Results 221 to 230 of about 205,638 (297)

Centrosome‑, mitotic spindle‑ and cytokinetic bridge‑specific compartmentalization of AGO2 protein in human liver cells undergoing mitosis: Non‑canonical, RNAi‑dependent, control of local homeostasis. [PDF]

Mol Med Rep
Theotoki EI, Kakoulidis P, Nikolakopoulos KS, Vlachou EN, Tsitsilonis OE, Voutsinas GE, Anastasiadou E, Stravopodis DJ.   +7 more
europepmc   +1 more source

Apparent Endoscopic Decrease in the Size of a Large Ulcerated Gastric Schwannoma After Helicobacter pylori Eradication Therapy: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Gastric subepithelial lesions (SELs) comprise a heterogeneous group of tumors, among which gastric schwannomas are rare and generally benign. We report a case of a large gastric schwannoma with ulceration and symptomatic anemia that showed an apparent endoscopic decrease in size following Helicobacter pylori eradication.
Takahito Awatsu, Daisuke Asaoka, Hirofumi Fukushima, Daishi Kabemura, Yusuke Nomoto, Osamu Nomura, Kazunori Kajino, Mariko Hojo, Akihito Nagahara   +8 more
wiley   +1 more source

Discovery of a First‐in‐Class Dual‐Function TLX Activator by Microscale Library Synthesis and Direct‐to‐Biology Screening

Angewandte Chemie Novit, Volume 2, Issue 4, December 2026.
The transcription factor tailless (TLX) is an orphan nuclear receptor thought to maintain neural and retinal stem cell populations in a proliferating state to enable regeneration. Ligands to study TLX modulation were lacking. We developed a potent TLX agonist capable of activating TLX's transcriptional repressor and activator properties in an evolution‐
Tanja Stiller, Romy Busch, Giuseppe Faudone, Felia C. Haffelder, Jan Vietor, Arthur Kardanov, Úrsula López‐García, Arne Hackspacher, Georg Höfner, Vasily Morozov, Susanne F. Koch, Julian A. Marschner, Daniel Merk   +12 more
wiley   +1 more source

Identification of a Circular RNA as a Potential Diagnostic and Prognostic Biomarker in Breast Cancer Through Integrated Bioinformatic and Experimental Analyses

Analytical Science Advances, Volume 7, Issue 2, December 2026.
Forty circular RNAs were found to be significantly dysregulated in microarray datasets. Expression levels of hsa_circ_0000231 were significantly upregulated in breast cancer (BC) tissues, while hsa_circ_0011385 exhibited no significant difference in expression levels. This study also revealed that hsa_circ_0000231/hsa‐miR‐5683/CCNB1 regulatory axis may
MohamadReza Hashemi, Pejman Morovat, Azin Khoshghiafeh, Novin Nikbakhsh, Mohamadreza Ahmadifard   +4 more
wiley   +1 more source

FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton. [PDF]

Proc Natl Acad Sci U S A
Aquino-Perez C, Safaralizade M, Podhajecky R, Wang H, Lansky Z, Grosse R, Macurek L.   +6 more
europepmc   +1 more source

What Is Your Diagnosis? Blood Smear From a Mixed‐Breed Dog

Veterinary Clinical Pathology, EarlyView.
Laura S. Peres, Lina C. Bilhalva, Camila B. E. Mello, Abílio G. Silva, Andrea P. Santos, Stella F. Valle   +5 more
wiley   +1 more source

Systems‐level phosphoproteomics reveals calcium/calmodulin‐dependent protein kinase kinase 2‐driven kinase signaling underlying malignant phenotypes in gastric cancer

Journal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.
CAMKK2 inhibition induces extensive phosphoproteomic remodeling associated with cell cycle regulation, RNA processing, and kinase signaling networks in gastric cancer. Integrated systems‐level analyses identified dysregulated CDK, SRPK, MAPK, and AKT signaling pathways underlying malignant phenotypes and highlighted CAMKK2 as a potential therapeutic ...
Mohd. Altaf Najar, T. S. Keshava Prasad, Prashant Kumar Modi   +2 more
wiley   +1 more source

Antiparallel microtubule bundling supports KIF15-driven mitotic spindle assembly. [PDF]

Mol Biol Cell
Salazar BM, Ohi R.
europepmc   +1 more source

Molecular Control of Neural Stem Cell Quiescence in the Adult Zebrafish Telencephalon: Established Mechanisms and an Integrative Hypothesis

Glia, Volume 74, Issue 12, December 2026.
Adult zebrafish radial glia quiescence is controlled by at least four mechanisms: Notch3, BMP‐Id1, Nr2f1b and Midkine‐a. We propose these act as partially redundant inputs, biased along the antero‐posterior axis that set quiescence depth. ABSTRACT The zebrafish telencephalon is an excellent model for adult neurogenesis under physiological and ...
Mathilde Hoareau, Nicolas Diotel, Sepand Rastegar   +2 more
wiley   +1 more source

The molecular landscape of nodular fasciitis: novel USP6 fusions, genomic stability, and an exploratory clinicopathological model – a 20‐year retrospective study

The Journal of Pathology: Clinical Research, Volume 12, Issue 6, November 2026.
Abstract Nodular fasciitis (NF) is a benign myofibroblastic neoplasm characterized by rapid growth and recurrent USP6 rearrangements. Despite its benign nature, NF may exhibit worrisome histologic or clinical features that mimic sarcoma, posing diagnostic challenges.
Kristijan Skok, Maximilian T Buchwald, Maria Anna Smolle, Theresa Godschachner, Andreas Leithner, Christian Viertler, Bernadette Liegl‐Atzwanger   +6 more
wiley   +1 more source