Results 51 to 60 of about 1,253,804 (210)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Fish oil and omega3 in the prevention of metabolic disorders linked to obesity: role of mitochondrial function [PDF]
, 2011 Obesity is one of the most serious public health problems of the 21st century. Along with the increase in obesity, there is a parallel increase in the prevalence of type 2 diabetes, impaired glucose tolerance, atherogenic dyslipidemia (high plasma ...
Pignalosa, Angelica
core +1 more source
Ecotoxicology and Environmental Safety, 2023 Triphenyl phosphate (TPHP) is a widely used organophosphate flame retardant and has biological toxicity. Previous studies showed TPHP can restrain testosterone biosynthesis in Leydig cells, while the underlying mechanisms remain unclear.
Minxin Wang +9 more
doaj +1 more source
The Mitochondrial Chaperone Protein TRAP1 Mitigates α-Synuclein Toxicity [PDF]
, 2012 Overexpression or mutation of alpha-Synuclein is associated with protein aggregation and interferes with a number of cellular processes, including mitochondrial integrity and function.
Butler, Erin K. +41 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Mitochondria- and ER-associated actin are required for mitochondrial fusion
Nature CommunicationsMitochondria are crucial for cellular metabolism and signalling. Mitochondrial activity is modulated by mitochondrial fission and fusion, which are required to properly balance metabolic functions, transfer material between mitochondria, and remove ...
Priya Gatti +4 more
doaj +1 more source
Drp1 ablation in the adult mouse forebrain [PDF]
, 2014 Due to their high energy demand, their highly polarized nature and the sheer length of their processes, neurons - more than any other cell type - depend on a well-balanced dynamic mitochondrial network.
Oettinghaus, Bjorn
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Colorimetry in Nuclear Fusion Research
, 2022 0000-0001-5522-3082Colorimetry is a unique technique among research fields. The technique is also utilized in nuclear fusion research. The motivation is to evaluate the wide range of distribution of the deposition layer on the surface of the vacuum ...
MOTOJIMA, Gen, 66700
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2016 Mitochondrial function is dependent upon mitochondrial structure which is in turn dependent upon mitochondrial dynamics, including fission, fusion, and motility.
Laken C. Woods +2 more
doaj +1 more source