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Mitochondrial Fusion and Fission in Mammals [PDF]

open access: yesAnnual Review of Cell and Developmental Biology, 2006
Eukaryotic cells maintain the overall shape of their mitochondria by balancing the opposing processes of mitochondrial fusion and fission. Unbalanced fission leads to mitochondrial fragmentation, and unbalanced fusion leads to mitochondrial elongation ...
David C Chan
exaly   +6 more sources

Mitochondrial fusion, fission, and mitochondrial toxicity [PDF]

open access: yesToxicology, 2017
Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as well as processes such as intracellular transport. These processes maintain mitochondrial homeostasis, regulate mitochondrial form, volume and function, and are increasingly ...
Joel N. Meyer, Anthony L Luz
exaly   +3 more sources

Mitochondrial Fission and Fusion in Tumor Progression to Metastasis

open access: yesFrontiers in Cell and Developmental Biology, 2022
Mitochondria are highly dynamic organelles which can change their shape, via processes termed fission and fusion, in order to adapt to different environmental and developmental contexts. Due to the importance of these processes in maintaining a physiologically healthy pool of mitochondria, aberrant cycles of fission/fusion are often seen in ...
M Cecilia CaĆ­no, Dillon Boulton
exaly   +4 more sources

Mitochondrial fission/fusion dynamics and apoptosis [PDF]

open access: yesMitochondrion, 2010
Mitochondria play an important role in the progression of apoptosis through the release of pro-apoptotic factors, such as cytochrome c, from the mitochondrial intermembrane space. During this process, mitochondrial networks are dramatically reorganised from long filamentous interconnected tubules into small punctate spheres.
Seamus Martin, Clare Sheridan
exaly   +4 more sources

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