to maintain homeostasis even after significant injury. However, hepatic regeneration requires sufficient energy to sustain cellular hypertrophy and proliferation, thus ensuring efficient tissue repair.
A. L. Vieira‐da‐Silva +7 more
wiley +1 more source
Targeting mitochondrial quality control in diabetic kidney disease: emerging therapeutic opportunities. [PDF]
Luo J +5 more
europepmc +1 more source
Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons [PDF]
Drerup, Catherine M +3 more
core +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Mechanisms and therapeutic potential of mitochondrial-targeted therapies in bone repair. [PDF]
Xu N, Ma W, Liu G, Yang F.
europepmc +1 more source
Regulation of Mitochondrial Fission Factor (MFF) in metabolic homeostasis
openaire +1 more source

