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The Genetics of Mitochondrial Fusion and Fission
2011Mitochondrial research has undergone a true renaissance in the last few years. One can hardly pick up one of the top basic research or clinical research journals without seeing a new discovery about mitochondrial function in cellular/human health and disease. This book describes the most important aspects of mitochondrial function in neurodegeneration.
Eliana Y. L. Chan +2 more
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Mitochondrial fission and fusion machineries
2004Mitochondria are dynamic organelles, often fusing and dividing in response to changes in the cellular environment, during cell division and differentiation and under many other circumstances that affect mitochondrial function. Mitochondrial division is also an integral part of the apoptotic pathway in mammalian cells.
Lorena Griparic +2 more
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Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration
Acta Neuropathologica, 2006Mitochondrial dysfunction is increasingly being recognized as an important factor contributing to the pathogenesis of neurodegenerative disorders. However, at present, the molecular basis underlying the decline in mitochondrial function is not really understood, but recent experimental evidence has shed some light on the pivotal role of mitochondrial ...
Stephan Frank
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Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases
New England Journal of Medicine, 2013Mitochondria fuse and divide in response to cell demands and environment. Alterations in mitochondrial dynamics underlie various human diseases, including cancer and neurologic and cardiovascular diseases. Defining the alterations may identify potential therapeutic targets.
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Intersection between Mitochondrial Permeability Pores and Mitochondrial Fusion/Fission
Neurochemical Research, 2007The goal of this review is to highlight recent developments in the field of mitochondrial membrane processes, which provide new insights into the relation between mitochondrial fission/fusion events and the mitochondrial permeability transition (MPT).
Irina G, Gazaryan, Abraham M, Brown
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Mitochondrial fission and fusion in neurodegenerative diseases:Ca2+ signalling
Molecular and Cellular NeuroscienceNeurodegenerative diseases (NDs) are a group of disorders characterized by the progressive loss of neuronal structure and function. The pathogenesis is intricate and involves a network of interactions among multiple causes and systems. Mitochondria and Ca2+ signaling have long been considered to play important roles in the development of various NDs ...
Xuan, Liu +4 more
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Mitochondrial fusion and fission in health and disease
2018© 2017 Elsevier Inc. Available online 7 February 2018.
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