Results 221 to 230 of about 130,672 (286)

The mitotic spindle kinase MSK co-ordinates segregation of the nucleus and kinetoplast in Leishmania mexicana

Carnielli JBT, Geoghegan V, Brannigan JA, Saldivia M, Hughes C, Lima APCA, Motta MCM, Dowle A, Wilkinson AJ, Mottram JC.   +9 more
europepmc   +1 more source

Oridonin‐Loaded PDA@Gel@GO Nanocapsules Modulate NLRP3 and Epithelial Repair in Colitis

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Mechanism of galactosylated carboxymethyl chitosan nanomicelle oral microcapsules delivering oridonin in alleviating colitis via targeting the NLRP3 inflammasome. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory bowel disease marked by sustained mucosal inflammation and epithelial barrier dysfunction, closely associated with aberrant NOD‐like
Wenbo Yuan, Qirui Zhao, Jing Hua, Lingyao Xu, Yufan Wang, Tongtong Xu, Zuchao Du, Liping Wu, Daxiang Cui   +8 more
wiley   +1 more source

Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function. [PDF]

Adv Sci (Weinh)
Zhang Z, Chen J, Ma R, Xu C, Lu Y, Zhou J, Xia K, Lu P.   +7 more
europepmc   +1 more source

Kinesin-5/Cut7 C-terminal tail phosphorylation is essential for microtubule sliding force and bipolar mitotic spindle assembly. [PDF]

Curr Biol
Jones MH, Gergely ZR, Steckhahn D, Zhou B, Betterton MD.   +4 more
europepmc   +1 more source

Mechanisms underlying Myosin 10's contribution to the maintenance of mitotic spindle bipolarity. [PDF]

Mol Biol Cell
Yim YI, Pedrosa A, Wu X, Chinthalapudi K, Cheney RE, Hammer JA.   +5 more
europepmc   +1 more source

A missense SNP in the tumor suppressor SETD2 reduces H3K36me3 and mitotic spindle integrity in Drosophila. [PDF]

Genetics
Brockett JS, Manalo T, Zein-Sabatto H, Lee J, Fang J, Chu P, Feng H, Patil D, Davidson P, Ogan K, Master VA, Pattaras JG, Roberts DL, Bergquist SH, Reyna MA, Petros JA, Lerit DA, Arnold RS.   +17 more
europepmc   +1 more source

Development of Styryl‐Modified 3,4‐Dihydropyrimidin‐2(1H)‐ones as Potential Antitumor Agents

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Styryl‐modified 3,4‐dihydropyrimidin‐2(1H)‐ones (DHPMs), designed from the Eg5 inhibitor monastrol, show markedly enhanced antiproliferative activity in HeLa and MCF‐7 cancer cells. Lead compounds 16 and 17 trigger apoptosis through cell‐line‐specific pathways and downregulate c‐Myc, emerging as promising anticancer candidates.
Konstantinos Panagoulias, Woonghee Kim, Murat Ozdemir, Busra Turan, Adil Mardinoglu, Hasan Turkez, Daniela Trisciuzzi, Orazio Nicolotti, Antonio Di Stefano, Stamatia Vassiliou, Ivana Cacciatore   +10 more
wiley   +1 more source

CTCF is essential for proper mitotic spindle structure and anaphase segregation. [PDF]

Chromosoma
Chiu K, Berrada Y, Eskndir N, Song D, Fong C, Naughton S, Chen T, Moy S, Gyurmey S, James L, Ezeiruaku C, Capistran C, Lowey D, Diwanji V, Peterson S, Parakh H, Burgess AR, Probert C, Zhu A, Anderson B, Levi N, Gerlitz G, Packard MC, Dorfman KA, Bahiru MS, Stephens AD.   +25 more
europepmc   +1 more source

miR-31-mediated local translation at the mitotic spindle is important for early development.

Development
Remsburg CM, Konrad KD, Testa MD, Stepicheva N, Lee K, Choe LH, Polson S, Bhavsar J, Huang H, Song JL.   +9 more
europepmc   +1 more source

CFDP1 regulates the stability of pericentric heterochromatin thereby affecting RAN GTPase activity and mitotic spindle formation. [PDF]

PLoS Biol
Gopinathan G, Xu Q, Luan X, Diekwisch TGH.   +3 more
europepmc   +1 more source