Results 111 to 120 of about 2,978 (195)

Control of mitochondrial dynamics by a fusogenic lipid. [PDF]

Trends Cell Biol, 2023
Yang Z, Chan DC.
europepmc   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

Cancer Science, Volume 117, Issue 6, Page 1554-1565, June 2026.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka, Shuhei Hirose, Yu Wang, Tomonori Yaguchi, Kenji Chamoto   +4 more
wiley   +1 more source

Short‐term high‐fat feeding induces muscle‐type–specific signaling adaptations in skeletal muscle of male rats

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Short‐term high‐fat diet (HFD) feeding is used to study metabolic dysregulation, yet many rodent models use extreme fat contents that may not reflect physiological conditions. Skeletal muscle responses to short‐term HFD also vary by muscle type.
Arata Tsutaki, Hidetaka Imagita, Asumi Yoshida   +2 more
wiley   +1 more source

Aortic Segments‐Depending Hypertensive Remodeling Is Driven by Mitochondrial Fusion Dysfunction

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
A region‐specific protective function of OPA1 within the aortic wall under severe hypertensive stress. ABSTRACT OPA1 haploinsufficiency exacerbates severe hypertension‐induced aortic remodeling in a segment‐specific manner, revealing differential vulnerability between the suprarenal abdominal aorta (SRAA) and the descending thoracic aorta (DTA). In the
Alexis Richard, Alicia Baptista Vicente, Clara Gourhand, Antoine Ducroix, Pauline Robert, Bertrand Toutain, Linda Grimaud, Emilie Vessières, Agnès Toutain‐Barbelivien, Guy Lenaers, Juan‐Manuel Chao de la Barca, Olivier Fouquet, Daniel Henrion, Céline Fassot, Laurent Loufrani   +14 more
wiley   +1 more source

Mitofusin 1 in mitochondrial quality control and anti-inflammatory responses in nucleus pulposus cells during disc degeneration

Scientific Reports
Mitochondrial dysfunction drives intervertebral disc degeneration, and mitochondrial dynamics are regulated by mitofusins (MFNs). In this study, we evaluated the roles of MFN1 and MFN2 in mitochondrial quality control and their responses to inflammation ...
Jae Won Shin, Young Mi Kang, Hak Sun Kim, Seong Hwan Moon, Kyung Soo Suk, Si Young Park, Byung Ho Lee, Ji Won Kwon   +7 more
doaj   +1 more source

OPA1 in MC4R Neurons Regulates Dietary Fat Intake and Body Weight in Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Soybean oil intake induces OPA1 expression in hypothalamic MC4R neurons, contributing to adaptive regulation of appetite. MC4R neuron‐specific OPA1 deficiency increases soybean oil consumption and leads to obesity, with a more pronounced effect in females.
Shigenobu Matsumura, Mizuki Fujiwara, Soyoka Horie, Miona Marutani, Eri Nousou, Nanase Iki, Yuka Yamato, Yui Otonashi, Tsutomu Sasaki, Mina Fujitani, Teppei Fujikawa   +10 more
wiley   +1 more source

Mitofusin-2 [PDF]

, 2020
openaire   +1 more source

The Acidic Conductor: How Tumor Acidosis Orchestrates Metabolic Adaptation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Chen Xu, Tao Yang, Xinghua Long
wiley   +1 more source

Genetic studies of normal tension glaucoma [PDF]

Клиническая офтальмология
D.Yu. Plotnikov, E.V. Valeeva Kazan State Medical University, Kazan, Russian Federation The paper presents a review of literature on genetic studies of normal tension glaucoma (NTG).
D.Yu. Plotnikov, E.V. Valeeva
doaj  

Mitofusin MFN2 acts as a molecular sensor preventing protein aggregation and mitophagy, with a protective effect against apoptosis in Charcot-Marie-Tooth type 2A disease. [PDF]

Autophagy Rep
Joaquim M, Dohrn MF, Chevrollier A, Escobar-Henriques M.   +3 more
europepmc   +1 more source