Results 221 to 230 of about 53,504 (295)

Reduced Oligodendrocyte Density and Axonal Caliber Associated With Mitochondrial Alterations in the White Matter of Chronically‐Starved Mice

International Journal of Eating Disorders, Volume 59, Issue 5, Page 869-884, May 2026.
ABSTRACT Objective Anorexia nervosa (AN) is a severe eating disorder associated with extreme weight loss, hyperactivity, and amenorrhea. Neuroimaging studies revealed brain atrophy and disruption of white matter integrity in the corpus callosum (CC) of patients with AN. However, the underlying pathophysiological mechanisms remain unclear.
Stephan Lang, Annelie Zimmermann, Kaja Dickert, Hanna Rupprecht, Julia Priebe, Fabienne Haberland, Hanna‐Sophia Henschke, Katharina Schuster, Marcus Frank, Linda Frintrop   +9 more
wiley   +1 more source

Deciphering Bax Dynamics: Regulation, Retrotranslocation, and Mitochondrial Interplay in the Commitment to Apoptosis: A Narrative Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background The apoptotic pathway mediated by mitochondria depends on the activation of pro‐apoptotic Bcl‐2 proteins Bax and Bak. When they permeabilize the outer mitochondrial membrane (OMM), mitochondrial dysfunction occurs, leading to caspase activation.
Mehrin Haque Tanisha, Md. Ayman Siddique, Zubaier Ahmed, Nashrah Mustafa, Fariha Tasneem   +4 more
wiley   +1 more source

Cyclic tensile loading regulates nucleus pulposus cell autophagy through mitochondrial dynamics: molecular mechanisms and implications. [PDF]

J Transl Med
Xue S, Soleimani Samarkhazan H.
europepmc   +1 more source

Metabolism Controls the Timing of Human Brain Development and Maturation

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Among primates the human brain is the largest in size, exhibiting a higher neuronal density and connectivity. The prolonged expansion and subsequent connectome reorganization of the human brain have been suggested to promote higher cognitive and behavioral abilities.
Valentina Rava, Erica Cannone, Maura Francolini, Elena Taverna   +3 more
wiley   +1 more source

Investigating the Antidepressant Mechanism of Acupuncture with a Focus on Mitochondrial Homeostasis. [PDF]

Int J Gen Med
Wei Y, Ma Z, Xu N, He Y, Cao M, Wang L.
europepmc   +1 more source

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

Targeting NME3 to Restore Mitochondrial Fission-Fusion Balance Defines a Novel Disease-Modifying Strategy for Parkinson's Disease. [PDF]

CNS Neurosci Ther
Qiao C, Hu XQ, Xu SH, Yao MF, Liu JP, Cao L.   +5 more
europepmc   +1 more source

Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons [PDF]

, 2017
Drerup, Catherine M, Herbert, Amy L, Monk, Kelly R, Nechiporuk, Alex V   +3 more
core   +1 more source

Proteolytic control of mitochondrial protein translocases

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondria are essential organelles that drive numerous cellular processes, including energy metabolism, ion homeostasis, and programmed cell death. This functional versatility relies on a highly dynamic proteome whose composition is continuously remodeled to meet changing cellular and environmental demands.
Lara Kroczek, Thomas Langer
wiley   +1 more source

Mitochondrial Calcium Signaling in Hepatocyte Health and Disease. [PDF]

Cold Spring Harb Perspect Biol
Eberhardt DR, Chaudhuri D.
europepmc   +1 more source